Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Rostock Angelika"'
Autor:
Norbert Höfgen, Klaus Unverferth, Birgit Müller, Andreas Rolfs, Ralf Günther, Jürgen Liebscher, Jürgen Engel, Hans-Jörg Hofmann, Menzer Manfred, Rostock Angelika, Hans-Joachim Lankau
Publikováno v:
Journal of Medicinal Chemistry. 41:63-73
Starting from the corresponding acetophenone and glycine derivatives, a series of new 3-aminopyrroles was synthesized in few steps. Using this procedure with hydrazine and hydroxylamine instead of the glycinates provides access to 3-aminopyrazoles an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d84996869d3cf261135f3dce34056e
https://doi.org/10.1021/jm970327j
https://doi.org/10.1021/jm970327j
Autor:
H. Steve White, Tober Christine, Harold H. Wolf, Rostock Angelika, Reni Bartsch, Chris Rundfeldt, Jürgen Engel, Klaus Unverferth
Publikováno v:
Epilepsy Research. 28:17-28
The anticonvulsant activity of the novel drug AWD 140-190 (4-(p-bromophenyl)-3-morpholino-1H-pyrrole-2-carboxylic acid methyl ester) was evaluated in animal models of epileptic seizures. AWD 140-190 was active at nontoxic doses after oral and intrape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ae12a14cf425dbdd52357ae3c5bee15
https://doi.org/10.1016/s0920-1211(97)00023-5
https://doi.org/10.1016/s0920-1211(97)00023-5
Publikováno v:
Biochemical Pharmacology. 53:135-140
In vitro preincubation of brain membranes of aged mice with piracetam (0.1-1.0 mmol/L) enhanced membrane fluidity, as indicated by decreased anisotropy of the membrane-bound fluorescence probe 1,6-diphenyl-1,3,5-hexatriene (DPH). Piracetam had simila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf44e32f624182f5379019a78ee26841
https://doi.org/10.1016/s0006-2952(96)00463-7
https://doi.org/10.1016/s0006-2952(96)00463-7
Autor:
Hans-Joachim Lankau, Thomas Arnold, Menzer Manfred, Rostock Angelika, Chris Rundfeldt, Klaus Unverferth
Publikováno v:
ChemInform. 30
New 3-amino- and 5-aminopyrazoles were synthesised. 3-Aminopyrazoles exert a strong anticonvulsant effect, 4-Chlorophenyl-3-(morpholin-4-yl)-1 H-pyrazole 2 distinctively blocks sodium channels and is strongly effective in the Maximal Electroshock Sei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4a2c460bbf649d9be3d9c96d5835c1
https://doi.org/10.1002/chin.199935142
https://doi.org/10.1002/chin.199935142
Autor:
Mercedes Salaices, Chi Hin Cho, Oehler J, L. Pénzes, Jesús Marín, Tadahiko Fujino, Kohei Eto, H.-D. Fischer, Jähkel M, Rostock Angelika, C.W. Ogle, K.K. Hui, Yutaka Gomita, G.P. Garg, E. Rudolph, Yasunori Araki, Inmaculada Rico, María J. Alonso, S.E. Borst, Sang S. Park, Katsushi Furuno, Donna West, Ch. Siegemund, M.E. Conolly, Wustmann C, Harry V. Gelboin
Publikováno v:
Pharmacology. 40:I-VI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bd4df84391661b2603d4600293fa9c3f
https://doi.org/10.1159/000138676
https://doi.org/10.1159/000138676
Autor:
Oehler J, Jähkel M, S.E. Borst, Chi Hin Cho, E. Rudolph, C.W. Ogle, Donna West, Yutaka Gomita, Yasunori Araki, Kohei Eto, G.P. Garg, L. Pénzes, Inmaculada Rico, Tadahiko Fujino, Rostock Angelika, K.K. Hui, María J. Alonso, H.-D. Fischer, Sang S. Park, Mercedes Salaices, Katsushi Furuno, Harry V. Gelboin, M.E. Conolly, Ch. Siegemund, Jesús Marín, Wustmann C
Publikováno v:
Pharmacology. 40:351-354
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b87359b90e559555d7924f55dcf48636
https://doi.org/10.1159/000138685
https://doi.org/10.1159/000138685
Autor:
Chris Rundfeldt, Hans-Joachim Lankau, Klaus Unverferth, Thomas Arnold, Menzer Manfred, Rostock Angelika
Publikováno v:
Archiv der Pharmazie. 332(6)
New 3-amino- and 5-aminopyrazoles were synthesised. 3-Aminopyrazoles exert a strong anticonvulsant effect, 4-Chlorophenyl-3-(morpholin-4-yl)-1 H-pyrazole 2 distinctively blocks sodium channels and is strongly effective in the Maximal Electroshock Sei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a52b9570cda72c74dd9f0b151ded90f
https://pubmed.ncbi.nlm.nih.gov/10399492
https://pubmed.ncbi.nlm.nih.gov/10399492
Publikováno v:
European journal of pharmacology. 303(3)
The novel anticonvulsant drug D-23129 (N-(2-amino-4-(4-fluorobenzylamino)-phenyl) carbamic acid ethyl ester) was evaluated in the amygdala kindling model of complex partial seizures in rats. D-23129 exerts potent anticonvulsant activity against both
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa0209dcf1a1b53178e04d4662956156
https://pubmed.ncbi.nlm.nih.gov/8813562
https://pubmed.ncbi.nlm.nih.gov/8813562
Autor:
Dagmar Hönack, Bernhard Kutscher, Rostock Angelika, Jürgen Engel, Harold H. Wolf, Wolfgang Löscher, H. Steve White, Tober Christine, Emanuele E. Polymeropoulos, Chris Rundfeldt, Reni Bartsch
Publikováno v:
Epilepsy research. 23(3)
The anticonvulsant activity of the novel drug D-23129 ( N -(2-amino-4-(4-fluorobenzylamino)phenyl)carbamic acid ethyl ester) was evaluated in animal models of epileptic seizures. D-23129 was active after oral and intraperitoneal administration in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e57fdbf2a71ccdc765ba9cca982d018
https://pubmed.ncbi.nlm.nih.gov/8739124
https://pubmed.ncbi.nlm.nih.gov/8739124
Autor:
E. Rudolph, Ch. Siegemund, Oehler J, Jähkel M, Wustmann C, Rostock Angelika, L. Pénzes, H.-D. Fischer
Publikováno v:
Pharmacology. 40(6)
Male CBA/Ca inbred mice were treated with a dose of 8 micrograms 2-mercapto-ethanol per animal per day in the drinking water from the age of 5 months onwards up to the age of 24 months. Dopamine release was greatly decreased in old animals in contras
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9152b57e57b74ff6bebacd4d6fd684da
https://pubmed.ncbi.nlm.nih.gov/2236202
https://pubmed.ncbi.nlm.nih.gov/2236202