MLX phosphorylation stabilizes the ChREBP-MLX heterotetramer on tandem E-boxes to control carbohydrate and lipid metabolism.

Autor: Cadena Del Castillo CE; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Deniz O; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., van Geest F; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Rosseels L; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Stockmans I; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium., Robciuc M; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Carpentier S; Facility for Systems Biology Based Mass Spectrometry, KU Leuven, Leuven, Belgium., Wölnerhanssen BK; St. Clara Research Ltd, St. Claraspital, Basel, Switzerland.; University of Basel, Basel, Switzerland., Meyer-Gerspach AC; St. Clara Research Ltd, St. Claraspital, Basel, Switzerland.; University of Basel, Basel, Switzerland., Peterli R; Clarunis, University Digestive Health Care Center, St. Clara Hospital and University Hospital Basel, Switzerland., Hietakangas V; Institute of Biotechnology, Helsinki Institute of Life Science, University of Helsinki, Helsinki, Finland., Shimobayashi M; Clinical and Experimental Endocrinology, Department of Chronic Diseases and Metabolism, KU Leuven, Leuven, Belgium.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 05. Date of Electronic Publication: 2024 Sep 05.