Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Roser M. Pujol"'
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Daniel Mouzo, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
Publikováno v:
Haematologica, Vol 108, Iss 10 (2023)
Clinical trials have shown that lentiviral-mediated gene therapy can ameliorate bone marrow failure (BMF) in nonconditioned Fanconi anemia (FA) patients resulting from the proliferative advantage of corrected FA hematopoietic stem and progenitor cell
Externí odkaz:
https://doaj.org/article/d53a95898f024aef96171022924acc08
Autor:
Julián Sevilla, Susana Navarro, Paula Rio, Rebeca Sánchez-Domínguez, Josune Zubicaray, Eva Gálvez, Eva Merino, Elena Sebastián, Carmen Azqueta, José A. Casado, José C. Segovia, Omaira Alberquilla, Massimo Bogliolo, Francisco J. Román-Rodríguez, Yari Giménez, Lise Larcher, Rocío Salgado, Roser M. Pujol, Raquel Hladun, Ana Castillo, Jean Soulier, Sergi Querol, Jesús Fernández, Jonathan Schwartz, Nagore García de Andoín, Ricardo López, Albert Catalá, Jordi Surralles, Cristina Díaz-de-Heredia, Juan A. Bueren
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 22, Iss , Pp 66-75 (2021)
Difficulties in the collection of hematopoietic stem and progenitor cells (HSPCs) from Fanconi anemia (FA) patients have limited the gene therapy in this disease. We have investigated (ClinicalTrials.gov, NCT02931071) the safety and efficacy of filgr
Externí odkaz:
https://doaj.org/article/ff619351134c4b8d89b9a48f91e2e8e9
Autor:
Miren Lasaga, Paula Río, Amaia Vilas-Zornoza, Nuria Planell, Susana Navarro, Diego Alignani, Beatriz Fernández-Varas, Josune Zubicaray, Roser M. Pujol, Eileen Nicoletti, Jonathan D. Schwartz, Julián Sevilla, Marina Ainciburi, Asier Ullate-Agote, Jordi Surrallés, Rosario Perona, Leandro Sastre, Felipe Prosper, David Gomez-Cabrero, Juan A. Bueren
SUMMARY PARAGRAPH Fanconi anemia (FA) is a monogenic inherited disease associated with mutations in genes that encode for proteins participating in the FA/BRCA DNA repair pathway. Mutations in FA genes result in chromosomal instability and cell death
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db0bf3349847b11087227da6bf0f549
https://doi.org/10.1101/2021.07.20.21260460
https://doi.org/10.1101/2021.07.20.21260460