Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Roslyn Stella Thelingwani"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract We analyzed parentage data collected over a ten-year period in a Zimbabwean DNA testing laboratory. Parentage case types, prevalence, exclusion data, mutations rates and observed genotyping irregularities were analyzed. We report analysis re
Externí odkaz:
https://doaj.org/article/2bc1c626ae8b46ffaa53468ad0e1371b
Autor:
Misheck Mudyiwa, Manju Sharma, Samarendra Kumar Ray, Collen Masimirembwa, Roslyn Stella Thelingwani
Publikováno v:
Scientific African, Vol 21, Iss , Pp e01835- (2023)
Herbs have the potential to interact with conventional medicines or each other upon concurrent administration. This can be at the level of absorption, distribution, metabolism and excretion (ADME). With an estimation that 80% of the population in poo
Externí odkaz:
https://doaj.org/article/2c083dd892a14e4491df024163a96371
Autor:
Comfort Ropafadzo Kanji, Bianza Tinotenda Mbavha, Collen Masimirembwa, Roslyn Stella Thelingwani
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0292131 (2023)
Pharmacogenomic testing may be used to improve treatment outcomes and reduce the frequency of adverse drug reactions (ADRs). Population specific, targeted pharmacogenetics (PGx) panel-based testing methods enable sensitive, accurate and economical im
Externí odkaz:
https://doaj.org/article/461a1dcfa02048deaf9403614c1881f1
Autor:
Comfort Ropafadzo Kanji, Bianza Tinotenda Mbavha, Collen Masimirembwa, Roslyn Stella Thelingwani
Publikováno v:
PLoS ONE, Vol 18, Iss 10 (2023)
Externí odkaz:
https://doaj.org/article/5d7dbd1440a94c989de5c3ad97d5b5aa
Autor:
Chenai Sheilla Mutiti, Nyasha Nicole Kapungu, Comfort Ropafadzo Kanji, Nadina Stadler, Julia Stingl, Charles Nhachi, James Hakim, Collen Masimirembwa, Roslyn Stella Thelingwani
Publikováno v:
Pharmacology Research & Perspectives, Vol 9, Iss 3, Pp n/a-n/a (2021)
Abstract We conducted a clinical study to determine the effect of efavirenz and ritonavir on the pharmacokinetics of R‐ and S‐PZQ in healthy male participants. This was toward evaluating the risk of drug‐drug interactions, which may occur after
Externí odkaz:
https://doaj.org/article/a7d29bf87083467da4b0edc98c236270
Autor:
Nyasha Nicole Kapungu, Xueqing Li, Charles Nhachi, Collen Masimirembwa, Roslyn Stella Thelingwani
Publikováno v:
Pharmacology Research & Perspectives, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Racemic praziquantel (PZQ) is the drug of choice for the treatment of schistosomiasis. R‐Praziquantel (R‐PZQ) has been shown as the therapeutic form, whereas S‐PZQ is less efficacious and responsible for the bitter taste of the tablet.
Externí odkaz:
https://doaj.org/article/a116c4be1ee24c32a11252a9699ae55c
Autor:
Xue-Qing Li, Roslyn Stella Thelingwani, Leif Bertilsson, Ulf Diczfalusy, Tommy B. Andersson, Collen Masimirembwa
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 6, p 457 (2021)
In this study, we aimed to evaluate the utility of endogenous 1β-hydroxy-deoxycholic acid/total deoxycholic acid ratio (1β-OH-DCA/ToDCA) in spot urine as a surrogate marker of cytochrome P450 3A (CYP3A) activity in the assessment inhibition-based d
Externí odkaz:
https://doaj.org/article/0089ad695ac84731b383eef8fdea96ef