J-domain proteins: From molecular mechanisms to diseases.

Autor: Marszalek J; Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Abrahama 58, Gdansk 80-307, Poland., De Los Rios P; Institute of Physics, School of Basic Sciences, École Polytechnique Fédérale de Lausanne - EPFL, Lausanne CH 1015, Switzerland; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne - EPFL, Lausanne CH 1015, Switzerland., Cyr D; Department of Cell Biology and Physiology, School of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA., Mayer MP; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg 69120, Germany., Adupa V; Zernike Institute for Advanced Materials, University of Groningen, Groningen, The Netherlands., Andréasson C; Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Stockholm S-10691, Sweden., Blatch GL; Biomedical Research and Drug Discovery Research Group, Faculty of Health Sciences, Higher Colleges of Technology, Sharjah, United Arab Emirates; The Vice Chancellery, The University of Notre Dame Australia, Fremantle, Western Australia, Australia; Biomedical Biotechnology Research Unit, Department of Biochemistry and Microbiology, Rhodes University, Grahamstown, South Africa., Braun JEA; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada., Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA., Bukau B; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg 69120, Germany., Chapple JP; William Harvey Research Institute, Barts and the London School of Medicine, Queen Mary University of London, London EC1M 6BQ, United Kingdom., Conz C; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Dementin S; Aix Marseille Univ, CNRS, BIP UMR 7281, IMM, 31 Chemin Joseph Aiguier, Marseille 13402, France., Genevaux P; Laboratoire de Microbiologie et Génétique Moléculaires (LMGM), Centre de Biologie Intégrative (CBI), Université de Toulouse, CNRS, Université Toulouse III - Paul Sabatier (UT3), Toulouse, France., Genest O; Aix Marseille Univ, CNRS, BIP UMR 7281, IMM, 31 Chemin Joseph Aiguier, Marseille 13402, France., Goloubinoff P; Department of Plant Molecular Biology, Faculty of Biology and Medicine, Lausanne University, Lausanne 1015, Switzerland., Gestwicki J; Department of Pharmaceutical Chemistry and the Institute for Neurodegenerative Diseases, University of California San Francisco, San Francisco, CA 94308, USA., Hammond CM; Novo Nordisk Foundation Center for Protein Research (CPR), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark; Department of Molecular & Clinical Cancer Medicine, Institute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, United Kingdom., Hines JK; Department of Chemistry, Lafayette College, Easton, PA, USA., Ishikawa K; Center for Molecular Biology of Heidelberg University (ZMBH), Heidelberg 69120, Germany., Joachimiak LA; Center for Alzheimer's and Neurodegenerative Diseases, UT Southwestern Medical Center, Dallas, TX, USA; Peter O'Donnell Jr Brain Institute, UT Southwestern Medical Center, Dallas, TX, USA., Kirstein J; Leibniz Institute on Aging - Fritz Lipmann Institute and Institute of Biochemistry and Biophysics, Friedrich Schiller University Jena, Jena 07745, Germany., Liberek K; Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Abrahama 58, Gdansk 80-307, Poland., Mokranjac D; LMU Munich, Biocenter-Cell Biology, Großhadernerstr. 2, Planegg-Martinsried 82152, Germany., Nillegoda N; Australian Regenerative Medicine Institute, Monash University, Clayton, Victoria, Australia; Centre for Dementia and Brain Repair at the Australian Regenerative Medicine Institute, Monash University, Melbourne, Victoria, Australia., Ramos CHI; Institute of Chemistry, University of Campinas-UNICAMP, P.O. Box 6154, 13083-970 Campinas, SP, Brazil., Rebeaud M; Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne - EPFL, Lausanne CH 1015, Switzerland., Ron D; University of Cambridge, Cambridge CB2 0XY, United Kingdom., Rospert S; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Sahi C; Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal, Bhopal, Madhya Pradesh, India; IISER Bhopal, Room Number 117, AB3, Bhopal Bypass Road, Bhopal 462066, Madhya Pradesh, India., Shalgi R; Department of Biochemistry, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa 31096, Israel., Tomiczek B; Intercollegiate Faculty of Biotechnology, University of Gdansk and Medical University of Gdansk, Abrahama 58, Gdansk 80-307, Poland., Ushioda R; Department of Molecular Biosciences, Faculty of Life Sciences, Kyoto Sangyo University, Kyoto 603-8555, Japan., Ustyantseva E; Department of Biomedical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Ye Y; National Institute of Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA., Zylicz M; Foundation for Polish Science, Warsaw 02-611, Poland., Kampinga HH; Department of Biomedical Sciences, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands. Electronic address: h.h.kampinga@umcg.nl.

Publikováno v: Cell stress & chaperones [Cell Stress Chaperones] 2024 Feb; Vol. 29 (1), pp. 21-33. Date of Electronic Publication: 2023 Dec 23.

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast

Autor: Zhang, Y., Laurentiis, E., Bohnsack, K., Wahlig, M., Ranjan, N., Gruseck, S., Hackert, P., Wölfle, T., Rodnina, M., Schwappach, B., Rospert, S.

Publikováno v: Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)

The guided entry of tail-anchored proteins (GET) pathway assists in the posttranslational delivery of tail-anchored proteins, containing a single C-terminal transmembrane domain, to the ER. Here we uncover how the yeast GET pathway component Get4/5 f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::56f4de2243fc1723becdfa96ffa7d680
https://pubmed.ncbi.nlm.nih.gov/33542241

Snf1/AMPK fine-tunes TORC1 signaling in response to glucose starvation.

Autor: Caligaris M; Department of Biology, University of Fribourg, Fribourg, Switzerland., Nicastro R; Department of Biology, University of Fribourg, Fribourg, Switzerland., Hu Z; Department of Biology, University of Fribourg, Fribourg, Switzerland., Tripodi F; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy., Hummel JE; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany., Pillet B; Department of Biology, University of Fribourg, Fribourg, Switzerland., Deprez MA; Functional Biology, KU Leuven, Heverlee, Belgium., Winderickx J; Functional Biology, KU Leuven, Heverlee, Belgium., Rospert S; Institute of Biochemistry and Molecular Biology, Faculty of Medicine, University of Freiburg, Freiburg, Germany.; Signalling Research Centres BIOSS and CIBSS, University of Freiburg, Freiburg, Germany., Coccetti P; Department of Biotechnology and Biosciences, University of Milano-Bicocca, Milano, Italy., Dengjel J; Department of Biology, University of Fribourg, Fribourg, Switzerland., De Virgilio C; Department of Biology, University of Fribourg, Fribourg, Switzerland.

Publikováno v: ELife [Elife] 2023 Feb 07; Vol. 12. Date of Electronic Publication: 2023 Feb 07.

Ribosome-bound Get4/5 facilitates the capture of tail-anchored proteins by Sgt2 in yeast.

Autor: Zhang Y; Institute of Biochemistry and Molecular Biology, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany., De Laurentiis E; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany., Bohnsack KE; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany., Wahlig M; Institute of Biochemistry and Molecular Biology, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany., Ranjan N; Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany., Gruseck S; Institute of Biochemistry and Molecular Biology, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany., Hackert P; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany., Wölfle T; Institute of Biochemistry and Molecular Biology, University of Freiburg, Freiburg, Germany.; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany., Rodnina MV; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany.; Max-Planck Institute for Biophysical Chemistry, Göttingen, Germany., Schwappach B; Department of Molecular Biology, University Medical Center Göttingen, Göttingen, Germany. blanche.schwappach@med.uni-goettingen.de.; Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany. blanche.schwappach@med.uni-goettingen.de., Rospert S; Institute of Biochemistry and Molecular Biology, University of Freiburg, Freiburg, Germany. sabine.rospert@biochemie.uni-freiburg.de.; BIOSS Centre for Biological Signaling Studies, University of Freiburg, Freiburg, Germany. sabine.rospert@biochemie.uni-freiburg.de.

Publikováno v: Nature communications [Nat Commun] 2021 Feb 04; Vol. 12 (1), pp. 782. Date of Electronic Publication: 2021 Feb 04.

Pam16 and Pam18 were repurposed during Trypanosoma brucei evolution to regulate the replication of mitochondrial DNA.

Autor: von Känel, Corinne¹ (AUTHOR), Stettler, Philip¹ (AUTHOR), Esposito, Carmela¹ (AUTHOR), Berger, Stephan¹ (AUTHOR), Amodeo, Simona¹ (AUTHOR), Oeljeklaus, Silke² (AUTHOR), Calderaro, Salvatore¹ (AUTHOR), Durante, Ignacio M.³ (AUTHOR), Rašková, Vendula^3,4 (AUTHOR), Warscheid, Bettina² (AUTHOR) bettina.warscheid@uni-wuerzburg.de, Schneider, André¹ (AUTHOR) andre.schneider@unibe.ch

Publikováno v: PLoS Biology. 8/15/2024, Vol. 22 Issue 8, p1-33. 33p.