The predictive capability of immunohistochemistry and DNA sequencing for determining TP53 functional mutation status: a comparative study of 41 glioblastoma patients.

Autor: Roshandel AK; College of Agriculture and Life Sciences, Virginia Tech, Blacksburg, VA 24061, USA.; The Fralin Biomedical Research Institute at VTC, Roanoke, VA 24016, USA., Busch CM; The Fralin Biomedical Research Institute at VTC, Roanoke, VA 24016, USA.; Virginia Tech School of Neuroscience, Blacksburg, VA 24061, USA.; Carilion Clinic, Division of Neurosurgery, Roanoke, VA 24014, USA.; Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA., Mullekom JV; Department of Statistics (MC0439), Hutcheson Hall, Blacksburg, VA 24061, USA., Cuoco JA; Carilion Clinic, Division of Neurosurgery, Roanoke, VA 24014, USA.; Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA., Rogers CM; Virginia Tech School of Neuroscience, Blacksburg, VA 24061, USA.; Carilion Clinic, Division of Neurosurgery, Roanoke, VA 24014, USA.; Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA., Apfel LS; Virginia Tech School of Neuroscience, Blacksburg, VA 24061, USA.; Carilion Clinic, Division of Neurosurgery, Roanoke, VA 24014, USA.; Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA., Marvin EA; Virginia Tech School of Neuroscience, Blacksburg, VA 24061, USA.; Carilion Clinic, Division of Neurosurgery, Roanoke, VA 24014, USA.; Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA., Sontheimer HW; The Fralin Biomedical Research Institute at VTC, Roanoke, VA 24016, USA.; Virginia Tech School of Neuroscience, Blacksburg, VA 24061, USA., Umans RA; The Fralin Biomedical Research Institute at VTC, Roanoke, VA 24016, USA.

Publikováno v: Oncotarget [Oncotarget] 2019 Oct 22; Vol. 10 (58), pp. 6204-6218. Date of Electronic Publication: 2019 Oct 22 (Print Publication: 2019).