Joint Analysis of Psychiatric Disorders Increases Accuracy of Risk Prediction for Schizophrenia, Bipolar Disorder, and Major Depressive Disorder

Autor: Absher, Devin, Agartz, Ingrid, Akil, Huda, Amin, Farooq, Andreassen, Ole A., Anjorin, Adebayo, Anney, Richard, Arking, Dan E., Asherson, Philip, Azevedo, Maria H., Backlund, Lena, Badner, Judith A., Bailey, Anthony J., Banaschewski, Tobias, Barchas, Jack D., Barnes, Michael R., Barrett, Thomas B., Bass, Nicholas, Battaglia, Agatino, Bauer, Michael, Bayés, Mònica, Bellivier, Frank, Bergen, Sarah E., Berrettini, Wade, Betancur, Catalina, Bettecken, Thomas, Biederman, Joseph, Binder, Elisabeth B., Black, Donald W., Blackwood, Douglas H.R., Bloss, Cinnamon S., Boehnke, Michael, Boomsma, Dorret I., Breen, Gerome, Breuer, René, Bruggeman, Richard, Buccola, Nancy G., Buitelaar, Jan K., Bunney, William E., Buxbaum, Joseph D., Byerley, William F., Caesar, Sian, Cahn, Wiepke, Cantor, Rita M., Casas, Miguel, Chakravarti, Aravinda, Chambert, Kimberly, Choudhury, Khalid, Cichon, Sven, Cloninger, C. Robert, Collier, David A., Cook, Edwin H., Coon, Hilary, Cormand, Bru, Cormican, Paul, Corvin, Aiden, Coryell, William H., Craddock, Nicholas, Craig, David W., Craig, Ian W., Crosbie, Jennifer, Cuccaro, Michael L., Curtis, David, Czamara, Darina, Daly, Mark J., Datta, Susmita, Dawson, Geraldine, Day, Richard, De Geus, Eco J., Degenhardt, Franziska, Devlin, Bernie, Djurovic, Srdjan, Donohoe, Gary J., Doyle, Alysa E., Duan, Jubao, Dudbridge, Frank, Duketis, Eftichia, Ebstein, Richard P., Edenberg, Howard J., Elia, Josephine, Ennis, Sean, Etain, Bruno, Fanous, Ayman, Faraone, Stephen V., Farmer, Anne E., Ferrier, I. Nicol, Flickinger, Matthew, Fombonne, Eric, Foroud, Tatiana, Frank, Josef, Franke, Barbara, Fraser, Christine, Freedman, Robert, Freimer, Nelson B., Freitag, Christine M., Friedl, Marion, Frisén, Louise, Gallagher, Louise, Gejman, Pablo V., Georgieva, Lyudmila, Gershon, Elliot S., Geschwind, Daniel H., Giegling, Ina, Gill, Michael, Gordon, Scott D., Gordon-Smith, Katherine, Green, Elaine K., Greenwood, Tiffany A., Grice, Dorothy E., Gross, Magdalena, Grozeva, Detelina, Guan, Weihua, Gurling, Hugh, De Haan, Lieuwe, Haines, Jonathan L., Hakonarson, Hakon, Hallmayer, Joachim, Hamilton, Steven P., Hamshere, Marian L., Hansen, Thomas F., Hartmann, Annette M., Hautzinger, Martin, Heath, Andrew C., Henders, Anjali K., Herms, Stefan, Hickie, Ian B., Hipolito, Maria, Hoefels, Susanne, Holmans, Peter A., Holsboer, Florian, Hoogendijk, Witte J., Hottenga, Jouke-Jan, Hultman, Christina M., Hus, Vanessa, Ingason, Andrés, Ising, Marcus, Jamain, Stéphane, Jones, Ian, Jones, Lisa, Kähler, Anna K., Kahn, René S., Kandaswamy, Radhika, Keller, Matthew C., Kelsoe, John R., Kendler, Kenneth S., Kennedy, James L., Kenny, Elaine, Kent, Lindsey, Kim, Yunjung, Kirov, George K., Klauck, Sabine M., Klei, Lambertus, Knowles, James A., Kohli, Martin A., Koller, Daniel L., Konte, Bettina, Korszun, Ania, Krabbendam, Lydia, Krasucki, Robert, Kuntsi, Jonna, Kwan, Phoenix, Landén, Mikael, Långström, Niklas, Lathrop, Mark, Lawrence, Jacob, Lawson, William B., Leboyer, Marion, Ledbetter, David H., Lee, Phil H., Lencz, Todd, Lesch, Klaus-Peter, Levinson, Douglas F., Lewis, Cathryn M., Li, Jun, Lichtenstein, Paul, Lieberman, Jeffrey A., Lin, Dan-Yu, Linszen, Don H., Liu, Chunyu, Lohoff, Falk W., Loo, Sandra K., Lord, Catherine, Lowe, Jennifer K., Lucae, Susanne, MacIntyre, Donald J., Madden, Pamela A.F., Maestrini, Elena, Magnusson, Patrik K.E., Mahon, Pamela B., Maier, Wolfgang, Malhotra, Anil K., Mane, Shrikant M., Martin, Christa L., Martin, Nicholas G., Mattheisen, Manuel, Matthews, Keith, Mattingsdal, Morten, McCarroll, Steven A., McGhee, Kevin A., McGough, James J., McGrath, Patrick J., McGuffin, Peter, McInnis, Melvin G., McIntosh, Andrew, McKinney, Rebecca, McLean, Alan W., McMahon, Francis J., McMahon, William M., McQuillin, Andrew, Medeiros, Helena, Medland, Sarah E., Meier, Sandra, Melle, Ingrid, Meng, Fan, Meyer, Jobst, Middeldorp, Christel M., Middleton, Lefkos, Milanova, Vihra, Miranda, Ana, Monaco, Anthony P., Montgomery, Grant W., Moran, Jennifer L., Moreno-De-Luca, Daniel, Morken, Gunnar, Morris, Derek W., Morrow, Eric M., Moskvina, Valentina, Mowry, Bryan J., Muglia, Pierandrea, Mühleisen, Thomas W., Müller-Myhsok, Bertram, Murtha, Michael, Myers, Richard M., Myin-Germeys, Inez, Neale, Benjamin M., Nelson, Stan F., Nievergelt, Caroline M., Nikolov, Ivan, Nimgaonkar, Vishwajit, Nolen, Willem A., Nöthen, Markus M., Nurnberger, John I., Nwulia, Evaristus A., Nyholt, Dale R., O’Donovan, Michael C., O’Dushlaine, Colm, Oades, Robert D., Olincy, Ann, Oliveira, Guiomar, Olsen, Line, Ophoff, Roel A., Osby, Urban, Owen, Michael J., Palotie, Aarno, Parr, Jeremy R., Paterson, Andrew D., Pato, Carlos N., Pato, Michele T., Penninx, Brenda W., Pergadia, Michele L., Pericak-Vance, Margaret A., Perlis, Roy H., Pickard, Benjamin S., Pimm, Jonathan, Piven, Joseph, Posthuma, Danielle, Potash, James B., Poustka, Fritz, Propping, Peter, Purcell, Shaun M., Puri, Vinay, Quested, Digby J., Quinn, Emma M., Ramos-Quiroga, Josep Antoni, Rasmussen, Henrik B., Raychaudhuri, Soumya, Rehnström, Karola, Reif, Andreas, Ribasés, Marta, Rice, John P., Rietschel, Marcella, Ripke, Stephan, Roeder, Kathryn, Roeyers, Herbert, Rossin, Lizzy, Rothenberger, Aribert, Rouleau, Guy, Ruderfer, Douglas, Rujescu, Dan, Sanders, Alan R., Sanders, Stephan J., Santangelo, Susan L., Schachar, Russell, Schalling, Martin, Schatzberg, Alan F., Scheftner, William A., Schellenberg, Gerard D., Scherer, Stephen W., Schork, Nicholas J., Schulze, Thomas G., Schumacher, Johannes, Schwarz, Markus, Scolnick, Edward, Scott, Laura J., Sergeant, Joseph A., Shi, Jianxin, Shilling, Paul D., Shyn, Stanley I., Silverman, Jeremy M., Sklar, Pamela, Slager, Susan L., Smalley, Susan L., Smit, Johannes H., Smith, Erin N., Smoller, Jordan W., Sonuga-Barke, Edmund J.S., St Clair, David, State, Matthew, Steffens, Michael, Steinhausen, Hans-Christoph, Strauss, John S., Strohmaier, Jana, Stroup, T. Scott, Sullivan, Patrick F., Sutcliffe, James, Szatmari, Peter, Szelinger, Szabocls, Thapar, Anita, Thirumalai, Srinivasa, Thompson, Robert C., Todorov, Alexandre A., Tozzi, Federica, Treutlein, Jens, Tzeng, Jung-Ying, Uhr, Manfred, van den Oord, Edwin J.C.G., Van Grootheest, Gerard, Van Os, Jim, Vicente, Astrid M., Vieland, Veronica J., Vincent, John B., Visscher, Peter M., Walsh, Christopher A., Wassink, Thomas H., Watson, Stanley J., Weiss, Lauren A., Weissman, Myrna M., Werge, Thomas, Wienker, Thomas F., Wiersma, Durk, Wijsman, Ellen M., Willemsen, Gonneke, Williams, Nigel, Willsey, A. Jeremy, Witt, Stephanie H., Wray, Naomi R., Xu, Wei, Young, Allan H., Yu, Timothy W., Zammit, Stanley, Zandi, Peter P., Zhang, Peng, Zitman, Frans G., Zöllner, Sebastian, Maier, Robert, Moser, Gerhard, Chen, Guo-Bo, Coryell, William, Lee, S. Hong

Publikováno v: In The American Journal of Human Genetics 5 February 2015 96(2):283-294

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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways

Autor: Anita Thapar, Lena Backlund, Lindsey Kent, Walter J. Muir, A. Jeremy Willsey, Sandra K. Loo, Michael Boehnke, Christa Lese Martin, Ania Korszun, Guiomar Oliveira, Veronica J. Vieland, Stephen W. Scherer, René S. Kahn, Darina Czamara, Jeremy R. Parr, Michael E. Goddard, Willem A. Nolen, Josep Antoni Ramos-Quiroga, Stephen Sanders, Karola Rehnstroem, Nelson B. Freimer, Erin N. Smith, Ann Olincy, Ingrid Melle, Myrna M. Weissman, James A. Knowles, William Byerley, Aravinda Chakravarti, Shaun Purcell, Jens Treutlein, Sebastian Zoellner, Hakon Hakonarson, Susanne Lucae, Markus M. Noethen, Ian B. Hickie, Marion Friedl, Srinivasa Thirumalai, Stephen Newhouse, Joseph Piven, Andrew M. McIntosh, Cathryn M. Lewis, Srdjan Djurovic, Francis J. McMahon, Ayman H. Fanous, Bernie Devlin, Steven A. McCarroll, Alan F. Schatzberg, Peter Szatmari, Marta Ribasés, C. Robert Cloninger, Brenda W.J.H. Penninx, Gerard van Grootheest, Phil Lee, Richard Anney, Elaine K. Green, Geraldine Dawson, Joseph A. Sergeant, Digby Quested, Magdalena Gross, Jack D. Barchas, Nicholas G. Martin, Timothy W. Yu, Jouke-Jan Hottenga, Mark Lathrop, Federica Tozzi, Martin Hautzinger, Alysa E. Doyle, Cinnamon S. Bloss, Sandra Meier, Louise Gailagher, David A. Collier, Farooq Amin, Michael C. Neale, Martin Schalling, Lieuwe de Haan, Bru Cormand, Falk W. Lohoff, Jennifer Crosbie, Howard J. Edenberg, Aarno Palotie, Johannes H. Smit, Robert Freedman, Katherine Gordon-Smith, Michele L. Pergadia, Enda M. Byrne, Hans-Christoph Steinhausen, Benjamin M. Neale, Anjali K. Henders, Michele T. Pato, Manuel Mattheisen, Urban Ösby, Edward M. Scolnick, Evaristus A. Nwulia, Fritz Poustka, Gonneke Willemsen, Andrew C. Heath, David St. Cair, Emma M. Quinn, I. Nicol Ferrier, John R. Kelsoe, Vanessa Hus, Andrew McQuillin, John P. Rice, William M. McMahon, Joseph Biederman, Danyu Lin, Wolfgang Maier, Frans G. Zitman, Josephine Elia, Nicholas J. Schork, Stéphane Jamain, Lizzy Rossin, Jubao Duan, Ingrid Agartz, Devin Absher, Jordan W. Smoller, Matthew W. State, Richard M. Myers, Shrikant Mane, Carlos N. Pato, William E. Bunney, Marian L. Hamshere, Manfred Uhr, Nicholas John Craddock, Astrid M. Vicente, Tobias Banaschewski, David Curtis, Anne Farmer, Scott D. Gordon, Anna K. Kaehler, Eric M. Morrow, Marcella Rietschel, Patrik K. E. Magnusson, Klaus-Peter Lesch, Rebecca McKinney, Jana Strohmaier, Thomas F. Wienker, Pablo V. Gejman, Douglas Blackwood, Maria Helena Pinto de Azevedo, Tiffany A. Greenwood, Don H. Linszen, Daniel L. Koller, Richard Bruggeman, Vinay Puri, Naomi R. Wray, Stanley J. Watson, Elena Maestrini, Valentina Moskvina, Frank Dudbridge, Danielle Posthuma, Edward G. Jones, Lambertus Klei, Sarah E. Bergen, Fan Meng, Steven P. Hamilton, Guy A. Rouleau, Pierandrea Muglia, Mikael Landén, Stephanie H. Witt, Laramie E. Duncan, Stanley Zammit, Judith A. Badner, Florian Holsboer, Eco J. 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Ophoff, Peter McGuffin, Stefan Herms, Bettina Konte, George Kirov, Hilary Coon, Maria Hipolito, Louise Frisén, Kenneth S. Kendler, Frank Bellivier, James S. Sutdiffe, Jeffrey A. Lieberman, Todd Lencz, Susanne Hoefels, Alan W. McLean, Barbara Franke, Huda Akil, Soumya Raychaudhuri, Ellen M. Wijsman, Vishwajit L. Nimgaonkar, Roy H. Perlis, Patrick J. McGrath, Susan L. Santangelo, William Coryell, Henrik B. Rasmussen, Weihua Guan, William Lawson, Elliot S. Gershon, Sean Ennis, Aiden Corvin, Allan H. Young, Thomas B. Barrett, Jonathan L. Haines, Douglas F. Levinson, Ana Miranda, Anil K. Malhotra, S. Hong Lee, Stan F. Nelson, Anthony J. Bailey, Patrick F. Sullivan, Dorothy E. Grice, Lefkos T. Middleton, Bertram Mueller-Myhsok, Michael R. Barnes, Adebayo Anjorin

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Network and Pathway Analysis Subgroup of the Psychiatric Genomics Consortium 2015, ' Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways ', Nature Neuroscience, vol. 18, no. 2, pp. 199-209 . https://doi.org/10.1038/nn.3922
Nature Neuroscience
Nature Neuroscience, Nature Publishing Group, 2015, 18 (2), pp.199-209. ⟨10.1038/nn.3922⟩
Nature Neuroscience, 18, 199-209
Nature Neuroscience, 18(2), 199-209. Nature Publishing Group
Nature Neuroscience, 18(2), 199-209
O’Dushlaine, C, Rossin, L, Lee, P H, Duncan, L, Parikshak, N N, Newhouse, S, Ripke, S, Neale, B M, Purcell, S M, Posthuma, D, Boomsma, D I, de Geus, E J C, Hottenga, J J, Krabbendam, A C, Middeldorp, C M, Penninx, B W J H, Sergeant, J A, Smit, J H, Grootheest, G, Willemsen, G, Holmes, P & Breen, G 2015, ' Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways ', Nature Neuroscience, vol. 18, no. 2, pp. 199-209 . https://doi.org/10.1038/nn.3922
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Nature neuroscience, vol 18, iss 2
Nature neuroscience, 18(2), 199-209. Nature Publishing Group
Recercat. Dipósit de la Recerca de Catalunya
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Nature Neuroscience, 18, 2, pp. 199-209
Nature neuroscience, 18(2), 199-209. NATURE AMERICA INC
O'Dushlaine, C, Rossin, L, Lee, P H, Duncan, L, Parikshak, N N, Newhouse, S, Ripke, S, Neale, B M, Purcell, S M, Posthuma, D, Nurnberger, J I, Lee, S H, Faraone, S V, Perlis, R H, Mowry, B J, Thapar, A, Goddard, M E, Witte, J S, Absher, D, Agartz, I, Akil, H, Amin, F, Andreassen, O A, Anjorin, A, Anney, R, Anttila, V, Arking, D E, Asherson, P, Azevedo, M H, Backlund, L, Badner, J A, Bailey, A J, Banaschewski, T, Barchas, J D, Barnes, M R, Barrett, T B, Bass, N, Battaglia, A, Bauer, M, Bayes, M, Bellivier, F, Bergen, S E, Berrettini, W, Betancur, C, Bettecken, T, Biederman, J, Binder, E B, Black, D W, Mattheisen, M, Meier, S, IIBDGC & Network & Pathway Anal Subgrp Psyc 2015, ' Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways ', Nature Neuroscience, vol. 18, no. 2, pp. 199-209 . https://doi.org/10.1038/nn.3922
Nature Neuroscience, 2015, 18 (2), pp.199-209. ⟨10.1038/nn.3922⟩
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Universidad de Barcelona

G.B. and S.N. acknowledge funding support for this work from the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. P.H.L. is supported b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe26241cfa978b89471038385188346d
https://hdl.handle.net/1887/101566