The role of Nkx3.2 in chondrogenesis

Autor: Roshni S. Rainbow, Heenam Kwon, Li Zeng

Publikováno v: Frontiers in Biology. 9:376-381

Transcription factor, Nkx3.2, is a member of the NK family of developmental genes and is expressed during embryogenesis in a variety of mammalian model organisms, including chicken and mouse. It was first identified in Drosophila as the Bagpipe (bap)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acdde26fd7b6f1be44a41f73e021fa75
https://doi.org/10.1007/s11515-014-1321-3

Muscle cell-derived factors inhibit inflammatory stimuli-induced damage in hMSC-derived chondrocytes

Autor: Heenam Kwon, Rucsanda C. Preda, Roshni S. Rainbow, David L. Kaplan, Andrea T. Foote, Li Zeng

Publikováno v: Osteoarthritis and Cartilage. 21:990-998

Summary Objective Pro-inflammatory cytokines play an important role in inducing cartilage degradation during osteoarthritis pathogenesis. Muscle is a tissue that lies near cartilage in situ . However, muscle's non-loading biochemical effect on cartil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bef3ea439414d4c57dc1c194ede2704
https://doi.org/10.1016/j.joca.2013.04.011

Analysis of the trajectory of osteoarthritis development in a mouse model by serial near-infrared fluorescence imaging of matrix metalloproteinase activities

Autor: Averi A. Leahy, Daisy S. Nakamura, Brian H. Tracey, Shadi Abdar Esfahani, Carrie K. Hui, Andrea T. Foote, Li Zeng, Roshni S. Rainbow, Umar Mahmood

Publikováno v: Arthritisrheumatology (Hoboken, N.J.). 67(2)

Osteoarthritis (OA) is a chronic disorder that causes long-term disability and is associated with joint injury, aging, and obesity (1). OA is characterized by joint cartilage destruction and is accompanied by chondrocyte cell death and osteophyte for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e99292b60ec90f5fd4afda0fa0436cb4
https://pubmed.ncbi.nlm.nih.gov/25385707

Contributors

Autor: Sascha Abramson, D. Michael Ackermann, Robert Akins, Richard Anders, Phillip J. Andersen, James M. Anderson, James A. Ankrum, Kristi S. Anseth, Joe Antonucci, Sarah Atzet, Stephen F. Badylak, Gail D. Baura, Ravi V. Bellamkonda, Serena M. Best, Sarindr Bhumiratana, Richard W. Bianco, Jack C. Bokros, Harvey S. Borovetz, Adele L. Boskey, Justin L. Brown, Bryan N. Brown, Stanley A. Brown, John B. Brunski, Fred Cahn, Alastair Campbell Ritchie, Arnold I. Caplan, Richard L. Carpenedo, Ashutosh Chilkoti, Sangwon Chung, Elisa Cimetta, Gary Cleary, Isaac P. Clements, André Colas, Kelly P. Coleman, Daniel E. Conway, Stuart L. Cooper, Bill Costerton, Arthur J. Coury, Crystal Cunanan, Jim Curtis, Antonio D’Amore, Patrick DeMeo, Tejal A. Desai, Sabine Dickens, Gonzalo Domingo, Elaine Duncan, Suzanne G. Eskin, David W. Feigal, Lino Ferreira, Jason Fuller, Robert P. Gallegos, Ellen Gawalt, Kaustabh Ghosh, Bilal Ghosn, Thomas W. Gilbert, Drew Elizabeth Glaser, Amandine Godier-Furnemont, Wayne R. Gombotz, David W. Grainger, Gary L. Grunkemeier, S. Adam Hacking, Nadim James Hallab, Luanne Hall-Stoodley, Stephen R. Hanson, Axel D. Haubold, Kip D. Hauch, Kenneth R. Hawkins, Daniel E. Heath, Douglas L. Helm, Larry L. Hench, Arne Hensten, Ryan T. Hill, Christopher Hobson, Simon P. Hoerstrup, Allan S. Hoffman, Thomas A. Horbett, Jeffrey A. Hubbell, Mark S. Humayun, Ray Ideker, Donald E. Ingber, Rakhi Jain, Jean Jacob, Joshua James Jacobs, Nils Jacobsen, Ruyun Jin, Richard J. Johnson, Jeffrey M. Karp, F. Kurtis Kasper, Sandeep Kathju, Ali Khademhosseini, Sungwon Kim, Martin W. King, Lothar W. Kleiner, Joachim Kohn, Heidi E. Koschwanez, Sangamesh G. Kumbar, Catherine K. Kuo, Lisa LaFleur, Matthew T. Lahti, Byron Lambert, Robert Langer, Cato T. Laurencin, David Lee-Parritz, Jack E. Lemons, Mark Levin, Robert J. Levy, Gregory M. Lewerenz, Wan-Ju Li, Chien-Chi Lin, Fang Liu, William G. Lowrie, Ying Lu, Michael J. Lysaght, Robert Maidhof, J.N. Mansbridge, M. Cristina, L. Martins, Jeffrey Martin, Jay P. Mayesh, Todd C. McDevitt, Larry V. McIntire, Katharine Merrit, Claudio Migliaresi, Antonios G. Mikos, Carl E. Misch, Richard N. Mitchell, Robert B. More, Christa W. Moss, Jennifer M. Munson, Melba Navarro, Robert M. Nerem, Rei Ogawa, Britlyn D. Orgill, Dennis P. Orgill, Robert F. Padera, Abhay Pandit, Kinam Park, Anil S. Patel, Roger B. Peck, P. Hunter Peckham, Nicholas A. Peppas, Maria Nunes Pereira, Josep Planell, Ketul C. Popat, Glenn D. Prestwich, Suzie H. Pun, John Rabolt, Roshni S. Rainbow, Taufiek Rajab, Buddy D. Ratner, William M. Reichert, Andrew L. Rivard, Adrian P. Rowley, Gang Ruan, Michael Sacks, Debanjan Sarkar, Sebastian Schaefer, Christine E. Schmidt, Frederick J. Schoen, Stacey C. Schutte, Michael V. Sefton, Shalaby W. Shalaby, Mark Shirtliff, Marc A. Simon, Milind Singh, Steven M. Slack, Francis A. Spelman, Albert Starr, Patrick S. Stayton, Roger Steinert, Paul Stoodley, Shalu Suri, Thomas Ming Swi Chang, Nina Tandon, Armand R. Tanguay, M. Scott Taylor, Grace S.L. Teo, Charles K. Thodeti, Joshua Tolkoff, Matthew Treiser, Rocky S. Tuan, Erik I. Tucker, Ramakrishna Venugopalan, Angela R. Vicari, Christopher Viney, Jessica M. Voight, Gordana Vunjak-Novakovic, William R. Wagner, Lian Wang, Karen R. Wasiluk, David Christopher Watts, Bernhard H. Weigl, James D. Weiland, John J. Whalen, David F. Williams, Rachel L. Williams, John T. Wilson, Clive G. Wilson, Jessica Winter, Michael F. Wolf, Jeremy C. Wright, Paul Yager, Weian Zhao

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f355b2eb00298d8b1e8f27d076d908c4
https://doi.org/10.1016/b978-0-08-087780-8.00150-9

Inflammation and Joint Tissue Interactions in OA: Implications for Potential Therapeutic Approaches

Autor: Roshni S. Rainbow, Weiping Ren, Li Zeng

Publikováno v: Arthritis
Arthritis, Vol 2012 (2012)

It is increasingly recognized that the pathogenesis of cartilage degradation in osteoarthritis (OA) is multifactorial and involves the interactions between cartilage and its surrounding tissues. These interactions regulate proinflammatory cytokine-me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85209b5ae4407823b0e20232c5884831
https://pubmed.ncbi.nlm.nih.gov/22745906