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of 15
pro vyhledávání: '"Roslyn, Davis"'
Autor:
Adrien Molinas, Lucie Desmoulins, Roslyn Davis, Hong Gao, Ryousuke Satou, Andrei Derbenev, Andrea Zsombok
Publikováno v:
Physiology. 38
Stimulation of hepatic sympathetic nerves increases glucose production and glycogenolysis. Activity of pre-sympathetic neurons in the paraventricular nucleus (PVN) of the hypothalamus and in the ventrolateral and ventromedial medulla (VLM/VMM) largel
Publikováno v:
Physiology. 38
The sympathetic nervous system plays an important role in the maintenance of hepatic glucose homeostasis, through stimulating glucose production and glycogenolysis. Pre-sympathetic neurons in the brainstem and hypothalamus govern the sympathetic outp
Autor:
Roslyn, Davis, Elena, Velkoska, Helen, McCallum, Belinda, Majcen, Andreas, Gille, Bronwyn A, Kingwell, Kirstee, Martin
Publikováno v:
Journal of Immunological Methods. 513:113411
There are numerous challenges encountered during clinical testing for an immunogenic response to a plasma-derived therapeutic. Distinguishing between antibodies that recognize endogenous versus therapeutic protein can be particularly difficult. This
Autor:
Thomas Gentinetta, John D. Belcher, Valérie Brügger-Verdon, Jacqueline Adam, Tanja Ruthsatz, Joseph Bain, Daniel Schu, Lisa Ventrici, Monika Edler, Hadi Lioe, Kalpeshkumar Patel, Chunsheng Chen, Julia Nguyen, Fuad Abdulla, Ping Zhang, Andreas Wassmer, Meena Jain, Marcel Mischnik, Matthias Pelzing, Kirstee Martin, Roslyn Davis, Svetlana Didichenko, Alexander Schaub, Nathan Brinkman, Eva Herzog, Adrian Zürcher, Gregory M. Vercellotti, Gregory J. Kato, Gerald Höbarth
Publikováno v:
Journal of Clinical Medicine, Vol 11, Iss 630, p 630 (2022)
Journal of Clinical Medicine; Volume 11; Issue 3; Pages: 630
Journal of Clinical Medicine; Volume 11; Issue 3; Pages: 630
People living with sickle cell disease (SCD) face intermittent acute pain episodes due to vaso-occlusion primarily treated palliatively with opioids. Hemolysis of sickle erythrocytes promotes release of heme, which activates inflammatory cell adhesio
Publikováno v:
The AAPS journal. 22(3)
This article provides a theoretical case-study risk assessment report for a low-risk monoclonal antibody (mAb) therapeutic. In terms of risk, there are considerations around risks to safety, but also risks regarding effects on pharmacokinetics (PK),
Autor:
Samuel D. Wright, Denise D'Andrea, Andreas Gille, Rachael Easton, Roslyn Davis, Charles L. Shear
Publikováno v:
The Journal of Clinical Pharmacology. 54:301-310
CSL112 is apoA-I purified from human plasma and reconstituted with phosphatidylcholine (PC) to form high-density lipoprotein (HDL)-particles suitable for infusion. CSL112 is in development for the potential treatment of acute coronary syndromes (ACS)
Akademický článek
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Autor:
John Cooper Cox, Roslyn Davis, Sigrid Elisabet Sjolander, Debbie Drane, Martin J. Pearse, Lorraine Beezum
Publikováno v:
Vaccine. 19:4072-4080
Intranasal administration of vaccines is preferred for induction of mucosal immune responses. In this study, mice were immunised intranasally and subcutaneously with influenza-immuno stimulating complexes (influenza-ISCOM). The intranasal dose was 15
Autor:
Rachael, Easton, Andreas, Gille, Denise, D'Andrea, Roslyn, Davis, Samuel D, Wright, Charles, Shear
Publikováno v:
Journal of clinical pharmacology. 54(3)
CSL112 is apoA-I purified from human plasma and reconstituted with phosphatidylcholine (PC) to form high-density lipoprotein (HDL)-particles suitable for infusion. CSL112 is in development for the potential treatment of acute coronary syndromes (ACS)
Autor:
Martin J. Pearse, Roslyn Davis, Alan Coulter, Debbie Drane, David Ryan, R.D. Harris, John Cooper Cox, Phil Sutton, Steve Rockman
Publikováno v:
Vaccine. 21(9-10)
Mucosal delivery of inactivated vaccines that are able to elicit protective immune responses against respiratory diseases has been a long time goal of vaccinologists. Such vaccines would enable a more appropriate means of vaccination against respirat