Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Roslyn M Bill"'
Autor:
Philip Kitchen, Fredrik Öberg, Jennie Sjöhamn, Kristina Hedfalk, Roslyn M Bill, Alex C Conner, Matthew T Conner, Susanna Törnroth-Horsefield
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143027 (2015)
Aquaporin membrane protein channels mediate cellular water flow. Human aquaporin 5 (AQP5) is highly expressed in the respiratory system and secretory glands where it facilitates the osmotically-driven generation of pulmonary secretions, saliva, sweat
Externí odkaz:
https://doaj.org/article/999e92a6256e47d0a85df8d89f6d84c8
Autor:
Nicklas Bonander, Mohammed Jamshad, Dominik Oberthür, Michelle Clare, James Barwell, Ke Hu, Michelle J Farquhar, Zania Stamataki, Helen J Harris, Karsten Dierks, Timothy R Dafforn, Christian Betzel, Jane A McKeating, Roslyn M Bill
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64517 (2013)
The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1, also associates with tetraspanin CD81 as part of a receptor complex that is essential for hepa
Externí odkaz:
https://doaj.org/article/e3184b68e5bd4fba814fbcee679036f8
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45006 (2012)
The dipeptide L-carnosine (β-alanyl-L-histidine) has been described as enigmatic: it inhibits growth of cancer cells but delays senescence in cultured human fibroblasts and extends the lifespan of male fruit flies. In an attempt to understand these
Externí odkaz:
https://doaj.org/article/7915666cf77d43acb2ec0fad85aca619
Publikováno v:
Electronic Journal of Biotechnology, Vol 66, Iss , Pp 1-16 (2023)
Background: Cellulose is an organic carbon source that can be used as a sustainable alternative for energy, materials, and chemicals. However, the substantial challenge of converting it into soluble sugars remains a major obstacle in its use as a bio
Externí odkaz:
https://doaj.org/article/725caf027e2e4cdfb0358c3f9ddb60d1
Autor:
Jonas Hyld Steffen, Julie Winkel Missel, Tamim Al-Jubair, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Susanna Törnroth-Horsefield, Pontus Gourdon
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101312- (2022)
Summary: Aquaporins (AQPs) are water channels embedded in the cell membrane that are critical in maintaining water homeostasis. We describe a protocol for determining the water permeation capacity of AQPs reconstituted into proteoliposomes. Using a s
Externí odkaz:
https://doaj.org/article/1a3eb367bcee4d1c9d47e268d3434edd
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101298- (2022)
Summary: Aquaporins (AQPs) are membrane-bound water channels that play crucial roles in maintaining the water homeostasis of the human body. Here, we present a protocol for high-yield recombinant expression of human AQPs in the methylotropic yeast Pi
Externí odkaz:
https://doaj.org/article/5ab3c0de13584bbd895ba84cf305b169
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101316- (2022)
Summary: Aquaporin water channels (AQPs) are membrane proteins that maintain cellular water homeostasis. The interactions between human AQPs and other proteins play crucial roles in AQP regulation by both gating and trafficking. Here, we describe a p
Externí odkaz:
https://doaj.org/article/cd7e6ed9d36d4404b5a0e95d3eb6b738
Autor:
Philip Kitchen, Mootaz M. Salman, Mohammed Abir-Awan, Tamim Al-Jubair, Susanna Törnroth- Horsefield, Alex C. Conner, Roslyn M. Bill
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100157- (2020)
Summary: Aquaporins (AQPs) are membrane channel proteins that facilitate the movement of water down osmotic gradients across biological membranes. This protocol allows measurements of AQP-mediated water transport across the plasma membrane of live ma
Externí odkaz:
https://doaj.org/article/09f4c22380c54f5eb2674a12b11cd820
Publikováno v:
Applied Sciences, Vol 11, Iss 11, p 4877 (2021)
A triple mutant of NADP(H)-dependent malate dehydrogenase from thermotolerant Thermococcus kodakarensis has an altered cofactor preference for NAD+, as well as improved malate production compared to wildtype malate dehydrogenase. By combining mutant
Externí odkaz:
https://doaj.org/article/912a3d2a0f894695b2165dfc35924485
Autor:
Mootaz M. Salman, Zaid Al-Obaidi, Philip Kitchen, Andrea Loreto, Roslyn M. Bill, Richard Wade-Martins
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9, p 4688 (2021)
Neurodegenerative diseases (NDs) including Alzheimer’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, and Huntington’s disease are incurable and affect millions of people worldwide. The development of treatments for this unmet cli
Externí odkaz:
https://doaj.org/article/0d12a2e1d3e04e1ba60376cf7a28bfa0