Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Rossella Graffeo"'
Autor:
Eleonora Pagan, Monica Ruggeri, Nadia Bianco, Eraldo Oreste Bucci, Rossella Graffeo, Markus Borner, Monica Giordano, Lorenzo Gianni, Manuela Rabaglio, Andrea Freschi, Elisabetta Cretella, Elena Seles, Alberto Farolfi, Edda Simoncini, Mariangela Ciccarese, Daniel Rauch, Adolfo Favaretto, Friedemann Honecker, Rossana Berardi, Alessandra Franzetti-Pellanda, Shari Gelber, Ann H. Partridge, Aron Goldhirsch, Vincenzo Bagnardi, Olivia Pagani, Karin Ribi
Publikováno v:
Breast, Vol 77, Iss , Pp 103765- (2024)
Purpose: Although younger age has been negatively associated with persistence to adjuvant endocrine therapy (ET), factors contributing to non-persistence remain poorly understood. We assessed factors associated with non-persistence to ET and describe
Externí odkaz:
https://doaj.org/article/570c5e4f78064981bd0ebc4df466fd94
Autor:
Vasiliki Baroutsou, Vu Duong, Alice Signorini, Ramon Saccilotto, Florina M. Ciorba, Nicole Bürki, Maria Caiata-Zufferey, Jai Min Ryu, Sung-Won Kim, Myong Cheol Lim, Christian Monnerat, Ursina Zürrer-Härdi, Jisun Kim, Karl Heinimann, Rossella Graffeo, Ji Soo Park, Manuela Rabaglio, Pierre Olivier Chappuis, Sue Kim, Maria C. Katapodi, on behalf of the CASCADE and K-CASCADE Consortia
Publikováno v:
Cancers, Vol 15, Iss 18, p 4485 (2023)
The study adapted the Family Gene Toolkit and developed a customized web application for Swiss and Korean families harboring BRCA1 or BRCA2 pathogenic variants to support family communication of genetic testing results and promote cascade genetic tes
Externí odkaz:
https://doaj.org/article/3fa0bdce511e4aaf99be19514a194563
Autor:
Maria Luisa Gasparri, Rosa Di Micco, Veronica Zuber, Katayoun Taghavi, Giampaolo Bianchini, Serena Bellaminutti, Francesco Meani, Rossella Graffeo, Massimo Candiani, Michael D. Mueller, Andrea Papadia, Oreste D. Gentilini
Publikováno v:
Breast, Vol 60, Iss , Pp 155-162 (2021)
Introduction: Preliminary clinical evidence suggests a detrimental effect of pathogenic variants of BRCA1 and 2 genes on fertility outcome. This meta-analysis evaluates whether women carrying BRCA mutations (BRCAm) have decreased ovarian reserve, in
Externí odkaz:
https://doaj.org/article/54d73027e7f04a6fbb8294f62e7eda69
Autor:
Marta Nerone, Lorenzo Rossi, Rosaria Condorelli, Vilma Ratti, Fabio Conforti, Antonella Palazzo, Rossella Graffeo
Publikováno v:
Cancers, Vol 15, Iss 13, p 3305 (2023)
We explored the outcomes of germline BRCA1/2 pathogenic/likely pathogenic variants (PVs/LPVs) in the endocrine-sensitive disease treated with first-line standard of care cyclin-dependent kinase 4/6 (CDK4/6) inhibitors. Three studies retrospectively s
Externí odkaz:
https://doaj.org/article/0c2eee751d5b43eb9d78bcef56ef06a5
Autor:
Fabio Conforti, Laura Pala, Eleonora Pagan, Elena Guerini Rocco, Vincenzo Bagnardi, Emilia Montagna, Giulia Peruzzotti, Tommaso De Pas, Caterina Fumagalli, Silvana Pileggi, Chiara Pesenti, Sergio Marchini, Giovanni Corso, Caterina Marchio’, Anna Sapino, Rossella Graffeo, Laetitia Collet, Philippe Aftimos, Christos Sotiriou, Martine Piccart, Richard D. Gelber, Giuseppe Viale, Marco Colleoni, Aron Goldhirsch
Publikováno v:
Breast, Vol 59, Iss , Pp 94-101 (2021)
Background: We report here for the first time, a comprehensive characterization of biological and clinical features of early-stage triple negative Invasive Lobular Carcinomas(TN-ILCs) Methods: We analyzed all consecutive patients with early-stage TN-
Externí odkaz:
https://doaj.org/article/0e41cdfb84f743128a8f6f2c40685bb2
Autor:
Matteo Lambertini, Marcello Ceppi, Anne-Sophie Hamy, Olivier Caron, Philip D. Poorvu, Estela Carrasco, Albert Grinshpun, Kevin Punie, Christine Rousset-Jablonski, Alberta Ferrari, Shani Paluch-Shimon, Angela Toss, Claire Senechal, Fabio Puglisi, Katarzyna Pogoda, Jose Alejandro Pérez-Fidalgo, Laura De Marchis, Riccardo Ponzone, Luca Livraghi, Maria Del Pilar Estevez-Diz, Cynthia Villarreal-Garza, Maria Vittoria Dieci, Florian Clatot, Francois P. Duhoux, Rossella Graffeo, Luis Teixeira, Octavi Córdoba, Amir Sonnenblick, Arlindo R. Ferreira, Ann H. Partridge, Antonio Di Meglio, Claire Saule, Fedro A. Peccatori, Marco Bruzzone, Marie Daphne t’Kint de Roodenbeke, Lieveke Ameye, Judith Balmaña, Lucia Del Mastro, Hatem A. Azim
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Young breast cancer (BC) patients carrying a germline BRCA pathogenic variant (mBRCA) have similar outcomes as non-carriers. However, the impact of the type of gene (BRCA1 vs. BRCA2) and hormone receptor status (positive [HR+] vs. negative [
Externí odkaz:
https://doaj.org/article/5b9aa2e66d9e4375afd2cb11e2219b70
Autor:
Fabio Conforti, Laura Pala, Eleonora Pagan, Giuseppe Viale, Vincenzo Bagnardi, Giulia Peruzzotti, Tommaso De Pas, Nadia Bianco, Rossella Graffeo, Elena Guerini Rocco, Andrea Vingiani, Richard D. Gelber, Alan S. Coates, Marco Colleoni, Aron Goldhirsch
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Invasive lobular carcinomas (ILCs) account for 10–15% of all breast cancers. They are characterized by an elevated endocrine responsiveness and by a long lasting risk of relapse over time. Here we report for the first time an an
Externí odkaz:
https://doaj.org/article/2afa7f973c6a4034a4efdbf7da29b151
Autor:
Susanna Stoll, Sheila Unger, Silvia Azzarello-Burri, Pierre Chappuis, Rossella Graffeo, Gabriella Pichert, Benno Röthlisberger, Francois Taban, Salome Riniker
Publikováno v:
Swiss Medical Weekly, Vol 151, Iss 3738 (2021)
This paper presents the Swiss guideline for genetic counselling and testing of individuals with an increased probability for carrying mutations in high risk cancer predisposition genes, particularly BRCA1 and BRCA2. It aims to help providers of genet
Externí odkaz:
https://doaj.org/article/08ff90e63fbe495a825e4ebbdb1a79c2
Autor:
Mahesh Sarki, Chang Ming, Monica Aceti, Günther Fink, Souria Aissaoui, Nicole Bürki, Rossella Graffeo, Karl Heinimann, Maria Caiata Zufferey, Christian Monnerat, Manuela Rabaglio, Ursina Zürrer-Härdi, Pierre O. Chappuis, Maria C. Katapodi, the CASCADE Consortium
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 10, p 1740 (2022)
Cascade genetic testing of relatives from families with pathogenic variants associated with hereditary breast and ovarian cancer (HBOC) or Lynch syndrome (LS) has important implications for cancer prevention. We compared the characteristics of relati
Externí odkaz:
https://doaj.org/article/ee32affd8078406ea5a38874f92fe6f1
Autor:
Carla Pedrazzani, Monica Aceti, Reka Schweighoffer, Andrea Kaiser-Grolimund, Nicole Bürki, Pierre O. Chappuis, Rossella Graffeo, Christian Monnerat, Olivia Pagani, Manuela Rabaglio, Maria C. Katapodi, Maria Caiata-Zufferey
Publikováno v:
Journal of Personalized Medicine, Vol 12, Iss 8, p 1249 (2022)
Low uptake of genetic services among members of families with hereditary breast and ovarian cancer (HBOC) suggests limitations of proband-mediated communication of genetic risk. This study explored how genetic information proceeds from healthcare pro
Externí odkaz:
https://doaj.org/article/e2e48d61bec642f1b84b30cfae79153f