Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Ross B, Fulton"'
Autor:
Anissa S. H. Chan, Takashi O. Kangas, Xiaohong Qiu, Mark T. Uhlik, Ross B. Fulton, Nadine R. Ottoson, Keith B. Gorden, Yumi Yokoyama, Michael E. Danielson, Trinda M. Jevne, Kyle S. Michel, Jeremy R. Graff, Nandita Bose
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Imprime PGG (Imprime) is in late-stage clinical development as a combinatorial agent with several therapeutic modalities. Here we present pre-clinical mechanistic data supportive of Imprime, a soluble yeast β-1,3/1,6-glucan pathogen-associated molec
Externí odkaz:
https://doaj.org/article/3ecab3a75dcc4fa29265f88741647ad9
Autor:
Emily N Truckenbrod, Kristina S Burrack, Todd P Knutson, Henrique Borges da Silva, Katharine E Block, Stephen D O'Flanagan, Katie R Stagliano, Arthur A Hurwitz, Ross B Fulton, Kristin R Renkema, Stephen C Jameson
Publikováno v:
eLife, Vol 10 (2021)
Self-specific CD8+T cells can escape clonal deletion, but the properties and capabilities of such cells in a physiological setting are unclear. We characterized polyclonal CD8+ T cells specific for the melanocyte antigen tyrosinase-related protein 2
Externí odkaz:
https://doaj.org/article/ff7be6cef5c744868a9f63397d655dc6
Autor:
Andrew J. Sawyer, Daryl C. Drummond, Zhaohua Richard Huang, Eric Tam, Vasileios Askoxylakis, Gang Sun, Alexander Koshkaryev, Michael Santiago, Lia Luus, James F. Sampson, Ross B. Fulton, Stephanie Grabow, James J. Suchy, Anne-Sophie Dugast, Walid S. Kamoun
Supplemental figures 1, 2, and 3 and supplemental tables 1 and 2, showing the antitumor activity of EphA2-ILS-DTXp and the pharmacokinetics in multiple murine tumor models.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc53494c662779c87e655ae0c6423c80
https://doi.org/10.1158/1535-7163.22509429
https://doi.org/10.1158/1535-7163.22509429
Autor:
Andrew J. Sawyer, Daryl C. Drummond, Zhaohua Richard Huang, Eric Tam, Vasileios Askoxylakis, Gang Sun, Alexander Koshkaryev, Michael Santiago, Lia Luus, James F. Sampson, Ross B. Fulton, Stephanie Grabow, James J. Suchy, Anne-Sophie Dugast, Walid S. Kamoun
Combinations of chemotherapy with immunotherapy have seen recent clinical success, including two approvals of anti–PD-1/L1 agents in combination with taxane-based chemotherapy in non–small cell lung cancer and triple-negative breast cancer. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb2072df5200a5c5f8144cbc7a5091df
https://doi.org/10.1158/1535-7163.c.6539295.v1
https://doi.org/10.1158/1535-7163.c.6539295.v1
Autor:
Alexander Koshkaryev, Walid S. Kamoun, Gang Sun, Vasileios Askoxylakis, Lia Luus, Ross B. Fulton, James F. Sampson, Eric M. Tam, Andrew J. Sawyer, Zhaohua Richard Huang, Daryl C. Drummond, Anne-Sophie Dugast, Michael Santiago, James Suchy, Stephanie Grabow
Publikováno v:
Molecular Cancer Therapeutics. 19:270-281
Combinations of chemotherapy with immunotherapy have seen recent clinical success, including two approvals of anti–PD-1/L1 agents in combination with taxane-based chemotherapy in non–small cell lung cancer and triple-negative breast cancer. Here,
Autor:
Steven M. Leonardo, Ross B. Fulton, Kathryn A. Fraser, Mark T. Uhlik, Xiaohong Qiu, Jamie Lowe, Mark A. Matson, Keith B. Gorden, Lindsay R Jordan, Nadine R. Ottoson, Nandita Bose, Blaine Rathmann, Adria Jonas, Richard Walsh, Takashi O Kangas, Ben Harrison, Anissa S.H. Chan, Kathleen E. Ertelt, Jeremy R. Graff, Richard D. Huhn
Publikováno v:
The Journal of Immunology. 202:2945-2956
Imprime PGG (Imprime) is an i.v. administered, yeast β-1,3/1,6 glucan in clinical development with checkpoint inhibitors. Imprime-mediated innate immune activation requires immune complex formation with naturally occurring IgG anti-β glucan Abs (AB
Autor:
Roshan M. Kumar, Julie Prigent, Hombline Poullain, Ayrin Kok, Carine George, Sami Ellouze, Yun-Yueh Lu, Rebecca Silver, Clarisse Monchecourt, Ross B. Fulton, Qian Zhang, Nicola Beltraminelli, Bernhard Moser, Francisco Adrian, Liang Schweizer
Publikováno v:
Cancer Research. 82:2899-2899
Regulatory T cells (Tregs) contribute to immunosuppression within the tumor microenvironment and have been associated with poor outcomes in a range of cancers. Targeted depletion of tumor-infiltrating Tregs (TITRs) is an attractive therapeutic strate
Autor:
Stephen D O'Flanagan, Ross B. Fulton, Todd P. Knutson, Kristina S. Burrack, Katharine E. Block, Emily N Truckenbrod, Kristin R Renkema, Katie R Stagliano, Stephen C. Jameson, Arthur A Hurwitz, Henrique Borges da Silva
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09207ad9162a468bc80dd8f526cbf1a1
https://doi.org/10.7554/elife.65615.sa2
https://doi.org/10.7554/elife.65615.sa2
The identification of predictive biomarkers for patient treatment response is urgently needed to increase the probability of success of existing and novel experimental therapies. Single-cell profiling has provided novel biological insights into drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e555247109e85b82f929a1dde60c706
https://doi.org/10.1101/2021.04.13.439713
https://doi.org/10.1101/2021.04.13.439713
Autor:
Emily N Truckenbrod, Ross B. Fulton, Katharine E. Block, Katie Stagliano, Kristin R Renkema, Stephen C. Jameson, Arthur A Hurwitz, Todd P. Knutson, Henrique Borges da Silva, Kristina S. Burrack
Self-specific CD8+ T cells often escape clonal deletion, but the properties and capabilities of such cells in a physiological setting are unclear. We characterized polyclonal CD8+ T cells specific for the melanocyte antigen tyrosinase-related protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf1d93586ea9d60a6fbc2107111f530f
https://doi.org/10.1101/2020.12.16.423036
https://doi.org/10.1101/2020.12.16.423036