Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ross Minter"'
Autor:
Rani K. Powers, Rachel Culp-Hill, Michael P. Ludwig, Keith P. Smith, Katherine A. Waugh, Ross Minter, Kathryn D. Tuttle, Hannah C. Lewis, Angela L. Rachubinski, Ross E. Granrath, María Carmona-Iragui, Rebecca B. Wilkerson, Darcy E. Kahn, Molishree Joshi, Alberto Lleó, Rafael Blesa, Juan Fortea, Angelo D’Alessandro, James C. Costello, Kelly D. Sullivan, Joaquin M. Espinosa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Down syndrome (DS) is caused by trisomy 21 (T21), but the underlying etiology of the related immune and neurological dysfunction is unclear. Here, the authors show that T21 activates the kynurenine pathway via increased interferon receptor copy numbe
Externí odkaz:
https://doaj.org/article/ab62f68b2f204b5a960385c4c5866d85
Autor:
Kathryn D. Tuttle, Katherine A. Waugh, Paula Araya, Ross Minter, David J. Orlicky, Michael Ludwig, Zdenek Andrysik, Matthew A. Burchill, Beth A.J. Tamburini, Colin Sempeck, Keith Smith, Ross Granrath, Dayna Tracy, Jessica Baxter, Joaquin M. Espinosa, Kelly D. Sullivan
Publikováno v:
Cell Reports, Vol 33, Iss 7, Pp 108407- (2020)
Summary: Individuals with Down syndrome (DS; trisomy 21) display hyperactivation of interferon (IFN) signaling and chronic inflammation, which could potentially be explained by the extra copy of four IFN receptor (IFNR) genes encoded on chromosome 21
Externí odkaz:
https://doaj.org/article/8fd7536ebdba4b9c98e33eeca1e00d4f
Autor:
Katherine A. Waugh, Paula Araya, Ahwan Pandey, Kimberly R. Jordan, Keith P. Smith, Ross E. Granrath, Santosh Khanal, Eric T. Butcher, Belinda Enriquez Estrada, Angela L. Rachubinski, Jennifer A. McWilliams, Ross Minter, Tiana Dimasi, Kelley L. Colvin, Dmitry Baturin, Andrew T. Pham, Matthew D. Galbraith, Kyle W. Bartsch, Michael E. Yeager, Christopher C. Porter, Kelly D. Sullivan, Elena W. Hsieh, Joaquin M. Espinosa
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1893-1908.e4 (2019)
Summary: People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions. However, the mech
Externí odkaz:
https://doaj.org/article/5e8ba4aab3a0402a9359cd3e3d5c2332
Autor:
Katherine A. Waugh, Ross Minter, Jessica Baxter, Congwu Chi, Kathryn D. Tuttle, Neetha P. Eduthan, Matthew D. Galbraith, Kohl T. Kinning, Zdenek Andrysik, Paula Araya, Hannah Dougherty, Lauren N. Dunn, Michael Ludwig, Kyndal A. Schade, Dayna Tracy, Keith P. Smith, Ross E. Granrath, Nicolas Busquet, Santosh Khanal, Ryan D. Anderson, Liza L. Cox, Belinda Enriquez Estrada, Angela L. Rachubinski, Hannah R. Lyford, Eleanor C. Britton, David J. Orlicky, Jennifer L. Matsuda, Kunhua Song, Timothy C. Cox, Kelly D. Sullivan, Joaquin M. Espinosa
Trisomy 21 causes Down syndrome, a condition characterized by cognitive impairments, immune dysregulation, and atypical morphogenesis. Using whole blood transcriptome analysis, we demonstrate that specific overexpression of four interferon receptors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0537897f7410b5176b3650f94e662bc
https://doi.org/10.1101/2022.02.03.478982
https://doi.org/10.1101/2022.02.03.478982
Autor:
Kelley L. Colvin, Kyle Bartsch, Ross Minter, Belinda Enriquez Estrada, Katherine A. Waugh, Tiana Dimasi, Angela L. Rachubinski, Ross E Granrath, Michael E. Yeager, Keith P Smith, Kelly D. Sullivan, Paula Araya, Jennifer A. McWilliams, Dmitry Baturin, Joaquín M. Espinosa, Matthew D. Galbraith, Kimberly R. Jordan, Santosh Khanal, Andrew T. Pham, Christopher C. Porter, Eric T. Butcher, Elena W Y Hsieh, Ahwan Pandey
Publikováno v:
Cell Reports, Vol 29, Iss 7, Pp 1893-1908.e4 (2019)
Summary: People with Down syndrome (DS; trisomy 21) display a different disease spectrum relative to the general population, including lower rates of solid malignancies and higher incidence of neurological and autoimmune conditions. However, the mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0952aa5471de759c757924c1f4f8fd8e
http://www.sciencedirect.com/science/article/pii/S221112471931352X
http://www.sciencedirect.com/science/article/pii/S221112471931352X
Publikováno v:
Current Zoology
Male cognition has gained recognition as an important potential player in sexual selection. A number of studies have found positive correlations between male sexual signals and cognitive performance and/or female preferences for males with better cog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fc3cce650c9f906bdc231abfb05262
https://doi.org/10.1093/cz/zoz014
https://doi.org/10.1093/cz/zoz014
Autor:
Paula Araya, Keith P Smith, Kelly D. Sullivan, Zdenek Andrysik, Beth A. Jirón Tamburini, Dayna Tracy, Katherine A. Waugh, Kathryn D. Tuttle, Ross E Granrath, Joaquín M. Espinosa, Colin Sempeck, Michael Ludwig, Ross Minter, Matthew A. Burchill, Jessica Baxter, David J. Orlicky
Publikováno v:
Cell Rep
Cell Reports
Cell Reports, Vol 33, Iss 7, Pp 108407-(2020)
Cell Reports
Cell Reports, Vol 33, Iss 7, Pp 108407-(2020)
Summary: Individuals with Down syndrome (DS; trisomy 21) display hyperactivation of interferon (IFN) signaling and chronic inflammation, which could potentially be explained by the extra copy of four IFN receptor (IFNR) genes encoded on chromosome 21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b465ca91e16c9edb88fde3c402ceee3
https://pubmed.ncbi.nlm.nih.gov/33207208
https://pubmed.ncbi.nlm.nih.gov/33207208
Autor:
Katherine A. Waugh, Paula Araya, Michael Ludwig, Joaquín M. Espinosa, David J. Orlicky, Kelly D. Sullivan, Kathryn D. Tuttle, Zdenek Andrysik, Ross Minter, Keith P Smith, Beth A. Jirón Tamburini, Colin Sempeck, Matthew A. Burchill
Cytokine storms are drivers of pathology and mortality in myriad viral infections affecting the human population. In SARS-CoV-2-infected patients, the strength of the cytokine storm has been associated with increased risk of acute respiratory distres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::119b48f08f20efc291a698cfa26f7758
https://doi.org/10.1101/2020.04.07.024455
https://doi.org/10.1101/2020.04.07.024455
Autor:
Katheleen Gardiner, Ross Minter
Publikováno v:
Genes, Vol 12, Iss 1697, p 1697 (2021)
Genes
Volume 12
Issue 11
Genes
Volume 12
Issue 11
Down syndrome (DS), trisomy of human chromosome 21 (Hsa21), is the most common genetic cause of intellectual disability. The Dp10(1)Yey (Dp10) is a mouse model of DS that is trisomic for orthologs of 25% of the Hsa21 protein-coding genes, the entiret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf8535b515b9ec8d68fedf511575c2a
https://doi.org/10.3390/genes12111697
https://doi.org/10.3390/genes12111697
Publikováno v:
Ecology and Evolution
Cognitive ability varies dramatically among individuals, yet the manner in which this variation correlates with reproduction has rarely been investigated. Here, we ask (1) do male sexual signals reflect their cognitive ability, and (2) is cognitive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86557f11c35cd04fa2ecaa51465364b0
https://doi.org/10.1002/ece3.3091
https://doi.org/10.1002/ece3.3091