Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Roswitha Beck"'
Autor:
Nadine Holzleitner, Sebastian Fischer, Isabel Maniyankerikalam, Roswitha Beck, Constantin Lapa, Hans-Jürgen Wester, Thomas Günther
Publikováno v:
EJNMMI Research, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Background We recently introduced radiohybrid (rh)-based minigastrin analogs e.g., DOTA-rhCCK-18 (DOTA-D-Dap(p-SiFA)-(D-γ-Glu)8-Ala-Tyr-Gly-Trp-Nle-Asp-Phe-NH2), that revealed substantially increased activity retention in the tumor. However
Externí odkaz:
https://doaj.org/article/793c094f567543f6a4050d4c4b105f85
Autor:
Jan-Philip Kunert, Max Müller, Thomas Günther, León Stopper, Nicole Urtz-Urban, Roswitha Beck, Hans-Jürgen Wester
Publikováno v:
EJNMMI Research, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Background Radioguided surgery (RGS) has recently emerged as a valuable new tool in the management of recurrent prostate cancer (PCa). After preoperative injection of a 99mTc-labeled prostate-specific membrane antigen (PSMA) inhibitor, radio
Externí odkaz:
https://doaj.org/article/302af4dc09574fd3a056938f28fa729c
Autor:
Melissa Antons, Magdalena Lindner, Eva Eilles, Lisa Günther, Astrid Delker, Christina Branner, Anja Krämer, Roswitha Beck, Rosel Oos, Max Wuehr, Sibylle Ziegler, Michael Strupp, Andreas Zwergal
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionBetahistine is widely used for the treatment of various vestibular disorders. However, the approved oral administration route and maximum daily dose are evidently not effective in clinical trials, possibly due to a major first-pass metabo
Externí odkaz:
https://doaj.org/article/e3c08a6f394144e983a815b193937226
Autor:
Max Wuehr, Eva Eilles, Magdalena Lindner, Maximilian Grosch, Roswitha Beck, Sibylle Ziegler, Andreas Zwergal
Publikováno v:
Biomolecules, Vol 13, Iss 11, p 1580 (2023)
Low-intensity noisy galvanic vestibular stimulation (nGVS) can improve static and dynamic postural deficits in patients with bilateral vestibular loss (BVL). In this study, we aimed to explore the neurophysiological and neuroanatomical substrates und
Externí odkaz:
https://doaj.org/article/eded45dc835f4ccc948448666bd5357e
Autor:
Alexander Wurzer, Mara Parzinger, Matthias Konrad, Roswitha Beck, Thomas Günther, Veronika Felber, Stefanie Färber, Daniel Di Carlo, Hans-Jürgen Wester
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Introduction Radiohybrid (rh) ligands, a novel class of prostate-specific membrane antigen (PSMA)-targeted radiopharmaceuticals, can be labeled either with [18F]fluorine via isotopic exchange or with radiometals (such as [68Ga]Gallium, [177L
Externí odkaz:
https://doaj.org/article/7ac00bd0ff594505bde0da78cf92916d
Publikováno v:
Pharmaceuticals, Vol 15, Iss 12, p 1467 (2022)
In order to enable 18F- and 177Lu-labelling within the same molecule, we introduced a silicon-based fluoride acceptor (SiFA) into the hexa-D-glutamate chain of DOTA-PP-F11N. In addition, minigastrin analogues with a prolonged as well as γ-linked D-g
Externí odkaz:
https://doaj.org/article/2d1035715dfe4b689a613ea02639b385
Autor:
Thomas Günther, Matthias Konrad, León Stopper, Jan-Philip Kunert, Sebastian Fischer, Roswitha Beck, Angela Casini, Hans-Jürgen Wester
Publikováno v:
Pharmaceuticals, Vol 15, Iss 9, p 1133 (2022)
Current radiolabeled gastrin-releasing peptide receptor (GRPR) ligands usually suffer from high accumulation in GRPR-positive organs (pancreas, stomach), limiting tumor-to-background contrast in the abdomen. In novel N4-bombesin derivatives this was
Externí odkaz:
https://doaj.org/article/9bc62e89658747819f19f6c39ceeedf8
Autor:
Alexander Schmidt, Martina Wirtz, Stefanie Felicitas Färber, Theresa Osl, Roswitha Beck, Margret Schottelius, Markus Schwaiger, Hans-Jürgen Wester
Publikováno v:
ACS Omega, Vol 3, Iss 7, Pp 8278-8287 (2018)
Externí odkaz:
https://doaj.org/article/a7ccc9f004ab43bf9361566b815b6c5d
Autor:
Stefanie Felicitas Färber, Alexander Wurzer, Florian Reichart, Roswitha Beck, Horst Kessler, Hans-Jürgen Wester, Johannes Notni
Publikováno v:
ACS Omega, Vol 3, Iss 2, Pp 2428-2436 (2018)
Externí odkaz:
https://doaj.org/article/c6600f267dd4423f826544713a9d9e9d
Autor:
Vera Russmann, Matthias Brendel, Erik Mille, Angela Helm-Vicidomini, Roswitha Beck, Lisa Günther, Simon Lindner, Axel Rominger, Michael Keck, Josephine D. Salvamoser, Nathalie L. Albert, Peter Bartenstein, Heidrun Potschka
Publikováno v:
NeuroImage: Clinical, Vol 15, Iss , Pp 35-44 (2017)
Excessive activation of inflammatory signaling pathways seems to be a hallmark of epileptogenesis. Positron emission tomography (PET) allows in vivo detection of brain inflammation with spatial information and opportunities for longitudinal follow-up
Externí odkaz:
https://doaj.org/article/007b0bb7e117490195cd2748c970a098