Initiation, propagation and resolution of inflammation

Autor: Rossi, Adriano Giorgio

In order to gain a better understanding of the mechanisms controlling inflammatory processes with a view to developing novel therapies for inflammatory disease, the research presented in this thesis has been focused on unravelling the molecular compl

Externí odkaz: https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.726427

Dysregulation of prostaglandins, leukotrienes and lipoxin A4 in bronchiectasis

Autor: Bedi, Pallavi, Ziegler, Kerstin, Whitfield, Phil D., Davidson, Donald, Rossi, Adriano Giorgio, Hill, Adam T.

Introduction: Bronchiectasis is characterised by excessive neutrophilic inflammation. Lipid mediators such as prostaglandins and leukotrienes have crucial roles in the inflammatory response. Further characterisation of these lipids and understanding

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::5ad435858c1d90356467d8ae9e37b20c
https://eprints.gla.ac.uk/259339/1/259339.pdf

Alternatively activated macrophages promotes necrosis resolution following acute liver injury

Autor: Starkey Lewis, Philip, Campana, Lara, Aleksieva, Niya, Cartwright, Jennifer Ann, Mackinnon, Alison, O'Duibhir, Eoghan, Kendall, Tim, Vermeren, Matthieu, Thomson, Adrian, Gadd, Victoria, Dwyer, Benjamin, Aird, Rhona, Man, Tak-Yung, Rossi, Adriano Giorgio, Forrester, Lesley, Park, B. Kevin, Forbes, Stuart John

Publikováno v: Starkey Lewis, P, Campana, L, Aleksieva, N, Cartwright, J A, Mackinnon, A, O'Duibhir, E, Kendall, T, Vermeren, M, Thomson, A, Gadd, V, Dwyer, B, Aird, R, Man, T-Y, Rossi, A G, Forrester, L, Park, B K & Forbes, S J 2020, ' Alternatively activated macrophages promotes necrosis resolution following acute liver injury ', Journal of Hepatology, vol. 73, no. 2, pp. 349-360 . https://doi.org/10.1016/j.jhep.2020.02.031

Background & Aim: Acute liver injury (ALI) can occur if a significant acetaminophen (APAP) overdose presents too late for n-acetylcysteine treatment, which risks deterioration into acute liver failure, systemic inflammation, and death. Macrophages in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3094::36fd4bc5f65cdc9d66bde3d1e177df33
https://hdl.handle.net/20.500.11820/04cd9502-b744-4b3a-9eb0-1674f5043782

Early PREdiction of Severe Sepsis (ExPRES-Sepsis) study: protocol for an observational derivation study to discover potential leucocyte cell surface biomarkers

Autor: Datta, Deepankar, Conway Morris, Andrew, Antonelli, Jean, Warner, Noel, Brown, Kenneth Alun, Wright, John, Simpson, A John, Rennie, Jillian, Hulme, Gillian, Lewis, Sion Marc, Mare, Tracey Anne, Cookson, Sharon, Weir, Christopher John, Dimmick, Ian, Keenan, Jim, Rossi, Adriano Giorgio, Shankar-Hari, Manu, Walsh, Timothy S, ExPRES Sepsis Investigators

INTRODUCTION: Sepsis is an acute illness resulting from infection and the host immune response. Early identification of individuals at risk of developing life-threatening severe sepsis could enable early triage and treatment, and improve outcomes. Cu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47ce62afd29befba487e43185b09f26f

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