Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ross E. Crabtree"'
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 40:830-833
Lergotrile (Compound 83636), a specific inhibitor of prolactin release, was administered to 5 women with galactorrhea. Only 1 of the 5 had an elevated serum prolactin (hPRL) value, but Compound 83636 induced a decrease in serum hPRL in all cases. All
Autor:
Rodda Be, Warrick P, Alan Rubin, Robert L. Wolen, L. Helleberg, Ross E. Crabtree, Gruber Cm, Anthony S. Ridolfo, Chernish Sm
Publikováno v:
Current Medical Research and Opinion. 2:529-544
Pharmacodynamic studies have shown that fenoprofen is readily absorbed from the gastro-intestinal tract following oral administration and that the disposition of absorbed fenoprofen does not differ...
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 39:579-584
Compound 83636 (lergotrile), an ergoline derivative, inhibits prolactin release in vitro and in vivo in animals. Studies were designed to evaluate its clinical pharmacologic effects in man. Its chronic administration (2 mg 3 times daily) to normal vo
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 47:602-605
Labeled compounds were used to study the metabolism of salicylates in rats. A method, electrophoretic separation, was developed to identify the oxidative metabolites. Analysis of tissue extracts by this method generally revealed only the administered
Publikováno v:
Clinical Pharmacology & Therapeutics. 14:987-991
Publikováno v:
Journal of the American Pharmaceutical Association (Scientific ed.). 45:667-669
Salicylates act as antipyretics only on elevated body temperatures. In searching for the mechanism of this action, the blood salicylate levels have been investigated after the administration of an antipyretic dose of aspirin to fevered and nonfevered
Publikováno v:
Science. 177:62-64
11-Hydroxy-Delta(9)-tetrahydrocannabinol, administered intravenously to man, produces psychologic and pharmacologic effects that persist for several hours. The drug and its metabolites are excreted in urine and feces for more than 1 week. The pharmac
Publikováno v:
Life sciences. 16(8)
δ 9 -THC, 11-OH-δ 9 -THC or placebo was administered to casual marihuana smokers in a double-blind, crossover study. δ 9 -THC and 11-OH-δ 9 -THC produced marked pharmacologic and psychologic effects (tachycardia, increased symptom score and psych
Publikováno v:
Controlled clinical trials. 5
Tracer microspheres are small, ceramic-like particles (50 μm) containing one of several radionuclide markers. We have utilized them over a period of 9 years as quantitative fecal markers for recovery measurements in metabolic studies. The markers ha