Výsledky vyhledávání - "Ross N. Chapman"

Optimized Synthesis of Hydrogen-Bond Surrogate Helices: Surprising Effects of Microwave Heating on the Activity of Grubbs Catalysts

Autor: Ross N. Chapman, Paramjit S. Arora

Publikováno v: Organic Letters. 8:5825-5828

This manuscript discusses microwave-assisted solid-phase synthesis of hydrogen-bond surrogate based alpha-helices and analogues by ring-closing metathesis (RCM). Microwave-mediated RCM allows access to a greater variety of amino acid residues in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f743710ac6684095b36457bb00732c6
https://doi.org/10.1021/ol062443z

Zobrazit plný text záznamu

Multi-adduct derivatives of C60 for electron beam nano-resists

Autor: Mark Jennings, Koichiro Uekusa, Ross N. Chapman, Tetsuya Tada, Jacob Perkins, Irfan Hussain, Louise Eden, Marcus Phillips, Jon A. Preece, Wai Yee Cheung, E.J. Shelley, Takahiro Nakayama, Toshihiko Kanayama

Publikováno v: Microelectronic Engineering. :737-743

Methanofullerenes, C 60 derivatives, work as negative type electron beam resists, which have 10-nm scale resolution and high dry-etch durability. Their sensitivity (∼10 −3 C/cm 2 ) is one order of magnitude better than that of C 60 . We studied s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c10a9261a7dcaac18161b370346bfdf
https://doi.org/10.1016/s0167-9317(02)00541-5

Zobrazit plný text záznamu

Improved Sensitivity of Multi-adduct Derivatives of Fullerene

Autor: Irfan Hussain, Takahiro Nakayama, E.J. Shelley, Mark Jennings, Louise Eden, Ross N. Chapman, Koichiro Uekusa, Wai Yee Cheung, Marcus Phillips, Tetsuya Tada, Jacob Perkins, Jon A. Preece, Toshihiko Kanayama

Publikováno v: Journal of Photopolymer Science and Technology. 14:543-546

Methanofullerenes, a class of C60 derivatives, act as negative type e-beam resists with 10-nm resolution and high dry-etch durability. Their sensitivity is -10-3C/cm2, one order of magnitude better than that of C60. We studied sensitivities of methan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d5d93c2c46ea8acae94208acf28e417
https://doi.org/10.2494/photopolymer.14.543

Zobrazit plný text záznamu

Inhibition of Hypoxia Inducible Factor 1—Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix

Autor: Paramjit S. Arora, Bogdan Olenyuk, Swati Kushal, Ross N. Chapman, Laura K. Henchey, Ramin Dubey

Publikováno v: Journal of the American Chemical Society. 132:941-943

Designed ligands that inhibit hypoxia-inducible gene expression could offer new tools for genomic research and, potentially, drug discovery efforts for the treatment of neovascularization in cancers. We report a stabilized alpha-helix designed to tar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e941001551f9db20146376462a53a6a3
https://doi.org/10.1021/ja9082864

Zobrazit plný text záznamu

Trapping a folding intermediate of the alpha-helix: stabilization of the pi-helix

Autor: Ross N. Chapman, Anupam Patgiri, Paramjit S. Arora, Neville R. Kallenbach, Clay Bracken, John L. Kulp

Publikováno v: Biochemistry. 47(14)

We report the design, synthesis, and characterization of a short peptide trapped in a pi-helix configuration. This high-energy conformation was nucleated by a preorganized pi-turn, which was obtained by replacing an N-terminal intramolecular main cha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aa755ec6420377bbe3fda927fcdf555
https://pubmed.ncbi.nlm.nih.gov/18335996

Zobrazit plný text záznamu

Solid-phase synthesis of hydrogen-bond surrogate-derived alpha-helices

Autor: Ross N. Chapman, Gianluca Dimartino, Paramjit S. Arora, Deyun Wang

Publikováno v: Organic letters. 7(12)

[reaction: see text] This report describes the solid-phase synthesis of hydrogen-bond surrogate-derived artificial alpha-helices by a ring-closing metathesis reaction. From a series of metathesis catalysts evaluated for the synthesis of these helices

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846ff7abe87f07467c1dca5fbb7d4d36
https://pubmed.ncbi.nlm.nih.gov/15932205

Zobrazit plný text záznamu

A Highly Stable Short α-Helix Constrained by a Main-Chain Hydrogen-Bond Surrogate

Autor: Gianluca Dimartino, Paramjit S. Arora, Ross N. Chapman

Publikováno v: Journal of the American Chemical Society. 126:12252-12253

Herein we describe a strategy for the preparation of artificial alpha-helices involving replacement of one of the main-chain hydrogen bonds with a covalent linkage. To mimic the C=O...H-N hydrogen bond as closely as possible, we envisioned a covalent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8a1f3f391ba6224280cf79f9979dcd
https://doi.org/10.1021/ja0466659

Zobrazit plný text záznamu

Correction to Inhibition of Hypoxia Inducible Factor 1–Transcription Coactivator Interaction by a Hydrogen Bond Surrogate α-Helix

Autor: Bogdan Olenyuk, Ramin Dubey, Paramjit S. Arora, Laura K. Henchey, Swati Kushal, Ross N. Chapman

Publikováno v: Journal of the American Chemical Society. 134:8000-8000

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cfe915065116609007b372bf6e58c39
https://doi.org/10.1021/ja302676m

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání