Microbial-host co-metabolites are prodromal markers predicting phenotypic heterogeneity in behavior, obesity, and impaired glucose tolerance

Autor: Dumas, M-E, Rothwell, AR, Hoyles, L, Aranias, T, Chilloux, J, Calderari, S, Noll, EM, Péan, N, Boulangé, CL, Blancher, C, Barton, RH, Gu, Q, Fearnside, JF, Deshayes, C, Hue, C, Scott, J, Nicholson, JK, Gauguier, D

Publikováno v: Cell Reports
Cell Reports, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Elsevier Inc, 2017, 20 (1), pp.136-148. ⟨10.1016/j.celrep.2017.06.039⟩
Cell Reports, Vol 20, Iss 1, Pp 136-148 (2017)

Summary The influence of the gut microbiome on metabolic and behavioral traits is widely accepted, though the microbiome-derived metabolites involved remain unclear. We carried out untargeted urine 1H-NMR spectroscopy-based metabolic phenotyping in a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8ade711b283e249f5aa41ce1fbcf5134
https://ora.ox.ac.uk/objects/uuid:bb30e12a-8ecc-4451-9fa6-5cfb552927b3

Microbial-Host Co-metabolites Are Prodromal Markers Predicting Phenotypic Heterogeneity in Behavior, Obesity, and Impaired Glucose Tolerance.

Autor: Dumas ME; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK. Electronic address: m.dumas@imperial.ac.uk., Rothwell AR; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Hoyles L; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Aranias T; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Chilloux J; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Calderari S; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Noll EM; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Péan N; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Boulangé CL; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Blancher C; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Barton RH; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Gu Q; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Fearnside JF; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK., Deshayes C; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Hue C; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France., Scott J; Department of Medicine, Imperial College London, Du Cane Road, London W12 0NN, UK., Nicholson JK; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK., Gauguier D; Division of Computational and Systems Medicine, Department of Surgery and Cancer, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, Exhibition Road, South Kensington, London SW7 2AZ, UK; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK; Cordeliers Research Centre, INSERM UMR_S 1138, University Pierre & Marie Curie and University Paris Descartes, Sorbonne Paris Cité, Sorbonne Universities, 15 Rue de l'École de Médecine, 75006 Paris, France. Electronic address: dominique.gauguier@crc.jussieu.fr.

Publikováno v: Cell reports [Cell Rep] 2017 Jul 05; Vol. 20 (1), pp. 136-148.

Phylometabonomic patterns of adaptation to high fat diet feeding in inbred mice.

Autor: Fearnside JF; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom., Dumas ME, Rothwell AR, Wilder SP, Cloarec O, Toye A, Blancher C, Holmes E, Tatoud R, Barton RH, Scott J, Nicholson JK, Gauguier D

Publikováno v: PloS one [PLoS One] 2008 Feb 27; Vol. 3 (2), pp. e1668. Date of Electronic Publication: 2008 Feb 27.