Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ross VerHeul"'
Autor:
Klaus Richter, Christine Wurm, Kim Strasser, Jana Bauer, Maria Bakou, Ross VerHeul, Shawn Sternisha, Andrea Hawe, Michael Salomon, Tim Menzen, Akash Bhattacharya
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics.
Publikováno v:
Biomaterials Science. 6:863-876
Elastin-like polypeptides (ELP) are a well-known class of proteins that are being increasingly utilized in a variety of biomedical applications, due to their beneficial physicochemical properties. A unifying feature of ELP is their demonstration of a
Autor:
David H. Thompson, Wei Deng, Aditya Kulkarni, Ross VerHeul, Ryan A. Schuldt, Seok-Hee Hyun, Kyle DeFrees, Alexander Vlahu
Publikováno v:
Integrative Biology. 5:115-121
A family of branched polyrotaxanes (bPRTx(+)), threaded with multiple cationic α-cyclodextrins (α-CDs) onto a multi-armed poly(ethylene glycol) (PEG) core, were synthesized and studied as gene silencing vectors. These bPRTx(+) formed stable, positi
Publikováno v:
Protein Science. 21:1280-1287
Identifying targets of biologically active small molecules is an essential but still challenging task in drug research and chemical genetics. Energetics-based target identification is an approach that utilizes the change in the conformational stabili
Autor:
Aditya Kulkarni, Ross VerHeul, Kyle DeFrees, David H. Thompson, Alexander Vlahu, Christopher J. Collins, Ryan A. Schuldt
Publikováno v:
Biomaterials science. 1(10)
Traditionally, transfection complexes are typically formed by bulk mixing, producing particles with high polydispersity and limited control over vector size. Herein, we demonstrate the use of a commercial micro-reactor to assemble pDNA:cationic cyclo
Autor:
Ryan A. Schuldt, David H. Thompson, Vivek D. Badwaik, Alexander Vlahu, Ross VerHeul, Aditya Kulkarni, Cory Powers, Kyle DeFrees, Dinara S. Gunasekera
Publikováno v:
Biomacromolecules. 15(1)
We have previously shown that cationic-β-cyclodextrin:R-poly(vinyl alcohol)-poly(ethylene glycol) (CD+:R-PVA-PEG) pendant polymer host:guest complexes are safe and efficient vehicles for nucleic acid delivery, where R = benzylidene-linked adamantyl
Autor:
Ross VerHeul, Kyle J. Wright, Charu K. Yerneni, Seok-Hee Hyun, Kyle DeFrees, Aditya Kulkarni, Ryan A. Schuldt, David H. Thompson
RNA interference has broad therapeutic potential due to its high specificity and ability to potentially evade drug resistance. Three cationic α-cyclodextrin:poly(ethylene glycol) polyrotaxanes derived from polymer axles of different sizes (MW 2,000,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c2bd4a91f19f9ea00125096079d9c5d
https://europepmc.org/articles/PMC4083495/
https://europepmc.org/articles/PMC4083495/
Autor:
Aditya Kulkarni, Vivek Badwaik, Kyle DeFrees, Ryan A. Schuldt, Dinara S. Gunasekera, Cory Powers, Alexander Vlahu, Ross VerHeul, David H. Thompson
Publikováno v:
Biomacromolecules; Jan2014, Vol. 15 Issue 1, p12-19, 8p