Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ross F. Lawrence"'
Publikováno v:
Journal of Chromatography B: Biomedical Sciences and Applications. 732:287-298
An assay method for the quantification of cyclophosphamide (CY) and five metabolites from human plasma is presented. The procedure is adapted to the chemical properties of the compounds of interest: non-polar compounds are extracted into methylene ch
Autor:
Rheem A. Totah, Martha J. Somerman, Lei Li, Hai Zhang, Brianne S. Raccor, Ross F. Lawrence, Jianxun Sun
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 935
An in vitro method for extraction and quantification of zoledronic acid (ZA) from murine bone was developed. Whole mouse bones were incubated in ZA solutions with predetermined concentrations and bound ZA was subsequently extracted from bone with pho
Publikováno v:
Journal of chromatography. B, Biomedical sciences and applications. 741(2)
This report describes an assay for the H1-receptor antagonist, terfenadine, and its two primary metabolites, terfenadine alcohol (TOH) and azacyclonol (AZ), using positive-ion, electrospray ionization–liquid chromatography–mass spectrometry. The
Autor:
Ross F. Lawrence, William N. Howald, Kenneth A. Walsh, J. Alex Taylor, Lowell H. Ericsson, Kheng B. Lim, Houle Wang, Murray Hackett
Publikováno v:
Analytical biochemistry. 250(2)
Electrospray ionization sources, used with triple quadrupole mass spectrometers from PE/Sciex (API III+), Micromass (Quattro II), and Finnigan (TSQ 7000), were modified with a 35-gauge stainless steel needle. The dimensions of the needle were 63 micr
Publikováno v:
Journal of chromatography. B, Biomedical applications. 661(2)
An electron-capture negative-ion chemical ionization gas chromatographic—mass spectrometric assay for mefloquine, an antimalarial drug used in the treatment of drug-resistant Plasmodium falciparum malaria, is described. The method, developed in sup
Publikováno v:
Journal of Heterocyclic Chemistry. 21:1293-1296
1-Phenylnaphthalene undergoes sulfur bridging at 500° in the presence of hydrogen sulfide and a heterogeneous catalyst to produce benzo[b]naphtho[1,2-d]thiophene (13%). 3-Methylphenanthrene and 9-formylphenanthrene diethyl acetal (7b) give sulfur br
Publikováno v:
Journal of Heterocyclic Chemistry. 15:417-420
Phenanthro[4,5-bcd]thiophene (1) is converted into phenanthrene (2) (50%) and a mixture of methylphenanthrenes (3) (12%) by means of methanol and a sulfided cobaltous oxide-molybdic oxide-aluminum oxide catalyst (CMA-1) at 450° in a flow system. Sim
Autor:
Stanley Raucher, Ross F. Lawrence
Publikováno v:
Tetrahedron. 39:3731-3735
5-Oxo-Na-tosyl-14,21-dehydrosecodine (8) was prepared by bromination of 6 followed by double dehydrobromination with ethyl aluminum dichloride in HMPA. When a dilute solution of 8 was heated, 10 was formed via intramolecular hydride transfer and cycl
Publikováno v:
Journal of Heterocyclic Chemistry. 16:73-79
Thin layer chromatographic Rf data on silica gel are reported for 64 compounds containing either a thiole sulfur atom, one or more azine nitrogen atoms, or both. Thiole adsorbates are compared with 28 aromatic hydrocarbons and non-heterocyclic sulfur
Publikováno v:
Tetrahedron Letters. 21:4335-4338
Trimethyl β-(methoxy)orthopropionate, a compound which is thermally stable at 190 °C for prolonged times, may be utilized as a synthon for the preparation of methyl α-substituted acrylates via Claisen ortho ester rearrangement with allylic alcohol