Výsledky vyhledávání - "Rosenkaimer, F"

Isolated limb perfusion with tumour necrosis factor-α and melphalan with or without interferon-γ; for the treatment of in-transit melanoma metastases

Autor: Rosenkaimer F, G. Steinmann, Ferdy J. Lejeune, J Clarke, Bin B. R. Kroon, S Hiemstra, Danielle Lienard, G Towse, Heimen Schraffordt Koops, A. M. M. Eggermont, P Schmitz

Publikováno v: Melanoma Research. 9:491-502

This open, multicentre, randomized phase II trial was conducted to determine the effect of isolated limb perfusion (ILP) with tumour necrosis factor-alpha (TNFalpha) in combination with melphalan with or without interferon-gamma (IFNgamma) in patient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b2fa3fef6caf040b60d3dff6ac4283
https://doi.org/10.1097/00008390-199910000-00009

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Isolated limb perfusion with tumour necrosis factor-alpha and melphalan with or without interferon-gamma for the treatment of in-transit melanoma metastases: a multicentre randomized Phase II study

Autor: Lienard, D, Eggermont, AMM, Kroon, B, Towse, G, Schmitz, P, Steinmann, G, Rosenkaimer, F, Lejeune, FJ, Schraffordt Koops, H.

Publikováno v: Melanoma Research, 9(5), 491-502. LIPPINCOTT WILLIAMS & WILKINS

This open, multicentre, randomized phase II trial was conducted to determine the effect of isolated limb perfusion (ILP) with tumour necrosis factor-alpha (TNF alpha) in combination with melphalan with or without interferon-gamma (IFN gamma) in patie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ceea5560b743087fbb9dca0cd5cad139
https://research.rug.nl/en/publications/80339b91-f56c-4eb9-b9d0-52767a05b529

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RATIONALE FOR USING TNF-ALPHA AND CHEMOTHERAPY IN REGIONAL THERAPY OF MELANOMA

Autor: LEJEUNE, F, LIENARD, D, EGGERMONT, A, KOOPS, HS, ROSENKAIMER, F, GERAIN, J, KLAASE, J, KROON, B, VANDERVEKEN, J, SCHMITZ, P

Publikováno v: Journal of Cellular Biochemistry, 56(1), 52-61. Wiley-Blackwell

Recombinant tumor necrosis factor-alpha (rTNF alpha) has potent antitumor activity in experimental studies on human tumor xenografts. However, in humans, the administration of rTNF alpha is hampered by severe systemic side-effects. The maximum tolera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::5234b5dde91736b3d23b7a5357c419e7
https://research.rug.nl/en/publications/f1d2630f-d203-454c-9526-4c8510751efd

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CLINICAL-EXPERIENCE WITH HIGH-DOSE TUMOR-NECROSIS-FACTOR-ALPHA IN REGIONAL THERAPY OF ADVANCED MELANOMA

Autor: LEJEUNE, F, LIENARD, D, EGGERMONT, A, KOOPS, HS, KROON, B, GERAIN, J, ROSENKAIMER, F, SCHMITZ, P

Publikováno v: Circulatory shock, 43(4), 191-197

Isolated perfusion of the limbs (ILP) allows the delivery of high dose rTNF alpha in a closed system with acceptable side-effects. A protocol with a triple-drug regimen was based on the reported synergism of rTNF alpha with chemotherapy, with interfe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::ec61d234335cf77f54b2b6bf72ef213f
https://research.rug.nl/en/publications/f0a29ce5-b0ce-480e-9d13-93b7e309b738

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Akademický článek

Rationale for using TNFα and chemotherapy in regional therapy of melanoma.

Autor: Lejeune, F., Liénard, D., Eggermont, A., Koops, H. Schraffordt, Rosenkaimer, F., Gérain, J., Klaase, J., Kroon, B., Vanderveken, J., Schmitz, P.

Publikováno v: Journal of Cellular Biochemistry; Sep1994, Vol. 56 Issue 1, p52-61, 10p

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