Zobrazeno 1 - 10 of 72 pro vyhledávání: '"Roser IGLESIAS"'
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Akademický článek
The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes
Autor: Tania Quesada-López, Rubén Cereijo, Jean-Valery Turatsinze, Anna Planavila, Montserrat Cairó, Aleix Gavaldà-Navarro, Marion Peyrou, Ricardo Moure, Roser Iglesias, Marta Giralt, Decio L. Eizirik, Francesc Villarroya
Publikováno v: Nature Communications, Vol 7, Iss 1, Pp 1-17 (2016)
GPR120 is a G-protein-coupled receptor that binds polyunsaturated fatty acids. Here, the authors show that GPR120 is upregulated in brown fat in cold-exposed mice, and mediates thermogenic activation of brown fat via a mechanism that, at least in par
Externí odkaz: https://doaj.org/article/d43c898e4b2a465d95d9fbdc8cf28cde
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3
GPR120 controls neonatal brown adipose tissue thermogenic induction
Autor: Francesc Villarroya, Laura Campderrós, Roser Iglesias, Tania Quesada-López, Marta Giralt, Aleix Gavaldà-Navarro, Samantha Morón-Ros
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Adaptive induction of thermogenesis in brown adipose tissue (BAT) is essential for the survival of mammals after birth. We show here that G protein-coupled receptor protein 120 (GPR120) expression is dramatically induced after birth in mouse BAT. GPR
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf3486428f02d673595268568d937a3
https://pubmed.ncbi.nlm.nih.gov/31361546
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CXCL14, a Brown Adipokine that Mediates Brown-Fat-to-Macrophage Communication in Thermogenic Adaptation
Autor: Roser Iglesias, Teresa Mampel, Rubén Cereijo, Decio L. Eizirik, Jean Valéry Turatsinze, Francesc Villarroya, Marion Peyrou, Aleix Gavaldà-Navarro, Montserrat Cairó, Tania Quesada-López, David Sánchez-Infantes, Samantha Morón-Ros, Joan Villarroya, Marta Giralt
Publikováno v: Cell Metabolism, 28 (5
Cell Metabolism
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname
CELL METABOLISM
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
The beneficial effects of brown adipose tissue (BAT) are attributed to its capacity to oxidize metabolites and produce heat, but recent data suggest that secretory properties of BAT may also be involved. Here, we identify the chemokine CXCL14 (C-X-C
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467670891bcb45a1b006b70b59635f7d
http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/283840
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5
Sirt1 mediates the effects of a short-term high-fat diet on the heart
Autor: Ibon Redondo-Angulo, Marta Giralt, Roser Iglesias, Anna Planavila, Joan Villarroya, Francesc Villarroya
Publikováno v: The Journal of Nutritional Biochemistry. 26:1328-1337
High-fat diet leads to development of cardiac dysfunction through molecular mechanisms poorly known. The aim of this study is to elucidate the early events in cardiac dysfunction caused by a high-fat diet, before massive alterations due to obesity an
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7647432d8d3b240fcce37fb6fd898e
https://doi.org/10.1016/j.jnutbio.2015.07.029
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Pref-1 in brown adipose tissue: specific involvement in brown adipocyte differentiation and regulatory role of C/EBPδ
Autor: Maria Carmen Carmona, Roser Iglesias, Francesc Villarroya, Hei Sook Sul, Josep A. Villena, Marta Giralt, Jordi Armengol, Elayne Hondares
Publikováno v: Biochemical Journal. 443:799-810
Pref-1 (pre-adipocyte factor-1) is known to play a central role in regulating white adipocyte differentiation, but the role of Pref-1 in BAT (brown adipose tissue) has not been analysed. In the present study we found that Pref-1 expression is high in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd0afe6fec418403fd1e9d154f3a955a
https://doi.org/10.1042/bj20111714
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Peroxisome Proliferator-activated Receptor α (PPARα) Induces PPARγ Coactivator 1α (PGC-1α) Gene Expression and Contributes to Thermogenic Activation of Brown Fat
Autor: María Monsalve, Elayne Hondares, Meritxell Rosell, Yolanda Olmos, Roser Iglesias, Marta Giralt, Francesc Villarroya, Julieta Díaz-Delfín
Publikováno v: Journal of Biological Chemistry. 286:43112-43122
Peroxisome proliferator activated receptor α (PPARα) is a distinctive marker of the brown fat phenotype that has been proposed to coordinate the transcriptional activation of genes for lipid oxidation and for thermogenic uncoupling protein 1 in bro
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::acbd3bfeb293f996d659818c1a36f1c3
https://doi.org/10.1074/jbc.m111.252775
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Peroxisome Proliferator-activated Receptor-γ Coactivator-1α Controls Transcription of the Sirt3 Gene, an Essential Component of the Thermogenic Brown Adipocyte Phenotype
Autor: Marta Giralt, Roser Iglesias, Josep A. Villena, Francesc Villarroya, Elayne Hondares, Albert Giralt, Francesc Ribas, Julieta Díaz-Delfín
Publikováno v: Journal of Biological Chemistry. 286:16958-16966
Sirt3 (silent mating type information regulation 2, homolog 3), a member of the sirtuin family of protein deacetylases with multiple actions on metabolism and gene expression is expressed in association with brown adipocyte differentiation. Using Sir
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be26fc4b1954309d030dca196aae061b
https://doi.org/10.1074/jbc.m110.202390
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9
Sirt1 acts in association with PPAR to protect the heart from hypertrophy, metabolic dysregulation, and inflammation
Autor: Roser Iglesias, A Planavila, Marta Giralt, Francesc Villarroya
Publikováno v: Cardiovascular Research. 90:276-284
Aims A complex set of metabolic and inflammatory processes are involved in the development of cardiac hypertrophy. Accumulating evidence indicates an important role for Sirt1 in cardiac function, whereas peroxisome proliferator-activated receptor-α
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83151fdf83045ba9c11a31b2ae2eb50b
https://doi.org/10.1093/cvr/cvq376
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10
Hepatic FGF21 Expression Is Induced at Birth via PPARα in Response to Milk Intake and Contributes to Thermogenic Activation of Neonatal Brown Fat
Autor: Marta Giralt, Roser Iglesias, Elayne Hondares, Meritxell Rosell, Francesc Villarroya, Frank J. Gonzalez
Publikováno v: Cell Metabolism. 11(3):206-212
Plasma FGF21 levels and hepatic FGF21 gene expression increase dramatically after birth in mice. This induction is initiated by suckling, requires lipid intake, is impaired in PPARalpha null neonates, and is mimicked by treatment with the PPARalpha a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8d2428c5a444009dc75f78548e33b7b
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