Zobrazeno 1 - 10
of 109
pro vyhledávání: '"Ross D. Brown"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 1, Pp 25-32 (2016)
The confinement of multiple myeloma (MM) to the bone marrow microenvironment requires an invasive bone marrow biopsy to monitor the malignant compartment. The existing clinical tools used to determine treatment response and tumor relapse are limited
Externí odkaz:
https://doaj.org/article/3d61214c6dde4504b2b92224cbc437d5
Autor:
Bradley Augustson, Simon J. Harrison, Andrew W. Roberts, Andrew C.W. Zannettino, Anna Kalff, Hang Quach, Jeff Szer, Noemi Horvath, Dipti Talaulikar, Akash Kalro, Andrew Spencer, Anna Johnston, Wilfrid J Jaksic, Doug Joshua, H. Miles Prince, Joy Ho, Oi Lin Lee, Cindy Lee, Silvia Ling, Chris Ward, John Gibson, Ross D. Brown, Peter Mollee
Publikováno v:
Internal Medicine Journal. 47:938-951
Multiple myeloma (MM) is a haematological malignancy characterised by the clonal proliferation of plasma cells in the bone marrow. More than 80% of patients with MM display evidence of myeloma bone disease (MBD), characterised by the formation of ost
Publikováno v:
International Journal of Oncology. 49:33-50
Multiple myeloma (MM) is a mature B cell neoplasm that results in multi-organ failure. The median age of onset, diverse clinical manifestations, heterogeneous survival rate, clonal evolution, intrinsic and acquired drug resistance have impact on the
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 18, Iss 1, Pp 25-32 (2016)
The confinement of multiple myeloma (MM) to the bone marrow microenvironment requires an invasive bone marrow biopsy to monitor the malignant compartment. The existing clinical tools used to determine treatment response and tumor relapse are limited
Autor:
Bradley Augustson, L. Catley, Joy Ho, Douglas E. Joshua, Andrew Spencer, Noemi Horvath, Wilfrid J Jaksic, Andrew C.W. Zannettino, Ross D. Brown, Peter Mollee, Henry Miles Prince, John Gibson, Bik To, Jeff Szer, Simon J. Harrison, Hang Quach, Dipti Talaulikar, Andrew W. Roberts
Publikováno v:
Internal Medicine Journal. 45:335-343
Options for treatment of elderly patients with multiple myeloma have expanded substantially following the development of immunomodulatory drugs (IMiD), proteasome inhibitors and with enhancement in safety of high-dose therapy and autologous stem cell
Autor:
Andrew Spencer, Douglas E. Joshua, Daniel Daniher, Ross D. Brown, John Gibson, Melinda Jeffels, P. Joy Ho
Publikováno v:
Leukemia & Lymphoma. 53:1728-1734
The translocation t(4;14) is associated with a poor prognosis in myeloma, but its effect in the setting of new drugs such as thalidomide, bortezomib and lenalidomide continues to be investigated, and the role of candidate genes such as FGFR3 (fibrobl
Autor:
Jia Li, Yuling Chen, Karieshma Kabani, Tetsuo Yamagishi, Warren Kaplan, Daniel Man-Yuen Sze, Ross D. Brown, Suilin Mo, Mark J. Cowley, Yen Siew Loh, P. Joy Ho, Shihong Yang, Douglas E. Joshua, Esther Aklilu
Publikováno v:
Blood. 115:3580-3588
T cells contribute to host-tumor interactions in patients with monoclonal gammopathies. Expansions of CD8+CD57+ T-cell receptor Vβ–positive (TCRVβ+)–restricted cytotoxic T-cell (CTL) clones are found in 48% of patients with multiple myeloma and
Publikováno v:
Scandinavian Journal of Haematology. 30:110-116
Granulocyte-monocyte colony forming cell (GM-CFC) concentration and the proportion of GM-CFC in DNA synthesis (S) were determined in 43 patients with varying degrees of selective neutropenia, including 5 patients who were normal extremes (2.0–2.5 t
Publikováno v:
Scandinavian Journal of Haematology. 22:121-128
Bone marrow colony forming cell (CFC) concentration and the proportion of CFC in DNA synthesis were studied in myeloproliferative disorders and aplastic anaemia. Growth patterns of bone marrow cells in agar cultures were able to supplement traditiona