Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Roswith, Eisert"'
Publikováno v:
Klinische Pädiatrie. 224:211-226
To learn more about prioritisation in the health care system, we performed an exploratory qualitative study on haemophilia A. The aim was to generate haemophilia disease-specific criteria and to learn more about reasoning in the decision-making proce
Publikováno v:
Sozialer Fortschritt. 60:73-81
Die aktuelle Debatte um Rationierung oder Priorisierung medizinischer Leistungen beruhrt die Frage nach dem Solidarprinzip der GKV und dem Solidaritatsverstandnis ihrer Versicherten. Der vorliegende Beitrag stellt Ergebnisse einer empirischen Untersu
Autor:
Jürgen Horst, Hartmut Pollmann, Roswith Eisert, Albena Todorova, Marcin Chlystun, Nadja Bogdanova, C. Wermes, Arseni Markoff, Ulrike Nowak-Göttl
Publikováno v:
Human Mutation. 28:54-60
The amount of residual F8 (FVIII:C) determines the clinical severity of hemophilia A. Recently, we showed that the mutation detection rate in severely affected male patients (FVIII:C1% of normal) is virtually 100% when testing for the common intron 2
Autor:
Arseni Markoff, Ulrike Nowak-Göttl, Jürgen Horst, Albena Todorova, Nadja Bogdanova, Bernd Dworniczak, C. Wermes, Hartmut Pollmann, Antonin Eigel, Roswith Eisert
Publikováno v:
Human Mutation. 26:249-254
Hemophilia A is the most frequently occurring X-linked bleeding disorder, affecting one to two out of 10,000 males worldwide. Various types of mutations in the F8 gene are causative for this condition. It is well known that the most common mutation i
Autor:
Arnold Ganser, Silke Ehrenforth, Inge Scharrer, Mario von Depka, Roswith Eisert, Andreas Czwalinna, C. Wermes
Publikováno v:
Thrombosis and Haemostasis. 89:847-852
SummaryACE displays potent vasoconstrictive effects, attenuation of fibrinolysis, and platelet activation and aggregation, thus possibly promoting venous thromboembolism (VTE). The ACE gene contains an insertion (I) or deletion (D) polymorphism accou
Autor:
Arnold Ganser, Ulrike Nowak-Göttl, Monika Barthels, Inge Scharrer, Roswith Eisert, Silke Ehrenforth, Christian Dieterich, Mario von Depka
Publikováno v:
Blood. 96:3364-3368
Elevation of serum lipoprotein (a) (Lp[a]) is a known risk factor predisposing to cardiovascular and cerebrovascular disease. However, little is known about the role of increased Lp(a) in venous thromboembolism (VTE). This study evaluated the role of
Autor:
Roswith Eisert, Christiane De Rop, Arnold Ganser, Arne Trummer, Stefanie Buchholz, Michael B. Stadler
Publikováno v:
Transplantation. 92(3)
Background There is compelling evidence that blood-borne tissue factor that is predominantly found on circulating microparticles (MPs) plays an important role in both, cancer biology and organ and stem-cell transplantation (SCT). Therefore, we hypoth
Publikováno v:
Das Gesundheitswesen. 71
Autor:
Nadja, Bogdanova, Arseni, Markoff, Hartmut, Pollmann, Ulrike, Nowak-Göttl, Roswith, Eisert, Bernd, Dworniczak, Antonin, Eigel, Jürgen, Horst
Publikováno v:
Human mutation. 20(3)
Hemophilia A is a common X-linked bleeding disorder caused by various types of mutations in the factor VIII gene F8C. The most common intron 22-inversion is responsible for about 40% of the severe hemophilia A cases while large deletions, point mutat
Autor:
Silke Ehrenforth, Arnold Ganser, Inge Scharrer, Cornelia Wermes, Roswith Eisert, Andreas Czwalinna, Mario von Depka
Publikováno v:
Thrombosis and haemostasis. 86(6)
Summary Background: The endothelial cell protein C receptor (EPCR) enhances protein C activation by the thrombin-thrombomodulin complex. As evidence is accumulating that EPCR is an important component of the protein C anticoagulant pathway, polymorph