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pro vyhledávání: '"Rotenberg KS"'
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Autor:
Rotenberg Ks, Graves Da
Publikováno v:
Biopharmaceutics & Drug Disposition. 10:127-136
Five methods of absorption rate (Ka) estimation were compared using data from a previously reported bioavailability study: Wagner-Nelson (WN), asymptotic WN (AWN), the Hendeles-Weinberger modification of the WN (HW), nonlinear regression performed on
Publikováno v:
The Journal of Clinical Pharmacology. 27:139-143
The ability of healthy male volunteers to metabolize a 30-mg oral dose of dextromethorphan (DM) was studied in 252 Americans. Two blood samples were collected at four and 24 hours after administration of the dose. The resulting plasma was analyzed fo
Autor:
Graves Da, Lewis P. Amsel, Meyer Mc, Bhargava Ak, Straughn Ab, Wecker Mt, Hinsvark On, Rotenberg Ks
Publikováno v:
Biopharmaceutics & Drug Disposition. 9:267-272
The influence of a standard meal on the extent and rate of absorption of pseudoephedrine from a liquid controlled release (CR) formulation (Pennkinetic System) was studied in 16 normal male volunteers. Equivalent single doses of an immediate release
Publikováno v:
Journal of Pharmaceutical Sciences. 76:29-31
The influence of a standard meal on the extent and rate of absorption of pseudoephedrine from a controlled-release (CR) capsule formulation (Pennkinetic System) was studied in 16 normal male volunteers. Equivalent single doses of an immediate-release
Publikováno v:
Journal of pharmaceutical sciences. 77(12)
The in vivo performance of hydralazine sustained-release dosage forms prepared using an ethylcellulose-coated drug:resin complex was studied in healthy males who were determined to be slow acetylators. Two studies were performed. The first study (I)
Publikováno v:
Polymeric Materials in Medication ISBN: 9781489922472
A controlled release system employing ion exchange technology is described and serves as the basis for developing a coated drug polymer complex system known as the Pennkinetic System. This chapter describes recently developed suspension and capsule d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2f352b9924b49d0592bb7ef1e56459f
https://doi.org/10.1007/978-1-4899-2245-8_6
https://doi.org/10.1007/978-1-4899-2245-8_6
Publikováno v:
Journal of clinical pharmacology. 27(2)
A randomized, two-way, steady-state crossover study was performed in 24 healthy male volunteers to evaluate the bioavailability of a controlled-release (CR) dextromethorphan (DM) suspension. Only slow and intermediate DM metabolizers were allowed to
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Akademický článek
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