Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ross P Walton"'
Autor:
Nicholas Glanville, Tamlyn J Peel, Armin Schröder, Julia Aniscenko, Ross P Walton, Susetta Finotto, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 12, Iss 9, p e1005913 (2016)
Current understanding of adaptive immune, particularly T cell, responses to human rhinoviruses (RV) is limited. Memory T cells are thought to be of a primarily T helper 1 type, but both T helper 1 and T helper 2 memory cells have been described, and
Externí odkaz:
https://doaj.org/article/41f08d0a69ea463e8d57dabe8a69beb5
Autor:
Jaideep Dhariwal, Jeremy Kitson, Reema E Jones, Grant Nicholson, Tanushree Tunstall, Ross P Walton, Grace Francombe, Jane Gilbert, Andrew J Tan, Robert Murdoch, Onn Min Kon, Peter J Openshaw, Trevor T Hansel
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0135363 (2015)
BackgroundPractical methods of monitoring innate immune mucosal responsiveness are lacking. Lipopolysaccharide (LPS) is a component of the cell wall of Gram negative bacteria and a potent activator of Toll-like receptor (TLR)-4. To measure LPS respon
Externí odkaz:
https://doaj.org/article/4fc555540a6c450c90cddbb2b287a8e8
Autor:
Stephanie Traub, Alexandra Nikonova, Alan Carruthers, Rebecca Dunmore, Katherine A Vousden, Leila Gogsadze, Weidong Hao, Qing Zhu, Katie Bernard, Jie Zhu, Michael Dymond, Gary R McLean, Ross P Walton, Nicholas Glanville, Alison Humbles, Musa Khaitov, Ted Wells, Roland Kolbeck, Andrew J Leishman, Matthew A Sleeman, Nathan W Bartlett, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 9, Iss 8, p e1003520 (2013)
Human rhinoviruses (HRV) cause the majority of common colds and acute exacerbations of asthma and chronic obstructive pulmonary disease (COPD). Effective therapies are urgently needed, but no licensed treatments or vaccines currently exist. Of the 10
Externí odkaz:
https://doaj.org/article/4f4766f10a70461e92a26bb6d95085f3
Autor:
Nicholas Glanville, Gary R McLean, Bruno Guy, Valerie Lecouturier, Catherine Berry, Yves Girerd, Christophe Gregoire, Ross P Walton, Rebecca M Pearson, Tatiana Kebadze, Nicolas Burdin, Nathan W Bartlett, Jeffrey W Almond, Sebastian L Johnston
Publikováno v:
PLoS Pathogens, Vol 9, Iss 9, p e1003669 (2013)
Human rhinovirus (RV) infections are the principle cause of common colds and precipitate asthma and COPD exacerbations. There is currently no RV vaccine, largely due to the existence of ∼150 strains. We aimed to define highly conserved areas of the
Externí odkaz:
https://doaj.org/article/07717b4341ab44fc8f7b80ae6c35376c
Autor:
Louise Slater, Nathan W Bartlett, Jennifer J Haas, Jie Zhu, Simon D Message, Ross P Walton, Annemarie Sykes, Samer Dahdaleh, Deborah L Clarke, Maria G Belvisi, Onn M Kon, Takashi Fujita, Peter K Jeffery, Sebastian L Johnston, Michael R Edwards
Publikováno v:
PLoS Pathogens, Vol 6, Iss 11, p e1001178 (2010)
The relative roles of the endosomal TLR3/7/8 versus the intracellular RNA helicases RIG-I and MDA5 in viral infection is much debated. We investigated the roles of each pattern recognition receptor in rhinovirus infection using primary bronchial epit
Externí odkaz:
https://doaj.org/article/7aaa3892a9194b66b016b415e301e757
Virus-induced Volatile Organic Compounds Are Detectable in Exhaled Breath during Pulmonary Infection
Autor:
Michael R. Edwards, Jadwiga A. Wedzicha, Andrea Romano, Ross P. Walton, Kirill Veselkov, Dexter J Wiseman, Ilaria Belluomo, Gavin C. Donaldson, Sebastian L. Johnston, Andrew I. Ritchie, Sacheen Kumar, Ivan Laponogov, George B. Hanna, Tasnim Shahridan Faiez, Aran Singanayagam, Faisal Kamal, Tatiana Kebadze, Maria-Belen Trujillo-Torralbo
Publikováno v:
Am J Respir Crit Care Med
Rationale: Chronic obstructive pulmonary disease (COPD) is a condition punctuated by acute exacerbations commonly triggered by viral and/or bacterial infection. Early identification of exacerbation triggers is important to guide appropriate therapy,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f63eba08ecfe1642a57b5f3c78c19c27
https://doi.org/10.1164/rccm.202103-0660oc
https://doi.org/10.1164/rccm.202103-0660oc
Type I conventional dendritic cells relate to disease severity in virus-induced asthma exacerbations
Autor:
Aoife, Cameron, Jaideep, Dhariwal, Nadine, Upton, Ismael, Ranz Jimenez, Malte, Paulsen, Ernie, Wong, Maria-Belen, Trujillo-Torralbo, Ajerico, Del Rosario, David J, Jackson, Michael R, Edwards, Sebastian L, Johnston, Ross P, Walton
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 52(4)
Rhinoviruses are the major precipitant of asthma exacerbations and individuals with asthma experience more severe/prolonged rhinovirus infections. Concurrent viral infection and allergen exposure synergistically increase exacerbation risk. Although d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbfdec3655be3ab150dd2afb4f6b5502
https://pubmed.ncbi.nlm.nih.gov/35212067
https://pubmed.ncbi.nlm.nih.gov/35212067
Autor:
David J. Cousins, Ernie Wong, Trevor T. Hansel, David A. Jackson, Ajerico del Rosario, Eteri Bakhsoliani, Jaideep Dhariwal, Malte Paulsen, Michael R. Edwards, Aoife Cameron, Ross P. Walton, Belen Trujillo-Torralbo, Sebastian L. Johnston
Rationale Type 2 innate lymphoid cells (ILC2s) are significant sources of type 2 cytokines, which are implicated in the pathogenesis of asthma and asthma exacerbations. The role of ILC2s in virus-induced asthma exacerbations is not well-characterized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::498121463a7b8682bb4b9fa01c689153
http://hdl.handle.net/10044/1/92512
http://hdl.handle.net/10044/1/92512
Autor:
Jaideep Dhariwal, Aoife Cameron, Ernie Wong, Malte Paulsen, Maria-Belen Trujillo-Torralbo, Ajerico del Rosario, Eteri Bakhsoliani, Tatiana Kebadze, Mark Almond, Hugo Farne, Leila Gogsadze, Julia Aniscenko, Batika M. J. Rana, Trevor T. Hansel, David J. Jackson, Onn Min Kon, Michael R. Edwards, Roberto Solari, David J. Cousins, Ross P. Walton, Sebastian L. Johnston, Paul Lavender, Hannah Gould, David Cousins, Antoon J. van Oosterhout, Nathan W. Bartlett, Patrick Mallia, Jerico del Rosario, Janet L. Smith, Matthew J. Edwards, Karen Affleck, Nil Turan Jurdzinski, Veronique Birault, Peter McErlean, Yu-Chang Wu, Nadine Upton, Ismael Ranz Jimenez
Publikováno v:
Am J Respir Crit Care Med
RATIONALE: Type 2 innate lymphoid cells (ILC2s) are significant sources of type 2 cytokines, which are implicated in the pathogenesis of asthma and asthma exacerbations. The role of ILC2s in virus-induced asthma exacerbations is not well characterize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816761f5244c7709ec80777271040f45
https://europepmc.org/articles/PMC8786078/
https://europepmc.org/articles/PMC8786078/
Autor:
Ross P. Walton, Adam Collison, Elizabeth Kepreotes, Ming Yang, Paul S. Foster, Nathan W. Bartlett, Matthew Morten, Michael R. Edwards, Leon A. Sokulsky, Ana Pereira de Siqueira, Thi Hiep Nguyen, Joerg Mattes, Sebastian L. Johnston
Publikováno v:
JCI Insight
JCI Insight, Vol 6, Iss 7 (2021)
JCI Insight, Vol 6, Iss 7 (2021)
Virus-induced respiratory tract infections are a major health burden in childhood, and available treatments are supportive rather than disease modifying. Rhinoviruses (RVs), the cause of approximately 80% of common colds, are detected in nearly half
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::047e6ce8873f842d2779e1546a1a1be0
http://hdl.handle.net/10044/1/92215
http://hdl.handle.net/10044/1/92215