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Akademický článek

Tuning recombinant protein expression to match secretion capacity

Autor: Luminita Gabriela Horga, Samantha Halliwell, Tania Selas Castiñeiras, Chris Wyre, Cristina F. R. O. Matos, Daniela S. Yovcheva, Ross Kent, Rosa Morra, Steven G. Williams, Daniel C. Smith, Neil Dixon

Publikováno v: Microbial Cell Factories, Vol 17, Iss 1, Pp 1-18 (2018)

Abstract Background The secretion of recombinant disulfide-bond containing proteins into the periplasm of Gram-negative bacterial hosts, such as E. coli, has many advantages that can facilitate product isolation, quality and activity. However, the se

Externí odkaz: https://doaj.org/article/567a76b5935f40208a61c4b153a36b6e

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Engineering Heart Valve Interfaces Using Melt Electrowriting: Biomimetic Design Strategies from Multi-Modal Imaging

Autor: Michael J. Vernon, Jason Lu, Benjamin Padman, Christopher Lamb, Ross Kent, Petra Mela, Barry Doyle, Abdul Rahman Ihdayhid, Shirley Jansen, Rodney J. Dilley, Elena M. De‐Juan‐Pardo

Publikováno v: Advanced healthcare materials.

Interfaces within biological tissues not only connect different regions but also contribute to the overall functionality of the tissue. This is especially true in the case of the aortic heart valve. Here, melt electrowriting (MEW) is used to engineer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c61223f73c58249f2bfe7d7202d53d55
https://pubmed.ncbi.nlm.nih.gov/36300603

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Reconstructing a chest wall defect with the aid of three‐dimensional printed pleural contour

Autor: Ross Kent, Christopher Cole, Michael Wagels, Caitlin O'Hare

Publikováno v: ANZ Journal of Surgery. 92:1536-1538

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd8981e730622cedc2390eb6cd0b3736
https://doi.org/10.1111/ans.17316

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An Open Source Technology Platform to Manufacture Hydrogel-Based 3D Culture Models in an Automated and Standardized Fashion

Autor: Dietmar W. Hutmacher, Christoph Meinert, Nathalie Bock, Lukas Gaats, Ross Kent, Melanie Kahl, Sebastian Eggert

Publikováno v: Journal of visualized experiments : JoVE. (181)

Current mixing steps of viscous materials rely on repetitive and time-consuming tasks which are performed mainly manually in a low throughput mode. These issues represent drawbacks in workflows that can ultimately result in irreproducibility of resea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5132f544bea19a4e49f97d1cb96c5983
https://pubmed.ncbi.nlm.nih.gov/35435917

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Development of High-Performance Whole Cell Biosensors Aided by Statistical Modeling

Autor: Ross Kent, Neil Dixon, Leopoldo F. M. Machado, Adokiye Berepiki

Publikováno v: ACS Synthetic Biology
Berepiki, A, Kent, R, Machado, L F M & Dixon, N 2020, ' Development of High-Performance Whole Cell Biosensors Aided by Statistical Modeling ', ACS Synthetic Biology, vol. 9, no. 3, pp. 576-589 . https://doi.org/10.1021/acssynbio.9b00448

Whole cell biosensors are genetic systems that link the presence of a chemical, or other stimulus, to a user-defined gene expression output for applications in sensing and control. However, the gene expression level of biosensor regulatory components

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa75f3be6573f48e3db29fc1a075107e
http://europepmc.org/articles/PMC7146887

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Contemporary tools for regulating gene expression in bacteria

Autor: Ross Kent, Neil Dixon

Publikováno v: Kent, R & Dixon, N 2019, ' Contemporary tools for regulating gene expression in bacteria ', Trends in Biotechnology . https://doi.org/10.1016/j.tibtech.2019.09.007

Insights from novel mechanistic paradigms in gene expression control have led to the development of new gene expression systems for bioproduction, control, and sensing applications. Coupled with a greater understanding of synthetic burden and modern

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94b190187623e476289689cc8b0d6fc
https://www.research.manchester.ac.uk/portal/en/publications/contemporary-tools-for-regulating-gene-expression-in-bacteria(b224ad8f-45d1-4e9f-a906-6513466391a7).html

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Rationalizing Context-Dependent Performance of Dynamic RNA Regulatory Devices

Autor: Samantha Halliwell, Neil Dixon, Neil Swainston, Ross Kent, Kate Young

Publikováno v: ACS synthetic biology. 7(7)

The ability of RNA to sense, regulate, and store information is an attractive attribute for a variety of functional applications including the development of regulatory control devices for synthetic biology. RNA folding and function is known to be hi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d8e37b1057b982b90116c4489c64560
https://pubmed.ncbi.nlm.nih.gov/29928800

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