Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Ross A. Davey"'
Autor:
Angus Ross, Ross A. Davey, Amanda L. Hudson, Viive M. Howell, Elizabeth A. Moon, Nick Pavlakis, Stephen Clarke, Lyndsay Peters, Christopher Weir, Veronika Langova, Miles Alexander
Publikováno v:
Cancer Immunology Research. 2:469-479
Induction of antitumor immunity using autologous tumor proteins is an attractive approach to cancer therapy. However, better methods and stimulants to present these autologous proteins back to the immune system are needed. Here, we identify streptavi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae99256d50edd36b5413d7897592846c
https://doi.org/10.1158/2326-6066.cir-13-0157
https://doi.org/10.1158/2326-6066.cir-13-0157
Autor:
Steven Kao, Rozelle Harvie, Stephen Clarke, Rick Abraham, Zoltan Kerestes, Gavin Marx, Robyn Taylor, Nick Pavlakis, Martin Cullen, Ross A. Davey, Florian Paturi
Publikováno v:
Lung Cancer. 75:248-254
There is a need for new treatment strategies and prognostic markers for the management of malignant mesothelioma (MM). The activity of thalidomide/cisplatin/gemcitabine (arm A) or thalidomide alone (arm B) was investigated in two parallel phase II st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a46c8a141255aa4cacbb5d023f7e56
https://doi.org/10.1016/j.lungcan.2011.06.007
https://doi.org/10.1016/j.lungcan.2011.06.007
Autor:
Britta K. Stordal, Ross A. Davey
Publikováno v:
Current Cancer Drug Targets. 9:354-365
A systematic review of cell models of acquired drug resistance not involving genetic manipulation showed that 80% of cell models had an inverse resistance relationship between cisplatin and paclitaxel. Here we systematically review genetically modifi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c8c19b5cfd900c53fba1e8532cf4ce1
https://doi.org/10.2174/156800909788166592
https://doi.org/10.2174/156800909788166592
Autor:
Ross A. Davey, Britta K. Stordal
Publikováno v:
IUBMB Life. 60:180-184
Transfected human apoptosis signal-regulating kinase 1 (ASK1) produces a 150 kDa protein. However, we have detected endogenous ASK1 predominantly as 39 and 50 kDa C-terminal and 75 and 110 kDa N-terminal fragments in a panel of nontransfected cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::205a8a82065b0201158b1bba76e80556
https://doi.org/10.1002/iub.24
https://doi.org/10.1002/iub.24
Autor:
Valerie C. Wasinger, Mary W. Davey, Garry L. Corthals, Sheridan Henness, Joanne Banyer, Ross A. Davey, Rozelle Harvie
Publikováno v:
Radiation Research. 161:495-503
Small cell lung cancer (SCLC) initially responds well to chemotherapy and fractionated radiotherapy, but resistance to these treatments eventually develops in the vast majority of cases. To understand how resistance develops in the H69 SCLC cell line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5367af15a3e46785525de52e3ab2ba99
https://doi.org/10.1667/rr3165
https://doi.org/10.1667/rr3165
Autor:
Qi Yang, Ross A. Davey, Mary W. Davey, Craig L. Francis, Robert George Whittaker, Xanthe E Wells, Minoo J. Moghaddam, Hua-Ming Williams, Fred Widmer, Karen V Cullen
Publikováno v:
British Journal of Pharmacology. 137:1280-1286
1. Increasing the lipophilicity is a strategy often used to improve a compound's cellular uptake and retention but this may also convert it into a substrate for an ATP-dependent transporter such as P-glycoprotein or the multidrug resistance-associate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0586b78f194d921f31d808d050901d79
https://doi.org/10.1038/sj.bjp.0704983
https://doi.org/10.1038/sj.bjp.0704983
Autor:
Ross A. Davey, Patrick G. Bray, Saye Khoo, David Back, Stephen A. Ward, Kevin E. Jones, E. R. Meaden
Publikováno v:
AIDS. 15:1353-1358
Background: The multidrug transporters P-glycoprotein (P-gp) and MRP1 are functionally expressed in several subclasses of lymphocytes. HIV-1 protease inhibitors interact with both; consequently the transporters could reduce the local concentration of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::238996ee18bdd61106c1fa736630ffb9
https://doi.org/10.1097/00002030-200107270-00004
https://doi.org/10.1097/00002030-200107270-00004
Publikováno v:
British Journal of Haematology. 106:86-91
Relative to the commonly used anthracyclines, little is known about idarubicin and the development of multidrug resistance. We have previously shown the K562/IDA subline resulting from intermittent treatment of the K562 human leukaemia cell line with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46fc40cd0ed3611210eaa1321ace5fc2
https://doi.org/10.1046/j.1365-2141.1999.01494.x
https://doi.org/10.1046/j.1365-2141.1999.01494.x
Publikováno v:
Biochemical Pharmacology. 55:1283-1289
Multidrug resistance-associated protein (MRP) causes multidrug resistance (MDR) involving the anthracyclines and epipodophyllotoxins. Many studies show modulation of anthracycline levels and cytotoxicity in MRP-overexpressing cells, but there is limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4249980110e99b726c8aeb6f2ca84f43
https://doi.org/10.1016/s0006-2952(97)00562-5
https://doi.org/10.1016/s0006-2952(97)00562-5
Autor:
Mary W. Davey, Ross A. Davey
Publikováno v:
Cytotechnology. 27:237-247
Cellular models have made a significant contribution to our understanding of the molecular mechanisms of resistance to chemotherapeutic drugs. However the vast majority of these models involve cell sublines with high levels of resistance generated by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baf5ed2788331d1fa116f67b32507be3
https://doi.org/10.1023/a:1008081208312
https://doi.org/10.1023/a:1008081208312