Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rosie G. Albarran-Zeckler"'
Publikováno v:
Neuron. 73(2):317-332
SummaryWe identified subsets of neurons in the brain that coexpress the dopamine receptor subtype-2 (DRD2) and the ghrelin receptor (GHSR1a). Combination of FRET confocal microscopy and Tr-FRET established the presence of GHSR1a:DRD2 heteromers in hy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de6bb38074b27af325d1331f84186a84
The growth hormone (GH) secretagogue receptor (GHS-R1a) is a G protein-coupled receptor (GPCR) expressed in the brain as well as other areas of the body. In the early 1990s, this receptor was expression cloned in MERCK laboratories by using a group o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::255963b6bb69c86d500cd5b5a089b993
https://doi.org/10.1159/000346042
https://doi.org/10.1159/000346042
Although the hormone ghrelin is best known for its stimulatory effect on appetite and regulation of growth hormone release, it is also reported to have beneficial effects on learning and memory formation in mice. Nevertheless, controversy exists abou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33369032c5a37aa1fda77eb8053ec0de
https://europepmc.org/articles/PMC3361606/
https://europepmc.org/articles/PMC3361606/
Publikováno v:
Peptides. 32(11)
Ghrelin is a hormone made in the stomach and known primarily for its growth hormone releasing and orexigenic properties. Nevertheless, ghrelin through its receptor, the GHS-R1a, has been shown to exert many roles including regulation of glucose homeo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85926105825d7fde6009091b6fbd625f
https://pubmed.ncbi.nlm.nih.gov/21781995
https://pubmed.ncbi.nlm.nih.gov/21781995
Autor:
Andras Kern, Alicia Faruzzi Brantley, Celine Ullrich, Maria Mavrikaki, Roy G. Smith, Rosie G. Albarran-Zeckler
Publikováno v:
Cell. (5):1176-1190
SummaryThe ghrelin receptor (GHSR1a) and dopamine receptor-1 (DRD1) are coexpressed in hippocampal neurons, yet ghrelin is undetectable in the hippocampus; therefore, we sought a function for apo-GHSR1a. Real-time single-molecule analysis on hippocam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0adce8807d3bd65362237350b8a1efbf