Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Roshanak Ghazanfari"'
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture
Publikováno v:
STAR Protocols, Vol 2, Iss 2, Pp 100420- (2021)
Summary: In vitro differentiation of human pluripotent stem cells (hPSCs) offers a genetically tractable system to examine the physiology and pathology of human tissue development and differentiation. We have used this approach to model the earliest
Externí odkaz:
https://doaj.org/article/a918438e9d6f4dd4af6e4015bae93202
Autor:
Hongzhe Li, Roshanak Ghazanfari, Dimitra Zacharaki, Nicholas Ditzel, Joan Isern, Marja Ekblom, Simón Méndez-Ferrer, Moustapha Kassem, Stefan Scheding
Publikováno v:
Stem Cell Reports, Vol 3, Iss 6, Pp 965-974 (2014)
Human bone marrow (BM) contains a rare population of nonhematopoietic mesenchymal stromal cells (MSCs), which are of central importance for the hematopoietic microenvironment. However, the precise phenotypic definition of these cells in adult BM has
Externí odkaz:
https://doaj.org/article/72210011abe144f1a889606746a5fbe7
Autor:
Joan Isern, Beatriz Martín-Antonio, Roshanak Ghazanfari, Ana M. Martín, Juan A. López, Raquel del Toro, Abel Sánchez-Aguilera, Lorena Arranz, Daniel Martín-Pérez, María Suárez-Lledó, Pedro Marín, Melissa Van Pel, Willem E. Fibbe, Jesús Vázquez, Stefan Scheding, Álvaro Urbano-Ispizúa, Simón Méndez-Ferrer
Publikováno v:
Cell Reports, Vol 3, Iss 5, Pp 1714-1724 (2013)
Strategies for expanding hematopoietic stem cells (HSCs) include coculture with cells that recapitulate their natural microenvironment, such as bone marrow stromal stem/progenitor cells (BMSCs). Plastic-adherent BMSCs may be insufficient to preserve
Externí odkaz:
https://doaj.org/article/ad21aadd3f874fca80991a37cbdb96eb
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 6, Iss 1, Pp 1-5 (2012)
Introduction: Stromal cells having preadipocyte characteristics can be isolated from adipose tissue, propagated in vitro and induced to differentiate in vitro toward the osteogenic, adipogenic, myogenic and chondrogenic lineages when treated with est
Externí odkaz:
https://doaj.org/article/df4b65c0d2cb45ef9b5d76c190a654f6
Publikováno v:
International Journal of Hematology-Oncology and Stem Cell Research, Vol 6, Iss 1 (2012)
Introduction: Stromal cells having preadipocyte characteristics can be isolated from adipose tissue, propagated in vitro and induced to differentiate in vitro toward the osteogenic, adipogenic, myogenic and chondrogenic lineages when treated with est
Externí odkaz:
https://doaj.org/article/a697dc892df84885ba14bc0276de78cf
In vitro differentiation of human pluripotent stem cells into the B lineage using OP9-MS5 co-culture
Publikováno v:
STAR Protocols
STAR Protocols, Vol 2, Iss 2, Pp 100420-(2021)
STAR Protocols, Vol 2, Iss 2, Pp 100420-(2021)
Summary In vitro differentiation of human pluripotent stem cells (hPSCs) offers a genetically tractable system to examine the physiology and pathology of human tissue development and differentiation. We have used this approach to model the earliest s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::067796299d2b74490cd3facc15d99153
https://www.repository.cam.ac.uk/handle/1810/318376
https://www.repository.cam.ac.uk/handle/1810/318376
Publikováno v:
European Journal of Haematology. 101:57-67
Objective: Philadelphia-negative myeloproliferative neoplasms (MPNs) commonly share hyperactive JAK-STAT signaling affecting hematopoietic stem cells (HSC) and their progeny. The JAK1/2 inhibitor Ruxolitinib has remarkable clinical efficacy, includin
Publikováno v:
Stem Cells and Development
Human bone marrow contains a population of non-hematopoietic stromal stem/progenitor cells (BMSCs), which play a central role for bone marrow stroma and the hematopoietic microenvironment. However, the precise characteristics and potential stem cell
Autor:
Dimitra Zacharaki, Roshanak Ghazanfari, Shamit Soneji, Stefan Scheding, Hooi Ching Lim, Hongzhe Li
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-10 (2017)
Scientific Reports
Scientific Reports
Bone marrow mesenchymal stromal cells (BM-MSCs) are a rare population of cells that gives rise to skeletal tissues and the hematopoietic stroma in vivo. Recently, we have demonstrated that BM-MSCs fulfill stringent in vivo stem cell criteria when pro
Publikováno v:
Annals of the New York Academy of Sciences. 1370(1)
Bone marrow (BM) contains a rare population of mesenchymal stromal cells (MSCs), which have been characterized as nonhematopoietic skeletal progenitor cells with central importance for the hematopoietic microenvironment. Classically, MSCs are isolate