Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ross C. Wilson"'
Publikováno v:
Archaea, Vol 2011 (2011)
RNase P is a highly conserved ribonucleoprotein enzyme that represents a model complex for understanding macromolecular RNA-protein interactions. Archaeal RNase P consists of one RNA and up to five proteins (Pop5, RPP30, RPP21, RPP29, and RPP38/L7Ae)
Externí odkaz:
https://doaj.org/article/85e3a261cd03472f846677668bf6724e
Autor:
Dana V. Foss, Joseph J. Muldoon, David N. Nguyen, Daniel Carr, Srishti U. Sahu, John M. Hunsinger, Stacia K. Wyman, Netravathi Krishnappa, Rima Mendonsa, Elaine V. Schanzer, Brian R. Shy, Vivasvan S. Vykunta, Vincent Allain, Zhongmei Li, Alexander Marson, Justin Eyquem, Ross C. Wilson
Publikováno v:
Nature biomedical engineering, vol 7, iss 5
CRISPR-mediated genome editing of primary human lymphocytes is typically carried out via electroporation, which can be cytotoxic, cumbersome and costly. Here we show that the yields of edited primary human lymphocytes can be increased substantially b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d98d71ebdbd567262a88ba896fa4ca
https://escholarship.org/uc/item/0d8552gt
https://escholarship.org/uc/item/0d8552gt
Autor:
Ross C. Wilson
Publikováno v:
GEN Biotechnology. 1:30-32
Autor:
Ross C. Wilson, Kevin D. Wells, W. Mark Saltzman, Philip J. Santangelo, Guohua Yi, Aravind Asokan, Shengdar Q. Tsai, Nenad Bursac, R. Holland Cheng, Shaoqin Gong, Gang Bao, Jennifer A. Doudna, Venkata S. Sabbisetti, Jarryd M. Campbell, Ryuji Morizane, Charles A. Gersbach, Mary E. Dickinson, Jon D. Hennebold, Kit S. Lam, Zheng-Yi Chen, John T. Hinson, Melinda R. Dwinell, Daniel G. Anderson, William R. Lagor, Qiaobing Xu, Melissa C. Skala, Jennifer A. Lewis, David J. Segal, Samantha Maragh, Guoping Feng, Stephen C. Ekker, Benjamin E. Deverman, Jonathan K. Watts, Alice F. Tarantal, Moriel H. Vandsburger, George A. Truskey, Ionita Ghiran, Marina E. Emborg, Jeff W.M. Bulte, Scot A. Wolfe, James E. Dahlman, Niren Murthy, Paul B. McCray, Erik J. Sontheimer, John C. Tilton, David T. Curiel, Benjamin S. Freedman, Guangping Gao, Mary Shimoyama, Kam W. Leong, Jiangbing Zhou, P. J. Brooks, Samira Kiani, Krystof S. Bankiewicz, Karl J. Clark, Jillian F. Banfield, Jon E. Levine, Krishanu Saha, Todd C. McDevitt, David R. Liu, Randall S. Prather, Daniel F. Carlson, Peter M. Glazer, Elliot L. Chaikof, Jason D. Heaney, Subhojit Roy, John A. Ronald, Stephen A. Murray, Cathleen M. Lutz, Anastasia Khvorova, Wen Xue, Sushmita Roy, Oleg Mirochnitchenko, Danith H. Ly, David M. Gamm
Publikováno v:
Nature
The move from reading to writing the human genome offers new opportunities to improve human health. The United States National Institutes of Health (NIH) Somatic Cell Genome Editing (SCGE) Consortium aims to accelerate the development of safer and mo
Autor:
Gabriel Neiman, Lee W. Riley, Hesong Han, Niren Murthy, Yumiao Zhang, Clarissa A. Borges, Ross C. Wilson, Piotr Hadaczek, Jie Li, Maomao He, Rima Mendonsa, Krystof S. Bankiewicz, Kevin E. Healy, Joachim Justad Røise, Victoria R Holm, Corinne M. Sadlowski
Publikováno v:
Chemical Science
Reduction sensitive linkers (RSLs) have the potential to transform the field of drug delivery due to their ease of use and selective cleavage in intracellular environments. However, despite their compelling attributes, developing reduction sensitive
Autor:
Dana Carroll, Ross C. Wilson
Publikováno v:
The CRISPR Journal. 2:280-284
There is no shortage of enthusiasm for the clinical potential of CRISPR-based genome editing: many life-changing cures appear to be just around the corner. However, as mature genetic therapies reach the market, it seems that million-dollar price tags
Publikováno v:
Transfusion. 59:1389-1399
Clustered regularly interspaced short palindromic repeats (CRISPR)-driven genome editing has rapidly transformed preclinical biomedical research by eliminating the underlying genetic basis of many diseases in model systems and facilitating the study
Autor:
Ariana Hirsh, Robert Dullea, Meihua Tu, Spiros Liras, Joan Compte Barrón, Kris A. Borzilleri, Nannan Ma, Rima Mendonsa, Justin Bellenger, Romain Rouet, Lorena de Oñate, Xidong Feng, Jennifer A. Doudna, Nathanael G. Lintner, David M. Rubitski, Benjamin A. Thuma, Marc D. Roy, Alison H. Varghese, Kim F. McClure, Ross C. Wilson, Thomas J. McLellan, Hanna M. Wisniewska, James E. Finley, Boris A. Chrunyk, Vincent Mascitti, Kaihong Zhou, Kevin D. Hesp
Publikováno v:
Journal of the American Chemical Society, vol 140, iss 21
Rouet, Romain; Thuma, Benjamin A; Roy, Marc D; Lintner, Nathanael G; Rubitski, David M; Finley, James E; et al.(2018). Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.. Journal of the American Chemical Society, 140(21), 6596-6603. doi: 10.1021/jacs.8b01551. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/61k3t664
Rouet, Romain; Thuma, Benjamin A; Roy, Marc D; Lintner, Nathanael G; Rubitski, David M; Finley, James E; et al.(2018). Receptor-Mediated Delivery of CRISPR-Cas9 Endonuclease for Cell-Type-Specific Gene Editing.. Journal of the American Chemical Society, 140(21), 6596-6603. doi: 10.1021/jacs.8b01551. UC Berkeley: Retrieved from: http://www.escholarship.org/uc/item/61k3t664
CRISPR-Cas RNA-guided endonucleases hold great promise for disrupting or correcting genomic sequences through site-specific DNA cleavage and repair. However, the lack of methods for cell- and tissue-selective delivery currently limits both research a
Autor:
Ross C. Wilson, Dana V. Foss
Publikováno v:
Trends in Molecular Medicine. 24:822-824
Despite the unparalleled therapeutic promise of genome editing, its curative power is currently limited by the substantial difficulty in delivering DNA-cutting enzymes to the cells in need of correction. A recent study demonstrates the potential for
Publikováno v:
The CRISPR journal. 1(6)
The use of CRISPR-derived, RNA-guided nucleases for genome editing has shown great promise for addressing genetic disease. Encouraging work in cell culture and animal models has demonstrated the capability of genome-editing enzymes to correct disease