Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ross G Murphy"'
Autor:
Aideen McCabe, Gerard P. Quinn, Suneil Jain, Micheál Ó Dálaigh, Kellie Dean, Ross G. Murphy, Simon S. McDade
Publikováno v:
BMC Bioinformatics, Vol 25, Iss 1, Pp 1-13 (2024)
Abstract Background Advances in transcriptional profiling methods have enabled the discovery of molecular subtypes within and across traditional tissue-based cancer classifications. Such molecular subgroups hold potential for improving patient outcom
Externí odkaz:
https://doaj.org/article/6bf7d15909354ee88385117df5f155c1
Autor:
Ross G. Murphy, Alan Gilmore, Seedevi Senevirathne, Paul G. O'Reilly, Melissa LaBonte Wilson, Suneil Jain, Darragh G. McArt
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 20, Iss , Pp 5547-5563 (2022)
The development of gene signatures is key for delivering personalized medicine, despite only a few signatures being available for use in the clinic for cancer patients. Gene signature discovery tends to revolve around identifying a single signature.
Externí odkaz:
https://doaj.org/article/66ec88fd3fe64bc78e4b998506b28700
Autor:
Joe M. O'Sullivan, Suneil Jain, David Waugh, Aideen C. Roddy, Ross G Murphy, Melissa J. LaBonte, Shambhavi Srivastava, Darragh G. McArt, Esther Baena
Publikováno v:
Nar Genomics and Bioinformatics
Murphy, R, McArt, D, O'Sullivan, J, Waugh, D, Srivastava, S K, Roddy, A, Baena, E, Jain, S & LaBonte Wilson, M 2020, ' Prostate cancer heterogeneity assessment with multi-regional sampling and alignment-free methods ', NAR Genomics and Bioinformatics, vol. 2, no. 3, lqaa062 . https://doi.org/10.1093/nargab/lqaa062
Murphy, R, McArt, D, O'Sullivan, J, Waugh, D, Srivastava, S K, Roddy, A, Baena, E, Jain, S & LaBonte Wilson, M 2020, ' Prostate cancer heterogeneity assessment with multi-regional sampling and alignment-free methods ', NAR Genomics and Bioinformatics, vol. 2, no. 3, lqaa062 . https://doi.org/10.1093/nargab/lqaa062
Combining alignment-free methods for phylogenetic analysis with multi-regional sampling using next-generation sequencing can provide an assessment of intra-patient tumour heterogeneity. From multi-regional sampling divergent branching, we validated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f18218a2e260284f886fb58d8386c0c
http://europepmc.org/articles/PMC7440682
http://europepmc.org/articles/PMC7440682
Autor:
Paul C. Boutros, Lara Dura-Perez, Ross G Murphy, Jessica Ray, Michelle R. Downes, Jouhyun Jeon, Christianne Hoey, Suneil Jain, Nuala McCabe, Ian G. Mills, Charles M. Haughey, Stanley K. Liu
Publikováno v:
Ray, J, Haughey, C, Hoey, C, Jeon, J, Murphy, R, Dura-Perez, L, McCabe, N, Downes, M, Jain, S, Boutros, P C, Mills, I G & Liu, S K 2019, ' miR-191 promotes radiation resistance of prostate cancer through interaction with RXRA ', Cancer Letters . https://doi.org/10.1016/j.canlet.2019.12.025
Radiation therapy is a common treatment for prostate cancer, however recurrence remains a problem. MicroRNA expression is altered in prostate cancer and may promote therapy resistance. Through bioinformatic analyses of TCGA and CPC-GENE patient cohor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::985694b4fb2b3cd803afd4edd84db309
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