Zobrazeno 1 - 10
of 315
pro vyhledávání: '"Ross C Hardison"'
Autor:
Cheryl A Keller, Alexander Q Wixom, Elisabeth F Heuston, Belinda Giardine, Chris C -S Hsiung, Maria R Long, Amber Miller, Stacie M Anderson, April Cockburn, Gerd A Blobel, David M Bodine, Ross C Hardison
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 6 (2021)
AbstractChromatin immunoprecipitation followed by massively parallel, high throughput sequencing (ChIP-seq) is the method of choice for genome-wide identification of DNA segments bound by specific transcription factors or in chromatin with particular
Externí odkaz:
https://doaj.org/article/187ad77994884baf9b47056148b28010
Autor:
Rena Zheng, Boris Rebolledo-Jaramillo, Yiwei Zong, Liqing Wang, Pierre Russo, Wayne Hancock, Ben Z Stanger, Ross C Hardison, Gerd A Blobel
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83723 (2013)
GATA transcription factors and their Friend of Gata (FOG) cofactors control the development of diverse tissues. GATA4 and GATA6 are essential for the expansion of the embryonic liver bud, but their expression patterns and functions in the adult liver
Externí odkaz:
https://doaj.org/article/cc1b818cb1d9408b9cafd0956bb7a359
Autor:
Ross C Hardison
Publikováno v:
PLoS Biology, Vol 1, Iss 2, p E58 (2003)
Externí odkaz:
https://doaj.org/article/3e8d184be3b24446b43cdcb9d1d24677
Autor:
Guanjue Xiang, Belinda Giardine, Lin An, Chen Sun, Cheryl A. Keller, Elisabeth F. Heuston, Stacie M. Anderson, Martha Kirby, David Bodine, Yu Zhang, Ross C. Hardison
Publikováno v:
BMC Bioinformatics, Vol 24, Iss 1, Pp 1-19 (2023)
Abstract Background Epigenetic modification of chromatin plays a pivotal role in regulating gene expression during cell differentiation. The scale and complexity of epigenetic data pose significant challenges for biologists to identify the regulatory
Externí odkaz:
https://doaj.org/article/5ffe37119b794e6e9a7d5b9bec15d47b
Autor:
Jie Xu, Fan Song, Huijue Lyu, Mikoto Kobayashi, Baozhen Zhang, Ziyu Zhao, Ye Hou, Xiaotao Wang, Yu Luan, Bei Jia, Lena Stasiak, Josiah Hiu-yuen Wong, Qixuan Wang, Qi Jin, Qiushi Jin, Yihao Fu, Hongbo Yang, Ross C. Hardison, Sinisa Dovat, Leonidas C. Platanias, Yarui Diao, Yue Yang, Tomoko Yamada, Aaron D. Viny, Ross L. Levine, David Claxton, James. R. Broach, Hong Zheng, Feng Yue
Publikováno v:
Nature
Acute myeloid leukaemia (AML) represents a set of heterogeneous myeloid malignancies, and hallmarks include mutations in epigenetic modifiers, transcription factors and kinasessup1-5/sup. The extent to which mutations in AML drive alterations in chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5efe6c55af9f1fad54c782b47b0626
https://doi.org/10.1038/s41586-022-05365-x
https://doi.org/10.1038/s41586-022-05365-x
Autor:
Guanjue Xiang, Xi He, Belinda M. Giardine, Kathryn J. Weaver, Dylan J. Taylor, Rajiv C. McCoy, Camden Jansen, Cheryl A. Keller, Alexander Q. Wixom, April Cockburn, Amber Miller, Qian Qi, Yanghua He, Yichao Li, Jens Lichtenberg, Elisabeth F. Heuston, Stacie M. Anderson, Jing Luan, Marit W. Vermunt, Feng Yue, Michael E.G. Sauria, Michael C. Schatz, James Taylor, Berthold Göttgens, Jim R. Hughes, Douglas R. Higgs, Mitchell J. Weiss, Yong Cheng, Gerd A. Blobel, David Bodine, Yu Zhang, Qunhua Li, Shaun Mahony, Ross C. Hardison
Knowledge of locations and activities ofcis-regulatory elements (CREs) is needed to decipher basic mechanisms of gene regulation and to understand the impact of genetic variants on complex traits. Previous studies identified candidate CREs (cCREs) us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef37c806f6c18c3930749db34dc396f5
https://doi.org/10.1101/2023.04.02.535219
https://doi.org/10.1101/2023.04.02.535219
Autor:
Kunhua Qin, Xianjiang Lan, Peng Huang, Megan S. Saari, Eugene Khandros, Cheryl A Keller, Belinda M. Giardine, Osheiza Abdulmalik, Junwei Shi, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Blood.
The fetal (HbF)-to-adult (HbA) hemoglobin switch is a paradigm for developmental gene expression control with relevance to sickle cell disease and b-thalassemia. Polycomb repressive complex (PRC) proteins regulate this switch, and an inhibitor of PRC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2836ffab659abb0f4353fd99a0d730d4
https://doi.org/10.1182/blood.2022019578
https://doi.org/10.1182/blood.2022019578
Autor:
Kunhua Qin, Peng Huang, Ruopeng Feng, Cheryl A. Keller, Scott A. Peslak, Eugene Khandros, Megan S. Saari, Xianjiang Lan, Thiyagaraj Mayuranathan, Phillip A. Doerfler, Osheiza Abdulmalik, Belinda Giardine, Stella T. Chou, Junwei Shi, Ross C. Hardison, Mitchell J. Weiss, Gerd A. Blobel
Publikováno v:
Nature Genetics. 54:874-884
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d01ccfde1bb041df2c3ef2817959b04a
https://doi.org/10.1038/s41588-022-01076-1
https://doi.org/10.1038/s41588-022-01076-1
Autor:
Jing Luan, Marit W. Vermunt, Camille M. Syrett, Allison Coté, Jacob M. Tome, Haoyue Zhang, Anran Huang, Jennifer M. Luppino, Cheryl A. Keller, Belinda M. Giardine, Shiping Zhang, Margaret C. Dunagin, Zhe Zhang, Eric F. Joyce, John T. Lis, Arjun Raj, Ross C. Hardison, Gerd A. Blobel
Publikováno v:
Nat Struct Mol Biol
Transcription at most promoters is divergent, initiating at closely spaced oppositely oriented core promoters to produce sense transcripts along with often unstable upstream antisense transcripts (uasTrx). How antisense transcription is regulated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875560af4f05b41231d06865134f4090
https://europepmc.org/articles/PMC10015438/
https://europepmc.org/articles/PMC10015438/
Autor:
Yi Qiu, Jiwang Zhang, Bowen Yan, Jennifer Yang, Minyoung Kim, Nicholas Cesari, John Strouboulis, Huacheng Luo, Ross C. Hardison, Suming Huang, Tao Yang
Publikováno v:
Nucleic Acids Research
The activity of hematopoietic factor GATA-1 is modulated through p300/CBP-mediated acetylation and FOG-1 mediated indirect interaction with HDAC1/2 containing NuRD complex. Although GATA-1 acetylation is implicated in GATA-1 activation, the role of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5342f261b241aa41d02b8cbbdb8d55
https://doi.org/10.1093/nar/gkab737
https://doi.org/10.1093/nar/gkab737