Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Rosewell Shaw A"'
Autor:
Bora Lim, Caroline Porter, Mae Woods, Masataka Suzuki, Daisuke Morita, Amanda Rosewell Shaw, Greyson Biegert, Spyridoula Vasileiou
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 12 (2024)
Background Oncolytic adenoviruses (OAds) are the most clinically tested viral vectors for solid tumors. However, most clinically tested “Armed” OAds show limited antitumor effects in patients with various solid tumors even with increased dosages
Externí odkaz:
https://doaj.org/article/2a3df0b8c8644bb4adc656bda3d66c80
Autor:
Ada Irmak Özcan, Arianexys Aquino Lόpez, Alexandra N. Wolff, Audrey Ma, Amanda Rosewell Shaw, Masataka Suzuki, Malcolm K. Brenner, Mary K. McKenna
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 3, Pp 101279- (2024)
Systemic delivery of oncolytic and immunomodulatory adenoviruses may be required for optimal effects on human malignancies. Mesenchymal stromal cells (MSCs) can serve as delivery systems for cancer therapeutics due to their ability to transport and s
Externí odkaz:
https://doaj.org/article/bca70b3e6e2c445b940f2f3be75993c5
Autor:
Rosewell Shaw, Amanda, Morita, Daisuke, Porter, Caroline E., Tu, Eric, Biegert, Greyson W., Agrawal, Sonia, Durham, Nicholas, Brenner, Malcolm K., Suzuki, Masataka
Publikováno v:
In Molecular Therapy: Oncology 19 December 2024 32(4)
Publikováno v:
Molecular Therapy: Oncolytics, Vol 23, Iss , Pp 571-581 (2021)
Adenoviruses are well characterized and thus easily modified to generate oncolytic vectors that directly lyse tumor cells and can be “armed” with transgenes to promote lysis, antigen presentation, and immunostimulation. Oncolytic adenoviruses (OA
Externí odkaz:
https://doaj.org/article/ab2e398736ad433cb85891d8c8c779f2
Publikováno v:
In Molecular Therapy - Oncolytics 17 December 2021 23:571-581
Publikováno v:
In Molecular Therapy 3 February 2021 29(2):505-520
Autor:
Amanda Rosewell Shaw, Caroline E. Porter, Tiffany Yip, Way-Champ Mah, Mary K. McKenna, Matthew Dysthe, Youngrock Jung, Robin Parihar, Malcolm K. Brenner, Masataka Suzuki
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-13 (2021)
Rosewell Shaw et al. show that a previously developed immunotherapy strategy, coupling oncolytic adenoviral immunotherapy with clinically tested HER2-specific CAR T-cells, is effective against pancreatic ductal adenocarcinoma (PDAC). This combination
Externí odkaz:
https://doaj.org/article/6c619b9e136441a696783c518011c56f
Autor:
Porter, Caroline E., Rosewell Shaw, Amanda, Jung, Youngrock, Yip, Tiffany, Castro, Patricia D., Sandulache, Vlad C., Sikora, Andrew, Gottschalk, Stephen, Ittman, Michael M., Brenner, Malcolm K., Suzuki, Masataka
Publikováno v:
In Molecular Therapy 6 May 2020 28(5):1251-1262
Autor:
Amanda Rosewell Shaw, Masataka Suzuki
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 15, Iss , Pp 418-429 (2019)
Adenoviruses are a commonly utilized virus for gene therapy platforms worldwide. Since adenovirus components are characterized as highly immunogenic, their immunogenicity inhibits the widespread use of adenoviral vectors to treat genetic disorders. H
Externí odkaz:
https://doaj.org/article/50df80ba26214a9c986894ff6d85c771
Autor:
Natalie Chen, Daniel Wang, Caroline E. Porter, Amanda Rosewell Shaw, Catherine R. Robertson, Mae L. Woods, Ya Xu, Greyson Biegert, Alphi Kuriakose, Tao Wang, Bambi J. Grilley, Helen Heslop, Malcolm K. Brenner, Masataka Suzuki, Bora Lim
Publikováno v:
Cancer Research. 83:P3-06
Background: Metastatic breast cancer (MBC) which causes significant morbidity and mortality worldwide is in need of more effective treatment regimens. In combination with chemotherapy, anti-PD1 antibody pembrolizumab has been shown to prolong progres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6a9e7988bd5db1108bcea19315c3350
https://doi.org/10.1158/1538-7445.sabcs22-p3-06-04
https://doi.org/10.1158/1538-7445.sabcs22-p3-06-04