Zobrazeno 1 - 10
of 185
pro vyhledávání: '"Roshini S, Abraham"'
Autor:
Hongchuan Li, Md Ahasanur Rahman, Michael Ruesch, Caprice D. Eisele, Erik M. Anderson, Paul W. Wright, Jennie Cao, Shashikala Ratnayake, Qingrong Chen, Chunhua Yan, Daoud Meerzaman, Roshini S. Abraham, Aharon G. Freud, Stephen K. Anderson
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113454- (2023)
Summary: Previous studies of the murine Ly49 and human KIR gene clusters implicated competing sense and antisense promoters in the control of variegated gene expression. In the current study, an examination of transcription factor genes defines an ab
Externí odkaz:
https://doaj.org/article/53ef519c8e7344d8ac994b0e279e76e5
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/2992da11d53d48799b83e65b33159312
Autor:
Ludmila Perelygina, Raeesa Faisthalab, Emily Abernathy, Min-hsin Chen, LiJuan Hao, Lionel Bercovitch, Diana K. Bayer, Lenora M. Noroski, Michael T. Lam, Maria Pia Cicalese, Waleed Al-Herz, Arti Nanda, Joud Hajjar, Koen Vanden Driessche, Shari Schroven, Julie Leysen, Misha Rosenbach, Philipp Peters, Johannes Raedler, Michael H. Albert, Roshini S. Abraham, Hemalatha G. Rangarjan, David Buchbinder, Lisa Kobrynski, Anne Pham-Huy, Julie Dhossche, Charlotte Cunningham Rundles, Anna K. Meyer, Amy Theos, T. Prescott Atkinson, Amy Musiek, Mehdi Adeli, Ute Derichs, Christoph Walz, Renate Krüger, Horst von Bernuth, Christoph Klein, Joseph Icenogle, Fabian Hauck, Kathleen E. Sullivan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Rubella virus (RuV) has recently been found in association with granulomatous inflammation of the skin and several internal organs in patients with inborn errors of immunity (IEI). The cellular tropism and molecular mechanisms of RuV persistence and
Externí odkaz:
https://doaj.org/article/42a46da9868e480f8c8f79db28a8fb27
Publikováno v:
Viral Immunology. 36:144-148
Autor:
Christopher C. Dvorak, Elie Haddad, Jennifer Heimall, Elizabeth Dunn, Rebecca H. Buckley, Donald B. Kohn, Morton J. Cowan, Sung-Yun Pai, Linda M. Griffith, Geoffrey D.E. Cuvelier, Hesham Eissa, Ami J. Shah, Richard J. O’Reilly, Michael A. Pulsipher, Nicola A.M. Wright, Roshini S. Abraham, Lisa Forbes Satter, Luigi D. Notarangelo, Jennifer M. Puck
Publikováno v:
Journal of Allergy and Clinical Immunology. 151:539-546
Severe combined immunodeficiency (SCID) results from defects in the differentiation of hematopoietic stem cells into mature T lymphocytes, with additional lymphoid lineages affected in particular genotypes. In 2014, the Primary Immune Deficiency Trea
Publikováno v:
Thrombosis Update, Vol 1, Iss , Pp 100002- (2020)
Atypical hemolytic uremic syndrome (aHUS) is a thrombotic microangiopathy (TMA) characterized by dysregulation of the alternative pathway of complement. Heterozygous variants in complement and complement regulatory proteins may increase risk for aHUS
Externí odkaz:
https://doaj.org/article/b5d52f1f6c9740369e58c456fcffb55f
Autor:
Jennifer R. Yonkof, Ajay Gupta, Cesar M. Rueda, Shamlal Mangray, Benjamin T. Prince, Hemalatha G. Rangarajan, Mohammad Alshahrani, Elizabeth Varga, Timothy P. Cripe, Roshini S. Abraham
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
CARMIL2 deficiency is a rare combined immunodeficiency (CID) characterized by defective CD28-mediated T cell co-stimulation, altered cytoskeletal dynamics, and susceptibility to Epstein Barr Virus smooth muscle tumors (EBV-SMTs). Case reports associa
Externí odkaz:
https://doaj.org/article/87b4ac74073b41caa02885e1d944b91c
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/0eaa22161c1b4bc7813bc4b60be09a28
Autor:
David Buchbinder, Matthew J. Smith, Misako Kawahara, Morton J. Cowan, Jeffrey S. Buzby, Roshini S. Abraham
Publikováno v:
Blood Advances, Vol 2, Iss 15, Pp 1828-1832 (2018)
Abstract: DNA ligase 4 deficiency (LIG4-SCID) causes lymphopenia (T-B-NK+) and a radiosensitive SCID (RS-SCID) phenotype. We demonstrate, for the first time, flow cytometric-based kinetic analysis of phosphorylated H2AX (γH2AX) in lymphocyte subsets
Externí odkaz:
https://doaj.org/article/7156acbe38c14fd5a5c2d4a1ecebca7c
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/eaf251be9cdc49f2a8e14240e86d9322