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of 9
pro vyhledávání: '"Rotimi Sheyi"'
Autor:
Rotimi Sheyi, Jessica T. Mhlongo, Marta Jorba, Ester Fusté, Anamika Sharma, Miguel Viñas, Fernando Albericio, Paula Espinal, Beatriz G. de la Torre
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5883 (2024)
Peptides displaying antimicrobial properties are being regarded as useful tools to evade and combat antimicrobial resistance, a major public health challenge. Here we have addressed dendrimers, attractive molecules in pharmaceutical innovation and de
Externí odkaz:
https://doaj.org/article/03233f01dea746bda4d70872499956c3
Publikováno v:
Pharmaceutics, Vol 14, Iss 2, p 396 (2022)
As one of the major therapeutic options for cancer treatment, chemotherapy has limited selectivity against cancer cells. Consequently, this therapeutic strategy offers a small therapeutic window with potentially high toxicity and thus limited efficac
Externí odkaz:
https://doaj.org/article/5d137b73f3414880b6506be91a3f9a9c
Publikováno v:
Molecules, Vol 26, Iss 4, p 864 (2021)
This review provides an overview of the broad applicability of s-triazine. Our many years working with this intriguing moiety allow us to discuss its wide activity spectrum (inhibition against MAO-A and -B, anticancer/antiproliferative and antimicrob
Externí odkaz:
https://doaj.org/article/926c90c60312421d9baac108592f8782
Autor:
Anamika Sharma, Fernando Albericio, Beatriz G. de la Torre, Rotimi Sheyi, Ayman El-Faham, Ashok Kumar
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
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A unique property of 2,4,6-trichloro-1,3,5-triazine (TCT) is its ability to undergoes a nucleophilic aromatic substitution reaction (SNAr) under temperature-controlled conditions. Using a convenient and biologically friendly protocol, mono-substitute
Autor:
Beatriz G. de la Torre, Anamika Sharma, Rotimi Sheyi, Fernando Albericio, Ashok Kumar, Ayman El-Faham
Publikováno v:
Organic Letters. 21:7888-7892
An example of triorthogonal chemoselectivity is reported here for the first time. In this regard, a series of 43 reactions were performed using tridentate s-triazine as a model. In all of the possible cases, the three substitutions were carried out u
Autor:
Anamika Sharma, Beatriz G. de la Torre, Rakia Abd Alhameed, Fernando Albericio, Rotimi Sheyi, Ayman Al-Faham, Zainab M. Almarhoon
Publikováno v:
The 24th International Electronic Conference on Synthetic Organic Chemistry.
2,4,6-Trichloro-1,3,5-triazine (TCT) offers the unique ability to undergo sequential nucleophilic substitution reactions using regular nucleophiles (first Cl replacement at 0 °C, second at RT, and third at >90 °C), making s-triazine a privileged sc
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Molecules
Molecules, Vol 26, Iss 864, p 864 (2021)
instname
Molecules
Molecules, Vol 26, Iss 864, p 864 (2021)
This review provides an overview of the broad applicability of s-triazine. Our many years working with this intriguing moiety allow us to discuss its wide activity spectrum (inhibition against MAO-A and -B, anticancer/antiproliferative and antimicrob
Publikováno v:
Australian Journal of Chemistry. 73:352
2,4,6-Trichloro-1,3,5-triazine (TCT) is a privileged core that has the capacity to undergo sequential nucleophilic substitution reactions. Three nucleophiles, namely phenol, thiol and amine, were studied and the preferential order of incorporation on
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