Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Rosivaldo S Borges"'
Autor:
Taysa Ribeiro Schalcher, Rosivaldo S Borges, Michael D Coleman, João Batista Júnior, Claudio G Salgado, Jose Luiz F Vieira, Pedro R T Romão, Fabio R Oliveira, Marta Chagas Monteiro
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85712 (2014)
This study aims to assess the oxidative stress in leprosy patients under multidrug therapy (MDT; dapsone, clofazimine and rifampicin), evaluating the nitric oxide (NO) concentration, catalase (CAT) and superoxide dismutase (SOD) activities, glutathio
Externí odkaz:
https://doaj.org/article/a750570a33e04e86b1c15fb3a76ff366
Autor:
Leonard D. R. Acho, Edinilze S. C. Oliveira, Simone B. Carneiro, Fernanda Paula A. Melo, Leilane de S. Mendonça, Renyer A. Costa, Rosivaldo S. Borges, Marcos B. Machado, Hector H. F. Koolen, Igor Rafael dos S. Magalhães, Emersom S. Lima
Publikováno v:
AppliedChem, Vol 4, Iss 2, Pp 140-156 (2024)
Diabetes mellitus is a chronic metabolic disease that is mainly characterized by hyperglycemia. Chalcones and their derivatives have demonstrated promising pharmacological potential for the treatment of diabetes. The aim of the study was to evaluate
Externí odkaz:
https://doaj.org/article/0af28575067340cc9b2084ff2e294fbf
Autor:
Rosivaldo S. Borges, Wanda S. Costa, Ellen P. C. Gurrão, Luiz H. C. Holanda, Alanna C. L. F. Sousa, Joyce K. L. Vale, Cláudio N. Alves, Albérico B. F. da Silva
Publikováno v:
Química Nova, Vol 45, Iss 9, Pp 1160-1166 (2022)
An experimental and theoretical approach on oxidative metabolism of paracetamol was applied for the pharmaceutical chemistry learning. Classical reactions, functional group identification, structural parameter, and chemical reactivity using frontier
Externí odkaz:
https://doaj.org/article/594a470ba7334b9e92eda1fb98ccefab
Autor:
Cleydson B. R. Santos, Cleison C. Lobato, Sirlene S. B. Ota, Rai C. Silva, Renata C. V. S. Bittencourt, Jofre J. S. Freitas, Elenilze F. B. Ferreira, Marília B. Ferreira, Renata C. Silva, Anderson B. De Lima, Joaquín M. Campos, Rosivaldo S. Borges, José A. H. M. Bittencourt
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1584 (2023)
The design, synthesis, and evaluation of novel non-steroidal anti-inflammatory drugs (NSAIDs) with better activity and lower side effects are big challenges today. In this work, two 5-acetamido-2-hydroxy benzoic acid derivatives were proposed, increa
Externí odkaz:
https://doaj.org/article/3c7c83face0f40d4a86f319b8878dae4
Autor:
Igor V.F. dos Santos, Rosivaldo S. Borges, Guilherme M. Silva, Lúcio R. de Lima, Ruan S. Bastos, Ryan S. Ramos, Luciane B. Silva, Carlos H. T. P. da Silva, Cleydson B. R. dos Santos
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Skin Cancer (SC) is among the most common type of cancers worldwide. The search for SC therapeutics using molecular modeling strategies as well as considering natural plant-derived products seems to be a promising strategy. The phytochemical Rocaglam
Externí odkaz:
https://doaj.org/article/ceba2dfb1eda4294b784bf49e6c08bb4
Autor:
Ivanete C. Palheta, Lanalice R. Ferreira, Joyce K. L. Vale, Osmarina P. P. Silva, Anderson M. Herculano, Karen R. H. M. Oliveira, Antonio M. J. Chaves Neto, Joaquín M. Campos, Cleydson B. R. Santos, Rosivaldo S. Borges
Publikováno v:
Molecules, Vol 25, Iss 14, p 3300 (2020)
Sesamol is a phenolic derivative. Its antioxidant activity is low than that of Trolox and depends on benzodioxole moiety. Thus, a molecular modification strategy through alkylation, inspired by natural and synthetic antioxidants, was studied by molec
Externí odkaz:
https://doaj.org/article/987bb0a8fed545d2aa8048c4e88482a2
Autor:
Rosely Maria dos Santos Cavaleiro, Tarciso Silva de Andrade Filho, Rosivaldo S. Borges, Tais Souza Sá Pereira, Antonio Maia de Jesus Chaves Neto, Raul Nunes de Carvalho Junior, Fabio Luiz Paranhos Costa, Tiago da Silva Arouche, Phelipe Seiichi Martins Tanoue
Publikováno v:
Journal of Nanoscience and Nanotechnology. 21:5499-5509
Hormones are a dangerous group of molecules that can cause harm to humans. This study based on classical molecular dynamics proposes the nanofiltration of wastewater contaminated by hormones from a computer simulation study, in which the water and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0248bdca76654f682c2f47e05da8bf
https://doi.org/10.1166/jnn.2021.19467
https://doi.org/10.1166/jnn.2021.19467
Autor:
Paul V. Bernhardt, Rosivaldo S. Borges, José Rogério A. Silva, Jerônimo Lameira, Thiago de Melo e Silva, Craig M. Williams, Edikarlos Brasil, Luciana Morais Canavieira, Cláudio Nahum Alves
Publikováno v:
Molecular Simulation. 47:762-770
Tyrosinase (TYR) is a key enzyme that catalyzes the synthesis of melanin in plants, microorganisms and mammalian cells. Kojic acid (KA) is a well-known TYR inhibitor widely used as a popular cosmetic skin-lightening ingredient. However, KA is reporte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fdbf0218a9182669e4845034bf8ef02
https://doi.org/10.1080/08927022.2021.1926455
https://doi.org/10.1080/08927022.2021.1926455
Autor:
Davi do Socorro Barros Brasil, Rosivaldo S. Borges, Igor V. F. dos Santos, Williams Jorge da Cruz Macêdo, Vitor H. S. Sanches, Renato Araújo da Costa, Adonay S. de Carvalho, Elenilze F. B. Ferreira, Cleison C. Lobato, Cleydson B. R. Santos, Kelton L. B. Santos, Rai C. Silva
Publikováno v:
Journal of Computational and Theoretical Nanoscience. 17:4855-4865
Hidroxyvouacapan-6α-7β, 17β-lactone (HVL) is a synthetic derivative of 6α, 7β-dihydroxyvouacapan-17β-oic acid (ADV) which was isolated from the fruits of Pterodon polygalaeflorus Benth. Both compounds showed anti-inflammatory and analgesic acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a1b62f534708d8466022a1f2970c86ae
https://doi.org/10.1166/jctn.2020.9461
https://doi.org/10.1166/jctn.2020.9461
Autor:
Marcus Vinicius Pereira dos Santos Nascimento, Eduardo Monguilhott Dalmarco, André F. Vilvert, Rosivaldo S. Borges
Publikováno v:
Current Bioactive Compounds. 16:593-605
Background:Paracetamol (p-aminophenol) and salicylates are nonsteroidal antiinflammatory drugs that are widely used in the general population. The adverse effects of both drugs continue to be a focus of the pharmaceutical industry in the development
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e24f7791288f864d3ae141068ed0c54e
https://doi.org/10.2174/1573407215666190211150700
https://doi.org/10.2174/1573407215666190211150700