Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Roslin J. Thoppil"'
Publikováno v:
Methods Mol Biol
Methods in Molecular Biology ISBN: 9781071602188
Methods in Molecular Biology ISBN: 9781071602188
Cell polarization is important for multiple physiological processes. In motile cells, microtubules (MTs) are organized as a polarized array, which is to a large extent comprised of Golgi-derived MTs (GDMTs), which asymmetrically extend toward the cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3fdd4054af78504901613e174f4623
https://pubmed.ncbi.nlm.nih.gov/31879905
https://pubmed.ncbi.nlm.nih.gov/31879905
Autor:
Ravi K. Adapala, Anantha K Kanugula, Roslin J. Thoppil, Charles K. Thodeti, Sailaja Paruchuri, Holly C. Cappelli
Publikováno v:
Oncotarget
Targeting angiogenesis is considered a promising therapy for cancer. Besides curtailing soluble factor mediated tumor angiogenesis, understanding the unexplored regulation of angiogenesis by mechanical cues may lead to the identification of novel the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e8dc6407a5d172299248f0adb6abbe
http://europepmc.org/articles/PMC5041949
http://europepmc.org/articles/PMC5041949
Autor:
Kaustabh Ghosh, Sailaja Paruchuri, J. G. Meszaros, Charles K. Thodeti, Ravi K. Adapala, Holly C. Cappelli, Roslin J. Thoppil, Andrew C. Dudley, Venkateshwar G. Keshamouni, William M. Chilian, Donald E. Ingber, Michael Klagsbrun
Publikováno v:
Oncogene
Oncogene, vol 35, iss 3
Oncogene, vol 35, iss 3
Tumor vessels are characterized by abnormal morphology and hyperpermeability that together cause inefficient delivery of chemotherapeutic agents. Although vascular endothelial growth factor has been established as a critical regulator of tumor angiog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dde734bb873714b72ea004aa03b1b0a
https://doi.org/10.1038/onc.2015.83
https://doi.org/10.1038/onc.2015.83
Autor:
Roslin J. Thoppil, Irina Kaverina, Anna A. W. M. Sanders, Kevin Chang, Xiaodong Zhu, William R. Holmes
Publikováno v:
Molecular Biology of the Cell
GDMT (Golgi-derived microtubule) asymmetry is required for polarized cell motility, but its origin is elusive. Combining experimental and computational approaches, we find that GDMTs arise from spatially restricted hotspots that rely on γ-TuNA (γ-T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39053978af7e6046602c1ef7718ab52
https://pubmed.ncbi.nlm.nih.gov/28931596
https://pubmed.ncbi.nlm.nih.gov/28931596
Publikováno v:
International Journal of Cancer. 133:1054-1063
Breast cancer represents one of the most frequently diagnosed cancers and predominant causes of death in women worldwide. The value of preventive therapy to limit the devastating impact of breast cancer is well established. Various plant triterpenoid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0a03c8aa41f6784014d3870bd92cbd
https://doi.org/10.1002/ijc.28108
https://doi.org/10.1002/ijc.28108
Publikováno v:
Pharmaceutical Biology. 51:668-674
Phytochemicals are produced by desert plants to protect themselves against stressful environments. They have been shown to be useful in preventing and fighting adverse pathophysiological conditions and complex diseases, including cancer. Although man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e228fd1470125602732ee9231c707d57
https://doi.org/10.3109/13880209.2012.749922
https://doi.org/10.3109/13880209.2012.749922
Autor:
J. Gary Meszaros, William M. Chilian, Daniel J. Luther, Ravi K. Adapala, Sailaja Paruchuri, Charles K. Thodeti, Roslin J. Thoppil
Publikováno v:
Journal of Molecular and Cellular Cardiology. 54:45-52
The phenotypic switch underlying the differentiation of cardiac fibroblasts into hypersecretory myofibroblasts is critical for cardiac remodeling following myocardial infarction. Myofibroblasts facilitate wound repair in the myocardium by secreting a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f36d037ef42acd38225496737a9c906c
https://doi.org/10.1016/j.yjmcc.2012.10.016
https://doi.org/10.1016/j.yjmcc.2012.10.016
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 36
Angiogenesis, the formation new blood vessels from pre-existing ones, is critical for maintenance of normal cardiovascular physiology. However, excessive or insufficient angiogenesis can contribute to various diseases including cancer, atherosclerosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe3c7c5e06fdaaaf7e2563774389a906
https://doi.org/10.1161/atvb.36.suppl_1.364
https://doi.org/10.1161/atvb.36.suppl_1.364
Autor:
Roslin J. Thoppil, Nicholas A. Novotny, Jaclyn A. Kruse, Altaf S. Darvesh, Anupam Bishayee, Abhijeet Waghray
Publikováno v:
Current Cancer Drug Targets. 12:1191-1232
Hepatocellular carcinoma (HCC), one of the most common and lethal cancers, is a growing menace in modern society. Until recently, the majority of detected cases of liver cancer have been found in the developing nations of Asia and Africa; however, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1c1c53fe667d794f6a99b1be86ce50e
https://doi.org/10.2174/15680096112091191
https://doi.org/10.2174/15680096112091191
Autor:
Judit Hohmann, Kendra F. Barnes, Deepak Bhatia, Anupam Bishayee, Erzsébet Háznagy-Radnai, Altaf S. Darvesh, Roslin J. Thoppil
Publikováno v:
Current Cancer Drug Targets. 12:1244-1257
Hepatocellular carcinoma (HCC), considered to be one of the most lethal cancers with almost >1 million deaths reported annually worldwide, remains a devastating disease with no known effective cure. Hence, chemopreventive strategies come into play, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3629a973facaac5b80a0bb717b7fb9a3
https://doi.org/10.2174/156800912803987968
https://doi.org/10.2174/156800912803987968