Výsledky vyhledávání - "Roshika Ravi"

Engineering a Hyperstable Yersinia pestis Outer Membrane Protein Ail Using Thermodynamic Design

Autor: Anjana George, Roshika Ravi, Pankaj Bharat Tiwari, Shashank Ranjan Srivastava, Vikas Jain, Radhakrishnan Mahalakshmi

Publikováno v: J Am Chem Soc

Development of viable therapeutics to effectively combat tier I pneumopathogens such as Yersinia pestis requires a thorough understanding of proteins vital for pathogenicity. The host invasion protein Ail, although indispensable for Yersinia pathogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a960d6e10a6b545b0a9c870c52548b6d
https://europepmc.org/articles/PMC7612368/

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Molecular Switch between Structural Compaction and Thermodynamic Stability by the Xxx-Pro Interface in Transmembrane β-Barrels

Autor: Anjana George, Bharat Ramasubramanian Iyer, Roshika Ravi, Swadha Gupta, Henna Noordeen, Meera Daulatrao Pawar, Radhakrishnan Mahalakshmi

Publikováno v: Biochemistry. 59(3)

Transmembrane β-barrel scaffolds found in outer membrane proteins are formed and stabilized by a defined pattern of interstrand intraprotein H-bonds, in hydrophobic lipid bilayers. Introducing the conformationally constrained proline in β-barrels c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98a5e52336de1829349d94d112aaae0
https://pubmed.ncbi.nlm.nih.gov/31777252

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