Zobrazeno 1 - 10
of 399
pro vyhledávání: '"Rossner, Steffen"'
Autor:
Moceri, Sandra, Bäuerle, Natascha, Habermeyer, Johanna, Ratz-Wirsching, Veronika, Harrer, Julia, Distler, Jörg, Schulze-Krebs, Anja, Timotius, Ivanna K., Bluhm, Alexandra, Hartlage-Rübsamen, Maike, Roßner, Steffen, Winkler, Jürgen, Xiang, Wei, Hörsten, Stephan von
Parkinson’s disease (PD) is a common neurodegenerative movement disorder, characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta and the accumulation of aggregated alpha synuclein (aSyn). The disease often presents
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A94161
https://ul.qucosa.de/api/qucosa%3A94161/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A94161/attachment/ATT-0/
Autor:
Tindall, Catherine A., Möhlis, Kevin, Rapöhn, Inka, Dommel, Sebastian, Riedl, Veronika, Schneekönig, Michael, Höfling, Corinna, Roßner, Steffen, Stichel, Jan, Beck-Sickinger, Annette G., Weiner, Juliane, Heiker, John T.
Vaspin is a serine protease inhibitor that protects against adipose tissueinflammation and insulin resistance, two key drivers of adipocyte dysfunc-tion and metabolic disorders in obesity. Inhibition of target proteases suchas KLK7 has been shown to
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A94162
https://ul.qucosa.de/api/qucosa%3A94162/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A94162/attachment/ATT-0/
Autor:
Barendrecht, Susan, Schreurs, An, Geissler, Stefanie, Sabanov, Victor, Ilse, Victoria, Rieckmann, Vera, Eichentopf, Rico, Künemund, Anja, Hietel, Benjamin, Wussow, Sebastian, Hoffmann, Katrin, Körber‑Ferl, Kerstin, Pandey, Ravi, Carter, Gregory W., Demuth, Hans‑Ulrich, Holzer, Max, Roßner, Steffen, Schilling, Stephan, Preuss, Christoph, Balschun, Detlef, Cynis, Holger
Background Hyperphosphorylation and intraneuronal aggregation of the microtubule-associated protein tau is a major pathological hallmark of Alzheimer’s disease (AD) brain. Of special interest is the effect of cerebral amyloid beta deposition, the s
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93546
https://ul.qucosa.de/api/qucosa%3A93546/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A93546/attachment/ATT-0/
Autor:
Grochowska, Katarzyna M., Gomes, Guilherme M., Raman, Rajeev, Kaushik, Rahul, Sosulina, Liudmila, Kaneko, Hiroshi, Oelschlegel, Anja M., Yuanxiang, PingAn, Reyes-Resina, Irene, Bayraktar, Gonca, Samer, Sebastian, Spilker, Christina, Woo, Marcel S, Morawski, Markus, Goldschmidt, Jürgen, Friese, Manuel A., Rossner, Steffen, Navarro, Gemma, Remy, Stefan, Reissner, Carsten, Karpova, Anna, Kreutz, Michael R
Synaptic dysfunction caused by soluble β-amyloid peptide (Aβ) is a hallmark of early-stage Alzheimer's disease (AD), and is tightly linked to cognitive decline. By yet unknown mechanisms, Aβ suppresses the transcriptional activity of cAMP-responsi
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93551
https://ul.qucosa.de/api/qucosa%3A93551/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A93551/attachment/ATT-0/
Autor:
Höfling, Corinna, Roßner, Steffen, Flachmeyer, Bianca, Krueger, Martin, Härtig, Wolfgang, Michalski, Dominik
Along with initiatives to understand the pathophysiology of stroke in detail and to identify neuroprotective targets, cell-stabilizing elements have gained increasing attention. Although cell culture experiments have indicated that tricellulin, α-ca
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A93506
https://ul.qucosa.de/api/qucosa%3A93506/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A93506/attachment/ATT-0/
Autor:
Bluhm, Alexandra, Schrempel, Sarah, Moceri, Sandra, Stieler, Jens, Feja, Malte, Schilling, Stephan, Schulze, Anja, Hörsten, Stephan von, Hartlage-Rübsamen, Maike, Richter, Franziska, Roßner, Steffen
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A94404
https://ul.qucosa.de/api/qucosa%3A94404/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A94404/attachment/ATT-0/
Autor:
Ilse, Victoria, Scholz, Rebekka, Wermann, Michael, Naumann, Marcel, Staege, Martin S., Roßner, Steffen, Cynis, Holger
The triggers for the development of multiple sclerosis (MS) have not been fully understood to date. One hypothesis proposes a viral etiology. Interestingly, viral proteins from human endogenous retroviruses (HERVs) may play a role in the pathogenesis
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A89174
https://ul.qucosa.de/api/qucosa%3A89174/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A89174/attachment/ATT-0/
Autor:
Bluhm, Alexandra, Schrempel, Sarah, Schilling, Stephan, von Hörsten, Stephan, Schulze, Anja, Roßner, Steffen, Hartlage-Rübsamen, Maike
The deposition of β-amyloid peptides and of α-synuclein proteins is a neuropathological hallmark in the brains of Alzheimer’s disease (AD) and Parkinson’s disease (PD) subjects, respectively. However, there is accumulative evidence that both pr
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A87883
https://ul.qucosa.de/api/qucosa%3A87883/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A87883/attachment/ATT-0/
Neurodegenerative disorders including Parkinson’s disease (PD), Huntington’s disease (HD) and the most frequent, Alzheimer’s disease (AD), represent one of the most urgent medical needs worldwide. Despite a significantly developed understanding
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A87377
https://ul.qucosa.de/api/qucosa%3A87377/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A87377/attachment/ATT-0/
Autor:
Kara, Firat, Belloy, Michael E., Voncken, Rick, Sarwari, Zahra, Garima, Yadav, Anckaerts, Cynthia, Langbeen, An, Leysen, Valerie, Shah, Disha, Jacobs, Jules, Hamaide, Julie, Bols, Peter, Audekerke, Johan Van, Daans, Jasmijn, Guglielmetti, Caroline, Kantarci, Kejal, Prevot, Vincent, Roßner, Steffen, Ponsaerts, Peter, Linden, Annemie Van der, Verhoye, Marleen
Premenopausal bilateral ovariectomy is considered to be one of the risk factors of Alzheimer's disease (AD). However, the underlying mechanisms remain unclear. Here, we aimed to investigate long-term neurological consequences of ovariectomy in a rode
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A94399
https://ul.qucosa.de/api/qucosa%3A94399/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A94399/attachment/ATT-0/