TINC - a method to dissect transcriptional complexes at single locus resolution - reveals novel Nanog regulators in mouse embryonic stem cells

Autor: Knaupp, AS, Mohenska, M, Larcombe, MR, Ford, E, Lim, SM, Wong, K, Chen, J, Firas, J, Huang, C, Liu, X, Nguyen, T, Sun, YBY, Holmes, ML, Tripathi, P, Rossello, FJ, Schröder, J, Nefzger, CM, Das, PP, Haigh, JJ, Lister, R, Schittenhelm, RB, Polo, JM

Cellular identity is ultimately controlled by transcription factors (TFs), which bind to specific regulatory elements (REs) within the genome to regulate gene expression and cell fate changes. While recent advances in genome-wide epigenetic profiling

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46b0762af213a00bbc68f1781594c046
https://doi.org/10.1101/2020.04.03.023200

Author Correction: A placental model of SARS-CoV-2 infection reveals ACE2-dependent susceptibility and differentiation impairment in syncytiotrophoblasts.

Autor: Chen J; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Neil JA; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Tan JP; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Rudraraju R; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia., Mohenska M; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Sun YBY; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Walters E; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.; Adelaide Centre for Epigenetics, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Bediaga NG; Adelaide Centre for Epigenetics, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia., Sun G; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Zhou Y; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia., Li Y; Implantation and Pregnancy Research Laboratory, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia., Drew D; Infectious Diseases and Immune Defences Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia., Pymm P; Infectious Diseases and Immune Defences Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia., Tham WH; Infectious Diseases and Immune Defences Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia., Wang Y; Implantation and Pregnancy Research Laboratory, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia., Rossello FJ; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia.; University of Melbourne Centre for Cancer Research, The University of Melbourne, Melbourne, Victoria, Australia., Nie G; Implantation and Pregnancy Research Laboratory, School of Health and Biomedical Sciences, RMIT University, Melbourne, Victoria, Australia., Liu X; School of Life Sciences, Westlake University, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Westlake Institute for Advanced Study, Hangzhou, China., Subbarao K; Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia. kanta.subbarao@influenzacentre.org.; WHO Collaborating Centre for Reference and Research on Influenza, Melbourne, Victoria, Australia. kanta.subbarao@influenzacentre.org., Polo JM; Department of Anatomy and Developmental Biology, Monash University, Clayton, Victoria, Australia. jose.polo@monash.edu.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Clayton, Victoria, Australia. jose.polo@monash.edu.; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia. jose.polo@monash.edu.; Adelaide Centre for Epigenetics, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia. jose.polo@monash.edu.; South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia. jose.polo@monash.edu.

Publikováno v: Nature cell biology [Nat Cell Biol] 2024 Feb; Vol. 26 (2), pp. 305.

The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in Staphylococcus aureus .

Autor: Sharkey LKR; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Guerillot R; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Walsh CJ; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Turner AM; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Lee JYH; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Neville SL; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Klatt S; The Florey Institute of Neuroscience and Mental Health, Melbourne Dementia Research Centre, The University of Melbourne, Parkville, Victoria, Australia., Baines SL; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Pidot SJ; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Rossello FJ; University of Melbourne Centre for Cancer Research, The University of Melbourne, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Seemann T; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Department of Microbiology and Immunology, Centre for Pathogen Genomics, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., McWilliam HEG; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Cho E; Biological Optical Microscopy Platform, University of Melbourne, Melbourne, Victoria, Australia., Carter GP; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Howden BP; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Department of Microbiology and Immunology, Centre for Pathogen Genomics, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., McDevitt CA; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Hachani A; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Stinear TP; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.; Department of Microbiology and Immunology, Centre for Pathogen Genomics, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia., Monk IR; Department of Microbiology and Immunology, Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.

Publikováno v: MBio [mBio] 2023 Dec 19; Vol. 14 (6), pp. e0226223. Date of Electronic Publication: 2023 Oct 16.

Transient naive reprogramming corrects hiPS cells functionally and epigenetically.

Autor: Buckberry S; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.; Telethon Kids Institute, Perth, Western Australia, Australia.; John Curtin School of Medical Research, College of Health and Medicine, Australian National University, Canberra, Australian Capital Territory, Australia., Liu X; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia.; School of Life Sciences, Westlake University, Hangzhou, China.; Research Center for Industries of the Future, Westlake University, Hangzhou, China.; Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, China.; Westlake Institute for Advanced Study, Hangzhou, China., Poppe D; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia., Tan JP; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Sun G; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Chen J; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Nguyen TV; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia., de Mendoza A; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia.; School of Biological and Behavioural Sciences, Queen Mary University of London, London, UK., Pflueger J; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia., Frazer T; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia., Vargas-Landín DB; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia., Paynter JM; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Smits N; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia., Liu N; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Ouyang JF; Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore., Rossello FJ; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia.; Murdoch Children's Research Institute, Melbourne, Victoria, Australia., Chy HS; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia.; Biomedical Manufacturing, Commonwealth Scientific and Industrial Research Organisation, Melbourne, Victoria, Australia., Rackham OJL; Program in Cardiovascular and Metabolic Disorders, Duke-National University of Singapore Medical School, Singapore, Singapore.; School of Biological Sciences, University of Southampton, Southampton, UK., Laslett AL; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia.; Biomedical Manufacturing, Commonwealth Scientific and Industrial Research Organisation, Melbourne, Victoria, Australia., Breen J; John Curtin School of Medical Research, College of Health and Medicine, Australian National University, Canberra, Australian Capital Territory, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Faulkner GJ; Mater Research Institute, University of Queensland, Brisbane, Queensland, Australia.; Queensland Brain Institute, University of Queensland, Brisbane, Queensland, Australia., Nefzger CM; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Polo JM; Department of Anatomy and Developmental Biology, Monash University, Melbourne, Victoria, Australia. jose.polo@monash.edu.; Development and Stem Cells Program, Monash Biomedicine Discovery Institute, Melbourne, Victoria, Australia. jose.polo@monash.edu.; Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia. jose.polo@monash.edu.; Adelaide Centre for Epigenetics, School of Biomedicine, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia. jose.polo@monash.edu.; The South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia. jose.polo@monash.edu., Lister R; Harry Perkins Institute of Medical Research, QEII Medical Centre and Centre for Medical Research, The University of Western Australia, Perth, Western Australia, Australia. ryan.lister@uwa.edu.au.; ARC Centre of Excellence in Plant Energy Biology, School of Molecular Sciences, The University of Western Australia, Perth, Western Australia, Australia. ryan.lister@uwa.edu.au.

Publikováno v: Nature [Nature] 2023 Aug; Vol. 620 (7975), pp. 863-872. Date of Electronic Publication: 2023 Aug 16.

Single-nuclei and bulk-tissue gene-expression analysis of pheochromocytoma and paraganglioma links disease subtypes with tumor microenvironment.

Autor: Zethoven M; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Martelotto L; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Pattison A; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Bowen B; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Balachander S; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Flynn A; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Rossello FJ; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Hogg A; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Miller JA; Department of Surgery, Royal Melbourne Hospital, Parkville, VIC, Australia.; Department of Surgery, Epworth Hospital, Richmond, VIC, Australia., Frysak Z; 3rd Department of Internal Medicine - Nephrology, Rheumatology and Endocrinology, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Olomouc, Czech Republic., Grimmond S; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia., Fishbein L; Department of Medicine, Division of Endocrinology, Metabolism, Diabetes, University of Colorado, Aurora, CO, USA., Tischler AS; Tufts Medical Centre, Boston, MA, USA., Gill AJ; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.; Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia.; NSW Health Pathology, Department of Anatomical Pathology, Royal North Shore Hospital, Sydney, NSW, Australia., Hicks RJ; Peter MacCallum Cancer Centre, Melbourne, VIC, Australia., Dahia PLM; Div. Hematology and Medical Oncology, Department of Medicine, Mays Cancer Center, University of Texas Health Science Center at San Antonio (UTHSCSA), San Antonio, TX, USA., Clifton-Bligh R; Sydney Medical School, University of Sydney, Sydney, NSW, Australia.; Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia., Pacak K; Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, MD, USA., Tothill RW; Centre for Cancer Research and Department of Clinical Pathology, University of Melbourne, Melbourne, VIC, Australia. rtothill@unimelb.edu.au.; Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, VIC, Australia. rtothill@unimelb.edu.au.

Publikováno v: Nature communications [Nat Commun] 2022 Oct 21; Vol. 13 (1), pp. 6262. Date of Electronic Publication: 2022 Oct 21.