Zobrazeno 1 - 10
of 751 335
pro vyhledávání: '"Ross A."'
Autor:
Qiliang Ding, Abigail L. Bronson, Kyna A. Byerly, Anna A. Essendrup, Elyse B. Mitchell, Cassandra K. Runke, Ross A. Rowsey, Nicole L. Hoppman
Publikováno v:
Molecular Cytogenetics, Vol 17, Iss 1, Pp 1-6 (2024)
Abstract Background Interphase fluorescence in situ hybridization (FISH) is commonly used for rapid aneuploidy detection in clinical settings. While FISH-based aneuploidy detection provides rapid results desirable for patient management, it usually o
Externí odkaz:
https://doaj.org/article/de3c40ccc0fd493fa7bf0c2e0556d1a8
Autor:
Vijaykumar Karuppiah, Dhaval Sangani, Lorraine Whaley, Robert Pengelly, Pelin Uluocak, Ricardo J. Carreira, Miriam Hock, Pietro Della Cristina, Paulina Bartasun, Paula Dobrinic, Nicola Smith, Keir Barnbrook, Ross A. Robinson, Stephen Harper
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Specificity of a T cell receptor (TCR) is determined by the combination of its interactions to the peptide and human leukocyte antigen (HLA). TCR-based therapeutic molecules have to date targeted a single peptide in the context of a single H
Externí odkaz:
https://doaj.org/article/d5245e5725e8433484357359ff41b76a
Autor:
Kanupriya R. Daga, Andrew M. Larey, Maria G. Morfin, Kailin Chen, Sara Bitarafan, Jana M. Carpenter, Hannah M. Hynds, Kelly M. Hines, Levi B. Wood, Ross A. Marklein
Publikováno v:
Journal of Biological Engineering, Vol 18, Iss 1, Pp 1-21 (2024)
Abstract Background Mesenchymal stromal cell derived extracellular vesicles (MSC-EVs) are a promising therapeutic for neuroinflammation. MSC-EVs can interact with microglia, the resident immune cells of the brain, to exert their immunomodulatory effe
Externí odkaz:
https://doaj.org/article/ed07ae149d72409faf0f21728dc5d06e
Autor:
Ashleigh Mobbs, Michelle Kahn, Gavin Williams, Benjamin F. Mentiplay, Yong-Hao Pua, Ross A. Clark
Publikováno v:
Journal of NeuroEngineering and Rehabilitation, Vol 21, Iss 1, Pp 1-11 (2024)
Abstract Background Walking impairment is a common disability post acquired brain injury (ABI), with visually evident arm movement abnormality identified as negatively impacting a multitude of psychological factors. The International Classification o
Externí odkaz:
https://doaj.org/article/f67a3065a6504928a5901c4714e4af80
Autor:
Andrew M. Larey, Thomas M. Spoerer, Kanupriya R. Daga, Maria G. Morfin, Hannah M. Hynds, Jana Carpenter, Kelly M. Hines, Ross A. Marklein
Publikováno v:
Bioactive Materials, Vol 37, Iss , Pp 153-171 (2024)
Due to their immunomodulatory function, mesenchymal stromal cells (MSCs) are a promising therapeutic with the potential to treat neuroinflammation associated with neurodegenerative diseases. This function is mediated by secreted extracellular vesicle
Externí odkaz:
https://doaj.org/article/117fb0ce6fda42fcb4c68978057c974e
Autor:
Jessica Wimberly, Aleah Nguyen, Erica Memoli, Matt Kasman, Bill Heerman, Russell Pate, Evan Sommer, Adam Sedlak, Lydia Reader, Ross A. Hammond, Shari Barkin
Publikováno v:
Frontiers in Pediatrics, Vol 12 (2024)
Childhood physical activity sets the foundation for health. While we know many factors that contribute to physical activity, there are limitations in our knowledge, especially in early childhood. Through our review, we identify gaps in existing datas
Externí odkaz:
https://doaj.org/article/0f5a5a3e508945e0983075589826c418
Autor:
Ethan P. Oxley, Nadia J. Kershaw, Cynthia Louis, Katharine J. Goodall, Maximilian M. Garwood, Skye Min Jee Ho, Veronica T.F. Voo, Hae-Young Park, Josephine Iaria, Lilian L.L. Wong, Ariel G. Lebenbaum, Stephanie Wiranata, Ee Shan Pang, Emily S.J. Edwards, Damian B. D’Silva, Jacinta Hansen, Menno C. van Zelm, Meredith O’Keeffe, P. Mark Hogarth, Nicole M. Haynes, Nicholas D. Huntington, Ian P. Wicks, Ross A. Dickins
Publikováno v:
Cell Reports, Vol 43, Iss 10, Pp 114834- (2024)
Summary: T cell surface CTLA4 sequesters the costimulatory ligands CD80 and CD86 on antigen-presenting cells (APCs) to prevent autoimmunity. Therapeutic immunosuppression by recombinant CTLA4-immunoglobulin (Ig) fusion proteins, including abatacept,
Externí odkaz:
https://doaj.org/article/6c8609b2d6c447c2abb2c3c69d1e33ba
Autor:
Gerald J. Sun, Gustavo Arango-Argoty, Gary J. Doherty, Damian E. Bikiel, Dejan Pavlovic, Allen C. Chen, Ross A. Stewart, Zhongwu Lai, Etai Jacob
Publikováno v:
iScience, Vol 27, Iss 9, Pp 110634- (2024)
Summary: System-level patient health signals, as captured by treatment-emergent adverse events (TEAEs), might contain correlates of immune checkpoint inhibitor (ICI) therapy response. Using all TEAEs and a novel machine learning modeling approach, we
Externí odkaz:
https://doaj.org/article/6446394258df4e7ba96e718b2a6519bd
Publikováno v:
Evolution: Education and Outreach, Vol 17, Iss 1, Pp 1-16 (2024)
Abstract Evolution is one of the controversial topics in biology primarily because of the perceived conflict between religion and evolution. Religiosity is one of the biggest predictors of evolution acceptance, i.e., the more religious an individual,
Externí odkaz:
https://doaj.org/article/75c0a7075ad74c3cba64f153bad46068
Autor:
Mingchao Xie, Miljenka Vuko, Jaime Rodriguez-Canales, Johannes Zimmermann, Markus Schick, Cathy O’Brien, Luis Paz-Ares, Jonathan W. Goldman, Marina Chiara Garassino, Carl M. Gay, John V. Heymach, Haiyi Jiang, J. Carl Barrett, Ross A. Stewart, Zhongwu Lai, Lauren A. Byers, Charles M. Rudin, Yashaswi Shrestha
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background We explored potential predictive biomarkers of immunotherapy response in patients with extensive-stage small-cell lung cancer (ES-SCLC) treated with durvalumab (D) + tremelimumab (T) + etoposide-platinum (EP), D + EP, or EP in the
Externí odkaz:
https://doaj.org/article/dac90161c2bf43f78841723ad0ac6b3b