Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ross Sibson"'
Autor:
Elisabeth J. Shaw, Brian Haylock, David Husband, Daniel du Plessis, D. Ross Sibson, Peter C. Warnke, Carol Walker
Publikováno v:
Analytical Cellular Pathology, Vol 33, Iss 2, Pp 81-94 (2010)
Background: Oligodendroglial tumors with 1p/19q loss are more likely to be chemosensitive and have longer survival than those with intact 1p/19q, but not all respond to chemotherapy, warranting investigation of the biological basis of chemosensitivit
Externí odkaz:
https://doaj.org/article/3956c6b428aa4d5796083b26cd4cde45
Autor:
Dong Liu Barraclough, Susan Sewart, Philip S. Rudland, Balvinder S. Shoker, D. Ross Sibson, Roger Barraclough, Michael P. A. Davies
Publikováno v:
Cellular Oncology, Vol 32, Iss 1-2, Pp 87-99 (2010)
Background: A major challenge of cancer research is to identify key molecules which are responsible for the development of the malignant metastatic phenotype, the major cause of cancer death.
Externí odkaz:
https://doaj.org/article/b0c6663e10d14ed89bb7f1a157e42114
Autor:
Daniel H. Palmer, John R. Arrand, Darren Barton, Wing Kin Syn, Nicholas D. James, Taha Elmetwali, Joseph J. Sacco, Puthen V. Jithesh, Richard M.D. Greensmith, D. Ross Sibson, Jawaher Ansari, Syed A. Hussain, Vijay Aachi, Bryony H. Lloyd
Publikováno v:
International Journal of Oncology
Despite advances in management, bladder cancer remains a major cause of cancer related complications. Characterisation of gene expression patterns in bladder cancer allows the identification of pathways involved in its pathogenesis, and may stimulate
Autor:
John P. Sloane, Balvinder S. Shoker, Michael P.A. Davies, Christine Jarvis, Mussawar Iqbal, D. Ross Sibson
Publikováno v:
The Journal of Pathology. 193:333-338
In normal breast, there is a negative association between expression of oestrogen receptor (ER) and the proliferation marker Ki67, indicating that ER-positive (ER+) cells do not divide, or that the receptor is down-regulated when they do so. However,
Autor:
Philip S. Rudland, Angela Platt-Higgins, Shanez Y. Anandappa, Roger Barraclough, Ross Sibson, John H. R. Winstanley
Publikováno v:
International Journal of Cancer. 88:209-216
A panel of human breast cancer specimens was examined for single base change mutations by DNA sequencing and for larger deletions using a PCR-based assay. In the cancer specimens examined, no sequencing variants were detected other than a previously
Publikováno v:
The Journal of Pathology. 188:237-244
As oestrogen is associated with most of the epidemiological risk factors for breast cancer, the number and distribution of oestrogen receptor positive (ER+) cells could have a bearing on the development of the disease. ER+ cells were thus studied in
Autor:
Christophe Polrier, Joachim Klose, Roger D. Cox, Dominique Simon, Sohaila Rastan, Ian J. Jackson, Peter W. Reed, Lisa Deakln, Catherine M. Abbott, Yvonne Boyd, Jonathan P. Stoye, Xavler Montagutelli, Philip Avner, Dillp Tailor, Jean-Louis Guénet, Franck Bourgade, Sarah Hodge, Ross Sibson, Bernard Macdonald, Maria Kelly, John A. Todd, Alison Pllz, Alan Ashworth, Hans Lehrach, Steve Miller, Maria Breen, Uma Gangadharan, Emma Tarttelln, Francis Rysavy, Leonard C. Schalkwyk, Martin Bishop, Linda McCarthy, Dominic P. Norris, David Shepherd, Steve Brown, Helen J. Blair, Gareth Ll. Maslen
Publikováno v:
Human Molecular Genetics. 3:621-627
982 progeny produced by a mouse Interspecific backcross between C57BL/6 and Mus spretus have been scored for at least 3 markers on each chromosome, completing an anchor map of 78 loci across the mouse genome. The anchor mapping identifies all the ava
Publikováno v:
BMC Cancer, Vol 7, Iss 1, p 131 (2007)
BMC CANCER
BMC Cancer
BMC CANCER
BMC Cancer
Background Oestrogen receptor beta (ERβ) modulates ERα activity; wild type ERβ (ERβ1) and its splice variants may therefore impact on hormone responsiveness of breast cancer. ERβ2/ERβcx acts as a dominant negative inhibitor of ERα and expressi
Publikováno v:
Cancer research. 65(9)
A suppression subtractive cDNA library representing mRNAs expressed at a higher level in the malignant human breast cancer cell line, MCF-7, relative to a benign breast tumor-derived cell line, Huma 123, contained a cDNA, M36, which was expressed in
Publikováno v:
Breast Cancer Research
Introduction Genetic abnormalities or mutations in premalignant breast lesions may have a role in progression toward malignancy or influence the behaviour of subsequent disease. The A908G (Lys303→Arg) change in the gene encoding oestrogen receptor-