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pro vyhledávání: '"Ross G. Clark"'
Autor:
Ross G. Clark
Publikováno v:
Language & History. 54:164-177
The career of P. A. Lanyon-Orgill (1924–2002) is outlined, providing an illustration of an institutional 'outsider', who, nevertheless, in the mid-twentieth century made his name quite well known among Pacific-area linguists, through a combination
Autor:
Ross G. Clark
Publikováno v:
Pediatric Nephrology. 20:290-294
Renal disease in children disrupts the growth hormone (GH) and insulin-like growth factor (IGF) axis and causes growth failure. Although GH therapy stimulates growth in these children, their short stature is likely due to a form of IGF-1 deficiency (
Autor:
Henry J. Waldvogel, Richard L.M. Faull, Rita Krishnamurthi, Peter D. Gluckman, Ross G. Clark, Jian Guan
Publikováno v:
Brain Research. 859:286-292
The effect of the N-terminal tripeptide of insulin-like growth factor (IGF)-1, glycine-proline-glutamate (GPE), as a neuroprotective agent for nigro-striatal dopaminergic neurons was examined in the present study using a rat model of Parkinson's dise
Publikováno v:
Circulation. 100:1734-1743
Background —Growth hormone (GH) improves cardiac function in the rat with myocardial infarction, but its effects in a model of primary dilated cardiomyopathy have not been reported. GH effects were examined at early (4 months) and late (10 months)
Autor:
Richard L.M. Faull, Tajrena Alexi, W.M.C. van Roon-Mom, Peter D. Gluckman, Chris E. Williams, Ross G. Clark, Paul E. Hughes
Publikováno v:
Experimental Neurology. 159:84-97
Huntington's disease is an incurable genetic neurological disorder characterized by the relatively selective degeneration of the striatum. Lesioning of the striatum in rodents using the excitatory amino acid agonist, quinolinic acid (QA), effectively
Autor:
M. Walton, Mike Dragunow, Chris E. Williams, Tajrena Alexi, Peter D. Gluckman, Ross G. Clark, Paul E. Hughes
Publikováno v:
Progress in Neurobiology. 57:421-450
This review primarily discusses work that has been performed in our laboratories and that of our direct collaborators and therefore does not represent an exhaustive review of the current literature. Our aim is to further discuss the role that gene ex
Publikováno v:
Endocrinology. 139:4120-4126
There has been considerable interest in using hormone replacement therapy to rejuvenate the involuted thymus during aging. GH and insulin-like growth factor-I (IGF-I), a mediator of GH actions, have been of particular interest because of their thymop
Autor:
Ross G. Clark, Kenneth R. Chien, Eric M. Sentianin, Nobuaki Tanaka, Lan Mao, Wesley Won, John Ross, Minoru Hongo, M. Dan McKirnan
Publikováno v:
Journal of Cardiac Failure. 4:213-224
Recombinant human growth hormone (rhGH) has shown beneficial effects on cardiac function after myocardial infarction (MI) in rats. High-dose angiotensin II (AT1) receptor blockade in normal rats inhibited the hypertrophic effect of growth hormone (GH
Autor:
John Ross, Tsutomu Ryoke, Howard A. Rockman, Lan Mao, Minoru Hongo, Nobuaki Tanaka, Ross G. Clark
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 275:H393-H399
Cardiac hypertrophic and contractile responses were studied in mice administered growth hormone (GH) and insulin-like growth factor (IGF-I) (8 mg ⋅ kg−1⋅ day−1), alone or in combination (IGF-I/GH), for 2 wk. Also, changes in expression of sel
Autor:
Lena M. S. Carlsson, Per-Arne Svensson, Ross G. Clark, Björn Carlsson, Thomas Jansson, Cesar Luiz Boguszewski
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:2878-2885
Several isoforms of human GH (hGH) are produced by two related genes expressed in the pituitary (hGH-N) and in the placenta (hGH-V). These genes consist of five exons (denoted 1-5) separated by four introns (denoted A-D). In the present report, two n