Zobrazeno 1 - 10 of 18 pro vyhledávání: '"Ross Zirkle"'
1
Akademický článek
Plant and algal lysophosphatidic acid acyltransferases increase docosahexaenoic acid accumulation at the sn-2 position of triacylglycerol in transgenic Arabidopsis seed oil.
Autor: Laura L Wayne, Daniel J Gachotte, Paul R Graupner, Yelena Adelfinskaya, David G McCaskill, James G Metz, Ross Zirkle, Terence A Walsh
Publikováno v: PLoS ONE, Vol 16, Iss 8, p e0256625 (2021)
Although docosahexaenoic acid (DHA), an important dietary omega-3 polyunsaturated fatty acid (PUFA), is at present primarily sourced from marine fish, bioengineered crops producing DHA may offer a more sustainable and cost-effective source. DHA has b
Externí odkaz: https://doaj.org/article/3caa47455514475396fed9df3c7764c5
Zobrazit plný text záznamu
2
Akademický článek
Vaccination against influenza with recombinant hemagglutinin expressed by Schizochytrium sp. confers protective immunity.
Autor: Anne-Cécile V Bayne, David Boltz, Carole Owen, Yelena Betz, Goncalo Maia, Parastoo Azadi, Stephanie Archer-Hartmann, Ross Zirkle, J Casey Lippmeier
Publikováno v: PLoS ONE, Vol 8, Iss 4, p e61790 (2013)
For the rapid production of influenza vaccine antigens in unlimited quantities, a transition from conventional egg-based production to cell-based and recombinant systems is required. The need for higher-yield, lower-cost, and faster production proces
Externí odkaz: https://doaj.org/article/b13dcbd2ca284daaab780763ff56a6a5
Zobrazit plný text záznamu
3
Plant and algal lysophosphatidic acid acyltransferases increase docosahexaenoic acid accumulation at the sn-2 position of triacylglycerol in transgenic Arabidopsis seed oil
Autor: Terence A. Walsh, James G. Metz, David McCaskill, Paul R. Graupner, Daniel J Gachotte, Yelena Adelfinskaya, Ross Zirkle, Laura L. Wayne
Publikováno v: PLoS ONE
PLoS ONE, Vol 16, Iss 8, p e0256625 (2021)
Although docosahexaenoic acid (DHA), an important dietary omega-3 polyunsaturated fatty acid (PUFA), is at present primarily sourced from marine fish, bioengineered crops producing DHA may offer a more sustainable and cost-effective source. DHA has b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43122a14d5cac86ff65d53d26a5c7160
https://pubmed.ncbi.nlm.nih.gov/34432852
Zobrazit plný text záznamu
5
Canola engineered with a microalgal polyketide synthase-like system produces oil enriched in docosahexaenoic acid
Autor: William Moskal, Patrick S Adu-Peasah, Scott Bevan, Stoltz Virginia, Pudota B. Bhaskar, Geny Anthony, Dayakar Pareddy, James G. Metz, Lauren Clark, Lyudmila Sidorenko, Ross Zirkle, Daniel J Gachotte, Pradeep Reddy Marri, Terence A. Walsh, Wei Chen, Cory M Larsen, P A Owens Merlo, Ronnie E Hampton, Steven Wensing
Publikováno v: Nature biotechnology. 34(8)
Dietary omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs), docosahexaenoic acid (DHA, C22:6) and eicosapentaenoic acid (EPA, C20:5) are usually derived from marine fish. Although production of both EPA and DHA has been engineered into land pl
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::242be0bad05815c3a327f0598d34f0c4
https://pubmed.ncbi.nlm.nih.gov/27398790
Zobrazit plný text záznamu
6
Biocatalytic Conversion of Avermectin to 4'-Oxo-Avermectin: Heterologous Expression of the ema1 Cytochrome P450 Monooxygenase
Autor: Frank Gross, Volker Jungmann, Thomas G. Buckel, James M. Ligon, Ross Zirkle, Pachlatko Johannes Paul, István Molnár, D. Steven Hill, Philip E. Hammer
Publikováno v: Molnár, I, Hill, D S, Zirkle, R, Hammer, P E, Gross, F, Buckel, T G, Jungmann, V, Pachlatko, J P & Ligon, J M 2005, ' Biocatalytic conversion of avermectin to 4″-oxo-avermectin : Heterologous expression of the ema1 cytochrome p450 monooxygenase ', Applied and Environmental Microbiology, vol. 71, no. 11, pp. 6977-6985 . https://doi.org/10.1128/AEM.71.11.6977-6985.2005
The cytochrome P450 monooxygenase Ema1 from Streptomyces tubercidicus R-922 and its homologs from closely related Streptomyces strains are able to catalyze the regioselective oxidation of avermectin into 4"-oxo-avermectin, a key intermediate in the m
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6ab1e3c0e6b11f3be2401eee2b722ff
https://doi.org/10.1128/aem.71.11.6977-6985.2005
Zobrazit plný text záznamu
7
Biocatalytic Conversion of Avermectin to 4'-Oxo-Avermectin: Characterization of Biocatalytically Active Bacterial Strains and of Cytochrome P450 Monooxygenase Enzymes and Their Genes
Autor: Philip E. Hammer, Thomas G. Buckel, James M. Ligon, Ross Zirkle, D. Steven Hill, J. Paul Pachlatko, Dagmar Buckel, István Molnár, Volker Jungmann
Publikováno v: Jungmann, V, Molnár, I, Hammer, P E, Hill, D S, Zirkle, R, Buckel, T G, Buckel, D, Ligon, J M & Pachlatko, J P 2005, ' Biocatalytic conversion of avermectin to 4″-oxo-avermectin : Characterization of biocatalytically active bacterial strains and of cytochrome p450 monooxygenase enzymes and their genes ', Applied and Environmental Microbiology, vol. 71, no. 11, pp. 6968-6976 . https://doi.org/10.1128/AEM.71.11.6968-6976.2005
4"-Oxo-avermectin is a key intermediate in the manufacture of the agriculturally important insecticide emamectin benzoate from the natural product avermectin. Seventeen biocatalytically active Streptomyces strains with the ability to oxidize avermect
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef3f44951e8085b028fd6b757065bfa
https://doi.org/10.1128/aem.71.11.6968-6976.2005
Zobrazit plný text záznamu
8
Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26
Autor: Thomas Schupp, Ross Zirkle, Steven Hill, James M. Ligon, James Joseph Beck, Jennifer Zawodny, István Molnár, Stephanie Money
Publikováno v: Ligon, J, Hill, S, Beck, J, Zirkle, R, Molnár, I, Zawodny, J, Money, S & Schupp, T 2002, ' Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26 ', Gene, vol. 285, no. 1-2, pp. 257-267 . https://doi.org/10.1016/S0378-1119(02)00396-7
A genomic DNA region of over 80 kb that contains the complete biosynthetic gene cluster for the synthesis of the antifungal polyketide metabolite soraphen A was cloned from Sorangium cellulosum So ce26. The nucleotide sequence of the soraphen A gene
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::828973a269c94b3d6fd48608fd93ffcc
https://doi.org/10.1016/S0378-1119(02)00396-7
Zobrazit plný text záznamu
9
Biochemical characterization of polyunsaturated fatty acid synthesis in Schizochytrium: release of the products as free fatty acids
Autor: James G. Metz, Jerry M. Kuner, James Casey Lippmeier, Bradley Rosenzweig, Ross Zirkle, Paul Gordon Roessler
Publikováno v: Plant physiology and biochemistry : PPB. 47(6)
In marine bacteria and some thraustochytrids (marine stramenopiles) long-chain polyunsaturated fatty acids (LC-PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are produced de novo by PUFA synthases. These large, multi-domain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5090e34b961211c8f5fbcefb75e4fa
https://pubmed.ncbi.nlm.nih.gov/19272783
Zobrazit plný text záznamu
10
The role of tandem acyl carrier protein domains in polyunsaturated fatty acid biosynthesis
Autor: James G Metz, Ross Zirkle, Lisa Braun, Steven G. Van Lanen, Hui Jiang, Leslie Richter, Ben Shen
Publikováno v: Journal of the American Chemical Society. 130(20)
Acyl carrier protein (ACP) plays an essential role in fatty acid and polyketide biosynthesis, and most of the fatty acid synthases (FASs) and polyketide synthases (PKSs) known to date are characterized with a single ACP for each cycle of chain elonga
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::152b59b8bcf1b2d7b65ae7addaa8144a
https://pubmed.ncbi.nlm.nih.gov/18444614
Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání

Omezení vyhledávání
Plný text Recenzováno Digitální knihovna AV ČR
Zdroje