Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Roslyn A Kemp"'
Autor:
Samuel E Norton, Tiffany Khong, Malarmathy Ramachandran, Andrew J Highton, Kirsten A Ward‐Hartstonge, Jake Shortt, Andrew Spencer, Roslyn A Kemp
Publikováno v:
Clinical & Translational Immunology, Vol 12, Iss 12, Pp n/a-n/a (2023)
Abstract Objectives Lenalidomide (LEN) is used to treat multiple myeloma (MM) and shows in vitro synergy with KappaMab (KM), a chimeric antibody specific for Kappa Myeloma antigen, an antigen exclusively expressed on the surface of kappa‐restricted
Externí odkaz:
https://doaj.org/article/3c64e8fff2fb416e86b78486d31102b4
Autor:
Hamish CK Angus, Paulo CM Urbano, Gemma A Laws, Shijun Fan, Safina Gadeock, Michael Schultz, Grant Butt, Andrew J Highton, Roslyn A Kemp
Publikováno v:
Clinical & Translational Immunology, Vol 11, Iss 8, Pp n/a-n/a (2022)
Abstract Objectives Crohn's disease (CD) initiation and pathogenesis are believed to involve an environmental trigger in a genetically susceptible person that results in an immune response against commensal gut bacteria, leading to a compromised inte
Externí odkaz:
https://doaj.org/article/50612b2adcad499cb4b121421df98e85
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Immune-suppressive cell populations impair anti-tumor immunity and can contribute to the failure of immune therapeutic approaches. We hypothesized that the non-steroidal anti-inflammatory drug (NSAID) licofelone, a dual COX-2/5-LO inhibitor, would im
Externí odkaz:
https://doaj.org/article/95fe30968db04982b3aefe3aa6dae64e
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-8 (2022)
Abstract Objective Human intestinal organoids (hIOs) have potential as a model for investigating intestinal diseases. The hIO system faces logistic challenges including limited access to biopsies or low expression of epithelial cell types. Previous r
Externí odkaz:
https://doaj.org/article/a26493641dbb4c87aa95e26901b2b9b5
Autor:
Kerry Taylor, Malarmathy Ramachandran, Anna Kalff, Hang Quach, Andrew J. Mitchell, James D'Rozario, Jane Estell, Tiffany Khong, Samuel E Norton, John V. Reynolds, Andrew Spencer, P. Joy Ho, Roslyn A. Kemp, Peter Mollee, Nola Kennedy
Publikováno v:
Haematologica
Publikováno v:
Probiotics and Antimicrobial Proteins. 13:1521-1529
Streptococcus salivarius K12 is an oral probiotic known to contribute to protection against oral pathogenic bacteria in humans. Studies of immune responses to S. salivarius K12 have focused on the oral cavity, and systemic immune responses have not y
Publikováno v:
Laboratory Animal Research, Vol 36, Iss 1, Pp 1-10 (2020)
Laboratory Animal Research
Laboratory Animal Research
Mouse models are invaluable tools for cancer immunology research. However, there are differences in the immune response to the tumour depending on the model used, and these differences are not often characterised on their own. Instead they are often
Publikováno v:
Probiotics and antimicrobial proteins. 13(6)
Streptococcus salivarius K12 is an oral probiotic known to contribute to protection against oral pathogenic bacteria in humans. Studies of immune responses to S. salivarius K12 have focused on the oral cavity, and systemic immune responses have not y
Autor:
Roslyn A. Kemp, Virginia Niemi, Lyn M. Wise, Aziz Aiderus, Anita K. Dunbier, Jody Hazlett, Katelyn Powell
Publikováno v:
Breast Cancer Research : BCR
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Breast Cancer Research, Vol 23, Iss 1, Pp 1-15 (2021)
Background Oestrogen receptor-positive (ER+) breast cancer is commonly treated using endocrine therapies such as aromatase inhibitors which block synthesis of oestradiol, but the influence of this therapy on the immune composition of breast tumours h
Autor:
Kirsten A Ward-Hartstonge, Roslyn A. Kemp, John L. McCall, Fran Munro, Edward S Taylor, Samuel E Norton, Julia Kh Leman, Helen M. McGuire, Barbara Fazekas de St Groth, Michael A. Black
Publikováno v:
The Journal of Immunology. 202:1871-1884
T cell infiltration of tumors plays an important role in determining colorectal cancer disease progression and has been incorporated into the Immunoscore prognostic tool. In this study, mass cytometry was used to demonstrate a significant increase in