Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Rosita Accardi"'
Autor:
Lucia Minoni, Maria Carmen Romero-Medina, Assunta Venuti, Cécilia Sirand, Alexis Robitaille, Gennaro Altamura, Florence Le Calvez-Kelm, Daniele Viarisio, Katia Zanier, Martin Müller, Rosita Accardi, Massimo Tommasino
Publikováno v:
mSphere, Vol 5, Iss 4 (2020)
ABSTRACT The beta human papillomaviruses (HPVs) are subdivided into 5 species (beta-1 to beta-5), and they were first identified in the skin. However, the beta-3 species appears to be more highly represented in the mucosal epithelia than in the skin.
Externí odkaz:
https://doaj.org/article/7fed5835d4c643c08345daeb18f76606
Autor:
Maria Carmen Romero-Medina, Assunta Venuti, Giusi Melita, Alexis Robitaille, Maria Grazia Ceraolo, Laura Pacini, Cecilia Sirand, Daniele Viarisio, Valerio Taverniti, Purnima Gupta, Mariafrancesca Scalise, Cesare Indiveri, Rosita Accardi, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008792 (2020)
Tumor suppressors can exert pro-proliferation functions in specific contexts. In the beta human papillomavirus type 38 (HPV38) experimental model, the viral proteins E6 and E7 promote accumulation of a wild-type (WT) p53 form in human keratinocytes (
Externí odkaz:
https://doaj.org/article/19529eda6e3248b1a5424e8ae1c92500
Autor:
Hector Hernandez-Vargas, Henri Gruffat, Marie Pierre Cros, Audrey Diederichs, Cécilia Sirand, Romina C. Vargas-Ayala, Antonin Jay, Geoffroy Durand, Florence Le Calvez-Kelm, Zdenko Herceg, Evelyne Manet, Christopher P. Wild, Massimo Tommasino, Rosita Accardi
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-17 (2017)
Abstract Epstein-Barr virus (EBV) was identified as the first human virus to be associated with a human malignancy, Burkitt’s lymphoma (BL), a pediatric cancer endemic in sub-Saharan Africa. The exact mechanism of how EBV contributes to the process
Externí odkaz:
https://doaj.org/article/cf771775f0f0480bba14d8ec7e78bb0a
Autor:
Davide Degli Esposti, Athena Sklias, Sheila C. Lima, Stéphanie Beghelli-de la Forest Divonne, Vincent Cahais, Nora Fernandez-Jimenez, Marie-Pierre Cros, Szilvia Ecsedi, Cyrille Cuenin, Liacine Bouaoun, Graham Byrnes, Rosita Accardi, Anne Sudaka, Valérie Giordanengo, Hector Hernandez-Vargas, Luis Felipe Ribeiro Pinto, Ellen Van Obberghen-Schilling, Zdenko Herceg
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Head and neck squamous cell carcinomas (HNSCCs) represent a heterogeneous group of cancers for which human papilloma virus (HPV) infection is an emerging risk factor. Previous studies showed promoter hypermethylation in HPV(+) oro
Externí odkaz:
https://doaj.org/article/0ce6fd97cea74c50a1320df391d31efc
Autor:
Daniele Viarisio, Karin Müller-Decker, Rosita Accardi, Alexis Robitaille, Matthias Dürst, Katrin Beer, Lars Jansen, Christa Flechtenmacher, Matthias Bozza, Richard Harbottle, Catherine Voegele, Maude Ardin, Jiri Zavadil, Sandra Caldeira, Lutz Gissmann, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 14, Iss 1, p e1006783 (2018)
Cutaneous beta human papillomavirus (HPV) types are suspected to be involved, together with ultraviolet (UV) radiation, in the development of non-melanoma skin cancer (NMSC). Studies in in vitro and in vivo experimental models have highlighted the tr
Externí odkaz:
https://doaj.org/article/7fa4403cea6f40ffa5dbfb8e53cb8dce
Autor:
Marie-Laure Plissonnier, Thomas Lahlali, Maud Michelet, Fanny Lebossé, Jessica Cottarel, Melanie Beer, Grégory Neveu, David Durantel, Birke Bartosch, Rosita Accardi, Sophie Clément, Andrea Paradisi, Mojgan Devouassoux-Shisheboran, Shirit Einav, Patrick Mehlen, Fabien Zoulim, Romain Parent
Publikováno v:
PLoS Biology, Vol 14, Iss 3, p e1002421 (2016)
Hepatitis C virus (HCV) is an oncogenic virus associated with the onset of hepatocellular carcinoma (HCC). The present study investigated the possible link between HCV infection and Netrin-1, a ligand for dependence receptors that sustains tumorigene
Externí odkaz:
https://doaj.org/article/d7215e0feb24458d9d605c1241958551
Autor:
Maha Siouda, Cecilia Frecha, Rosita Accardi, Jiping Yue, Cyrille Cuenin, Henri Gruffat, Evelyne Manet, Zdenko Herceg, Bakary S Sylla, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 10, Iss 5, p e1004125 (2014)
The DOK1 tumor suppressor gene encodes an adapter protein that acts as a negative regulator of several signaling pathways. We have previously reported that DOK1 expression is up-regulated upon cellular stress, via the transcription factor E2F1, and d
Externí odkaz:
https://doaj.org/article/e6e18cb857244a5ea9da090b3c3287f5
Autor:
Jenny Leitz, Miriam Reuschenbach, Claudia Lohrey, Anja Honegger, Rosita Accardi, Massimo Tommasino, Manuel Llano, Magnus von Knebel Doeberitz, Karin Hoppe-Seyler, Felix Hoppe-Seyler
Publikováno v:
PLoS Pathogens, Vol 10, Iss 3, p e1003957 (2014)
The expression of the human papillomavirus (HPV) E6/E7 oncogenes is crucial for HPV-induced malignant cell transformation. The identification of cellular targets attacked by the HPV oncogenes is critical for our understanding of the molecular mechani
Externí odkaz:
https://doaj.org/article/a8b5d9aa003a411fa6cda92b7f94430c
Autor:
Rosita Accardi, Ikbal Fathallah, Henri Gruffat, Giuseppe Mariggiò, Florence Le Calvez-Kelm, Catherine Voegele, Birke Bartosch, Hector Hernandez-Vargas, James McKay, Bakary S Sylla, Evelyne Manet, Massimo Tommasino
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003186 (2013)
Many studies have proved that oncogenic viruses develop redundant mechanisms to alter the functions of the tumor suppressor p53. Here we show that Epstein-Barr virus (EBV), via the oncoprotein LMP-1, induces the expression of ΔNp73α, a strong antag
Externí odkaz:
https://doaj.org/article/2daa063bc6114b1cb45f39acefab311a
Autor:
Maria V Chiantore, Serena Vannucchi, Rosita Accardi, Massimo Tommasino, Zulema A Percario, Gabriele Vaccari, Elisabetta Affabris, Gianna Fiorucci, Giovanna Romeo
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36909 (2012)
Interferon (IFN)-β inhibits cell proliferation and affects cell cycle in keratinocytes transformed by both mucosal high risk Human Papilloma Virus (HPV) and cutaneous HPV E6 and E7 proteins. In particular, upon longer IFN-β treatments, cutaneous HP
Externí odkaz:
https://doaj.org/article/7eeee567c95549ba8b21bc2064af161b