Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rotem Lange"'
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006860 (2017)
Dorsal closure (DC) is a developmental process in which two contralateral epithelial sheets migrate to seal a large hole in the dorsal ectoderm of the Drosophila embryo. Two signaling pathways act sequentially to orchestrate this dynamic morphogeneti
Externí odkaz:
https://doaj.org/article/58bfa569dbe849a38746c0ee4c2246e3
Autor:
Rotem Lange, Allan Bar-Sinai, Adi Salzberg, Ze'ev Paroush, Shaked Bar-Cohen, Tatyana Kushnir, David Engelberg, Navit Mooshayef, Helit Rozen
Publikováno v:
Genetics. 214:109-120
Excessive RTK signaling, often caused by activating mutations in Ras, Raf and/or MEK, occurs in most human tumors. Intriguingly, confirmed cancer-driver mutations in the downstream effector kinase, ERK, have not been reported. To test if... Receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1c16c338521ea040fb0d3440080c2f9
https://doi.org/10.1534/genetics.119.302794
https://doi.org/10.1534/genetics.119.302794
Autor:
Tatyana, Kushnir, Shaked, Bar-Cohen, Navit, Mooshayef, Rotem, Lange, Allan, Bar-Sinai, Helit, Rozen, Adi, Salzberg, David, Engelberg, Ze'ev, Paroush
Publikováno v:
Genetics
Receptor tyrosine kinase signaling plays prominent roles in tumorigenesis, and activating oncogenic point mutations in the core pathway components Ras, Raf, or MEK are prevalent in many types of cancer. Intriguingly, however, analogous oncogenic muta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::49a3db117bfe42666f0959e67cc26f7a
https://pubmed.ncbi.nlm.nih.gov/31740452
https://pubmed.ncbi.nlm.nih.gov/31740452
Publikováno v:
PLoS Genetics, Vol 13, Iss 6, p e1006860 (2017)
PLoS Genetics
PLoS Genetics
Dorsal closure (DC) is a developmental process in which two contralateral epithelial sheets migrate to seal a large hole in the dorsal ectoderm of the Drosophila embryo. Two signaling pathways act sequentially to orchestrate this dynamic morphogeneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac0efb428deba2c75246d4cf87837e8e
http://europepmc.org/articles/PMC5495517?pdf=render
http://europepmc.org/articles/PMC5495517?pdf=render
Autor:
Shira Anzi, Ze'ev Paroush, Tatyana Kushnir, Rotem Karni, Rotem Lange, Rona Grossman, T Zahavi, D Kornspan, Eitan Shaulian, Hovav Nechushtan, A Maimon, E Berger
Publikováno v:
Oncogene. 36(26)
Signaling mediated by the Ras-extracellular signal-regulated kinase (Erk) pathway often leads to the phosphorylation of transcriptional regulators, thereby modulating their activity and causing concerted changes in gene expression. In Drosophila, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9033b628ed1921d7e4155a4518e94fc1
https://pubmed.ncbi.nlm.nih.gov/28192406
https://pubmed.ncbi.nlm.nih.gov/28192406