Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Roslyn A. Kemp"'
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Objective Human intestinal organoids (hIOs) have potential as a model for investigating intestinal diseases. The hIO system faces logistic challenges including limited access to biopsies or low expression of epithelial cell types. Previous r
Externí odkaz:
https://doaj.org/article/a26493641dbb4c87aa95e26901b2b9b5
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-10 (2020)
Abstract Mouse models are invaluable tools for cancer immunology research. However, there are differences in the immune response to the tumour depending on the model used, and these differences are not often characterised on their own. Instead they a
Externí odkaz:
https://doaj.org/article/1fd3a379673d4dbf8eae8abde4ca09bb
Autor:
Samuel E. Norton, Julia K. H. Leman, Tiffany Khong, Andrew Spencer, Barbara Fazekas de St Groth, Helen M. McGuire, Roslyn A. Kemp
Publikováno v:
BMC Bioinformatics, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background The advent of mass cytometry has dramatically increased the parameter limit for immunological analysis. New approaches to analysing high parameter cytometry data have been developed to ease analysis of these complex datasets. Many
Externí odkaz:
https://doaj.org/article/58fe9b4b0d7a4a0ba9e8a36335dbeb85
Publikováno v:
Frontiers in Medicine, Vol 6 (2020)
Inflammatory Bowel Diseases (IBD) are difficult to model as freshly acquired tissues are short-lived, provide data as a snapshot in time, and are not always accessible. Many patients with IBD are non-responders to first-line treatments, and responder
Externí odkaz:
https://doaj.org/article/fbe13b4e28064edb9a11b5e5f9534012
Autor:
Samuel E Norton, Tiffany Khong, Malarmathy Ramachandran, Andrew J Highton, Kirsten A Ward‐Hartstonge, Jake Shortt, Andrew Spencer, Roslyn A Kemp
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Objectives Lenalidomide (LEN) is used to treat multiple myeloma (MM) and shows in vitro synergy with KappaMab (KM), a chimeric antibody specific for Kappa Myeloma antigen, an antigen exclusively expressed on the surface of kappa‐restricted
Externí odkaz:
https://doaj.org/article/3c64e8fff2fb416e86b78486d31102b4
Autor:
Kerry Taylor, Malarmathy Ramachandran, Anna Kalff, Hang Quach, Andrew J. Mitchell, James D'Rozario, Jane Estell, Tiffany Khong, Samuel E Norton, John V. Reynolds, Andrew Spencer, P. Joy Ho, Roslyn A. Kemp, Peter Mollee, Nola Kennedy
Publikováno v:
Haematologica
Publikováno v:
Probiotics and Antimicrobial Proteins. 13:1521-1529
Streptococcus salivarius K12 is an oral probiotic known to contribute to protection against oral pathogenic bacteria in humans. Studies of immune responses to S. salivarius K12 have focused on the oral cavity, and systemic immune responses have not y
Autor:
Hamish CK Angus, Paulo CM Urbano, Gemma A Laws, Shijun Fan, Safina Gadeock, Michael Schultz, Grant Butt, Andrew J Highton, Roslyn A Kemp
Publikováno v:
Clinical & Translational Immunology. 11
Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised intestinal epithelial ba
Publikováno v:
Probiotics and antimicrobial proteins. 13(6)
Streptococcus salivarius K12 is an oral probiotic known to contribute to protection against oral pathogenic bacteria in humans. Studies of immune responses to S. salivarius K12 have focused on the oral cavity, and systemic immune responses have not y
Autor:
Roslyn A. Kemp, Virginia Niemi, Lyn M. Wise, Aziz Aiderus, Anita K. Dunbier, Jody Hazlett, Katelyn Powell
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Background Oestrogen receptor-positive (ER+) breast cancer is commonly treated using endocrine therapies such as aromatase inhibitors which block synthesis of oestradiol, but the influence of this therapy on the immune composition of breast tumours h