Process and scaling parameters for wet media milling in early phase drug development: A knowledge based approach

Autor: Siewert, Christian, Moog, Regina, Alex, Rainer, Kretzer, Philipp, Rothenhäusler, Benno

Publikováno v: In European Journal of Pharmaceutical Sciences 30 March 2018 115:126-131

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Cannabinoid CB receptor ligand profiling reveals biased signalling and off-target activity

Autor: Soethoudt, Marjolein, Grether, Uwe, Fingerle, Jürgen, Grim, Travis W, Fezza, Filomena, de Petrocellis, Luciano, Ullmer, Christoph, Rothenhäusler, Benno, Perret, Camille, van Gils, Noortje, Finlay, David, MacDonald, Christa, Chicca, Andrea, Gens, Marianela Dalghi, Stuart, Jordyn, de Vries, Henk, Mastrangelo, Nicolina, Xia, Lizi, Alachouzos, Georgios, Baggelaar, Marc P, Martella, Andrea, Mock, Elliot D, Deng, Hui, Heitman, Laura H, Connor, Mark, Di Marzo, Vincenzo, Gertsch, Jürg, Lichtman, Aron H, Maccarrone, Mauro, Pacher, Pal, Glass, Michelle, van der Stelt, Mario

Publikováno v: Soethoudt, M, Grether, U, Fingerle, J, Grim, T W, Fezza, F, de Petrocellis, L, Ullmer, C, Rothenhäusler, B, Perret, C, van Gils, N, Finlay, D, MacDonald, C, Chicca, A, Gens, M D, Stuart, J, de Vries, H, Mastrangelo, N, Xia, L, Alachouzos, G, Baggelaar, M P, Martella, A, Mock, E D, Deng, H, Heitman, L H, Connor, M, Di Marzo, V, Gertsch, J, Lichtman, A H, Maccarrone, M, Pacher, P, Glass, M & van der Stelt, M 2017, ' Cannabinoid CB receptor ligand profiling reveals biased signalling and off-target activity ', Nature Communications, vol. 8, pp. 13958 . https://doi.org/10.1038/ncomms13958
Nature Communications, 8. Nature Publishing Group

The cannabinoid CB2 receptor (CB2R) represents a promising therapeutic target for various forms of tissue injury and inflammatory diseases. Although numerous compounds have been developed and widely used to target CB2R, their selectivity, molecular m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::79cb2270d7ac6960e1ec0aad30621279
https://research.vumc.nl/en/publications/d134365a-4610-4c84-93dc-8bd097450214

Surface plasmon microscopic characterization of external surfaces.

Autor: Hickel, Werner, Rothenhäusler, Benno, Knoll, Wolfgang

Publikováno v: Journal of Applied Physics; 11/15/1989, Vol. 66 Issue 10, p4832, 5p

NF‐κB activation in astrocytes drives a stage‐specific beneficial neuroimmunological response in ALS.

Autor: Ouali Alami, Najwa, Schurr, Christine, Olde Heuvel, Florian, Tang, Linyun, Li, Qian, Tasdogan, Alpaslan, Kimbara, Atsushi, Nettekoven, Matthias, Ottaviani, Giorgio, Raposo, Catarina, Röver, Stephan, Rogers‐Evans, Mark, Rothenhäusler, Benno, Ullmer, Christoph, Fingerle, Jürgen, Grether, Uwe, Knuesel, Irene, Boeckers, Tobias M., Ludolph, Albert, Wirth, Thomas

Publikováno v: EMBO Journal; Aug2018, Vol. 37 Issue 16, p1-1, 23p, 12 Color Photographs, 1 Diagram, 2 Charts, 7 Graphs